Cloning, expression analysis, and chromosomal localization of HIP1R, an isolog of huntingtin interacting protein (HIP1)

Journal of Human Genetics

Volumn 43, Issue 4, 1998, Pages 268-271

  Seki, Naohiko ^a   Muramatsu, Masa Aki ^b,c   Sugano, Sumio ^d   Suzuki, Yutaka ^d   Nakagawara, Akira ^e   Ohhira, Miki ^e   Hayashi, Akiko ^a   Hori, Tada Aki ^a   Saito, Toshiyuki ^a  

^a NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

^b Helix Research Institute   (Japan)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

^e CHIBA CANCER CENTER   (Japan)

Author keywords

Chromosome 12q24; Full length enriched cDNA library; Huntingtin interacting protein (HIP1); Leucine zipper; Neuroblastoma

Indexed keywords

HUNTINGTIN; MESSENGER RNA; PROTEIN;

ARTICLE; CHROMOSOMAL LOCALIZATION; CHROMOSOME 12Q; FLUORESCENCE IN SITU HYBRIDIZATION; GENE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; HUNTINGTON CHOREA; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

AMINO ACID SEQUENCE; CARRIER PROTEINS; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 12; CLONING, MOLECULAR; DNA-BINDING PROTEINS; FUNGAL PROTEINS; GENE EXPRESSION; HUMANS; HUNTINGTON DISEASE; IN SITU HYBRIDIZATION, FLUORESCENCE; MOLECULAR SEQUENCE DATA; NEUROBLASTOMA; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE ALIGNMENT; TUMOR CELLS, CULTURED; VESICULAR TRANSPORT PROTEINS;

EID: 0031700674     PISSN: 14345161     EISSN: None     Source Type: Journal    
DOI: 10.1007/s100380050087     Document Type: Article

References (22)

1. Andrew SE, Goldberg YP, Kremer B, Telenius H, Theilmann J, Adam S, Starr E, Squitieri F, Lin B, Kalchman MA, Graham RK, Hayden MR (1993) The relationship between trinucleotide (CAG) repeat length and clinical feature of Huntington's disease. Nat Genet 4: 398-403
2. Burke JR, Enghild JJ, Martin ME, Jou YS, Myers RM, Roses AD, Vance JM, Strittmatter WJ (1996) Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH. Nat Med 2: 347-350
3. Duyao M, Ambrose C, Myers R, Novelletto A, Persichetti F, Frontali M, Folstein S, Ross C, Franz M, Abbott M, Gray J, Conneally P, Young A, Penney J, Hollingsworth Z, Shoulson I, Lazzarini A, Falek A, Koroshetz W, Sax D, Bird E, Vonsattel J, Bonilla E, Alvir J, Conde JB, Cha JH, Dure L, Gomez F, Ramos M, Sanchez-Ramos J, Snodgrass S, de Young M, Wexler N, Moscowitz C, Penchaszadeh G, MacFarlane H, Anderson M, Jenkins B, Srinidhi J, Barnes G, Gusella J, MacDonald M (1993) Trinucleotide repeat length instability and age of onset in Huntington disease. Nat Genet 4: 387-392
4. Harper PS (1991) Huntington's disease. WB Saunders, London
5. Isozumi K, DeLong R, Kaplan J, Deng HX, Iqbal Z, Hung WY, Wilhelmsen KC, Hentati A, Pericak-Vance MA, Siddique T (1996) Linkage of scapuloperoneal spinal muscular atrophy to chromosome 12q24.1-q24.31. Hum Mol Genet 5: 1377-1382
6. John M, Briand JP, Granger-Schnarr M, Schnarr M (1994) Two pairs of oppositely charged amino acids from Jun and Fos confer heterodimerization to GCN4 leucine zipper. J Biol Chem 269: 16247-16253
7. Kalchman MA, Graham RK, Xia G, Koide HB, Hodgson JG, Graham KC, Goldberg YP, Gietz RD, Pickart CM, Hayden MR (1996) Huntingtin is ubiquitinated and interacts with a specific ubiquitin-conjugating enzyme. J Biol Chem 271: 19385-19394
8. Kalchman MA, Koide HB, McCutcheon K, Graham RK, Nichol K, Nishiyama K, Kazemi-Esfarjani P, Lynn FC, Wellington C, Metzler M, Goldberg YP, Kanazawa I, Gietz RD, Hayden MR (1997) HIP1, a human homologue of S. cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain. Nat Genet 16: 44-53
9. Kremer B, Goldberg P, Andrew SE, Theilmann J, Telenius H, Zeisler J, Squitieri F, Lin B, Bassett A, Almqvist E, Bird TD, Hayden MR (1994) A worldwide study of the Huntington's disease mutation: the sensitivity and specificity of measuring CAG repeats. N Engl J Med 330: 1401-1406
10. Li XJ, Li SH, Sharp AH, Nucifora FC Jr, Schilling G, Lanahan A, Worley P, Snyder SH, Ross CA (1995) A huntingtin-associated protein enriched in brain with implications for pathology. Nature 378: 398-402
11. Maruyama K, Sugano S (1994) Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. Gene 138: 171-174
12. Ohhira M, Seki N, Nagase T, Suzuki E, Nomura N, Ohara O, Hatton M, Sakaki Y, Eki T, Murakami Y, Saito T, Ichikawa H, Ohki M (1997) Gene identification in 1.6-Mb region of the Down syndrome region on chromosome 21. Genome Res 7: 47-58
13. Pearlman JA, Powaser PA, Elledge SJ, Caskey CT (1994) Troponin T is capable of binding dystrophin via a leucine zipper. FEBS Lette 354: 183-186
14. Ross CA (1995) When more is less: pathogenesis of glutamine repeat neurodegenerative disease. Neuron 15: 493-496
15. Saito T, Seki N, Ishii H, Ohhira M, Hayashi A, Kozuma S, Hori T (1997) Complementary DNA cloning and chromosomal mapping of a novel phosphatidylinositol kinase gene. DNA Res 4: 301-305
16. Seki N, Nimura Y, Ohhira M, Saito T, Ichimiya S, Nomura N, Nakagawara A (1997) Identification and chromosome assignment of a human gene encoding a novel phosphatidylinositol-3 kinase. DNA Res 4: 355-358
17. Snell RG, MacMillan JC, Cheadle JP, Fenton I, Lazarou LP, Davies P, MacDonald ME, Gusella JF, Harper PS, Shaw DJ (1993) Relationship between trinucleotide repeat expansion and phenotypic variation in Huntington's disease. Nat Genet 4: 393-397
18. Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (1997) Construction and characterization of a full length-enriched and 5′-end-enriched cDNA library. Gene 200: 149-156
19. The Huntington's Disease Collaborative Research Group (1993) A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 72: 971-983
20. Timmerman V, De Jonghe P, Simokovic S, Lofgren A, Beuten J, Nelis E, Ceuterick C, Martin JJ, Van Broeckhoven C (1996) Distal hereditary motor neuropathy type II (distal HMN II): mapping of a locus to chromosome 12q24. Hum Mol Genet 5: 1065-1069
21. Wanker EE, Rovira C, Scherzinger E, Hasenbank R, Walter S, Tait D, Colicelli J, Lehrach H (1997) HIP-I: a huntingtin interacting protein isolated by the yeast two-hybrid system. Hum Mol Genet 6: 487-495
22. Zoghbi HY (1996) The expanding world of ataxins. Nat Genet 14: 237-238