Establishing cell polarity in development

Nature Cell Biology

Volumn 4, Issue 2, 2002, Pages

  Wodarz, Andreas ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CELL PROTEIN; MICROTUBULE PROTEIN;

ANIMAL CELL; CAENORHABDITIS ELEGANS; CELL MATURATION; CELL POLARITY; CELL TYPE; CONTROLLED STUDY; CYTOSKELETON; DROSOPHILA; EPITHELIUM CELL; FEMALE; GENETIC CODE; MAMMAL CELL; MICROTUBULE; NONHUMAN; OOCYTE; OOCYTE DEVELOPMENT; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; REVIEW; VERTEBRATE; ZYGOTE;

ANIMALS; CAENORHABDITIS ELEGANS; CELL POLARITY; CYTOSKELETAL PROTEINS; DROSOPHILA MELANOGASTER; EPITHELIAL CELLS; HUMANS; MODELS, BIOLOGICAL; OOGENESIS; ZYGOTE;

ANIMALIA; CAENORHABDITIS; CAENORHABDITIS ELEGANS; MAMMALIA; VERTEBRATA;

EID: 0036172159     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/ncb0202-e39     Document Type: Review

References (72)

1. PARsing embryonic polarity
2. Cell division: Asymmetric cell division during animal development
3. Asymmetric cell division: Fly neuroblast meets worm zygote
4. Asymmetric division of Drosophila neural stem cells: A basis for neural diversity
5. Cytoplasmic flow and the establishment of polarity in C. elegans 1-cell embryos
6. Early patterning of the C. elegans embryo
7. Cell polarity in the early Caenorhabditis elegans embryo
8. Specification of the anteroposterior axis in Caenorhabditis elegans
9. Anucleate Caenorhabditis elegans sperm can crawl, fertilize oocytes and direct anterior-posterior polarization of the 1-cell embryo
10. Polarization of the anterior-posterior axis of C. elegans is a microtubule-directed process
11. The spd-2 gene is required for polarization of the anteroposterior axis and formation of the sperm asters in the Caenorhabditis elegans zygote
12. When cells tell their neighbors which direction to divide
13. Identification of genes required for cytoplasmic localization in early C. elegans embryos
14. Polarity controls forces governing asymmetric spindle positioning in the Caenorhabditis elegans embryo
15. Atypical protein kinase C cooperates with PAR-3 to establish embryonic polarity in Caenorhabditis elegans
16. CDC-42 controls early cell polarity and spindle orientation in C. elegans
17. CDC-42 regulates PAR protein localization and function to control cellular and embryonic polarity in C. elegans
18. A non-muscle myosin required for embryonic polarity in Caenorhabditis elegans
19. The nonmuscle myosin regulatory light chain gene mlc-4 is required for cytokinesis, anterior-posterior polarity, and body morphology during Caenorhabditis elegans embryogenesis
20. The coronin-like protein POD-1 is required for anterior-posterior axis formation and cellular architecture in the nematode Caenorhabditis elegans
21. OOC-3, a novel putative transmembrane protein required for establishment of cortical domains and spindle orientation in the P(1) blastomere of C. elegans embryos
22. Pod-2, along with pod-1, defines a new class of genes required for polarity in the early Caenorhabditis elegans embryo
23. Mutations in ooc-5 and ooc-3 disrupt oocyte formation and the reestablishment of asymmetric PAR protein localization in two-cell Caenorhabditis elegans embryos
24. Multiple effects of colchicine on oogenesis in Drosophila: Induced sterility and switch of potential oocyte to nurse-cell developmental pathway
25. Microtubules are a general component of mRNA localization systems in Drosophila oocytes
26. Morphogenesis of the Drosophila fusome and its implications for oocyte specification
27. Alpha-spectrin is required for germline cell division and differentiation in the Drosophila ovary
28. The Drosophila fusome, a germline-specific organelle, contains membrane skeletal proteins and functions in cyst formation
29. Hu-li tai shao, a gene required for ring canal formation during Drosophila oogenesis, encodes a homolog of adducin
30. Germline cyst formation in Drosophila
31. The microtubule motor cytoplasmic dynein is required for spindle orientation during germline cell divisions and oocyte differentiation in Drosophila
32. Lis1, the Drosophila homolog of a human lissencephaly disease gene, is required for germline cell division and oocyte differentiation
33. Drosophila Lissencephaly-1 functions with Bic-D and dynein in oocyte determination and nuclear positioning
34. A central role for microtubules in the differentiation of Drosophila oocytes
35. The fusome organizes the microtubule network during oocyte differentiation in Drosophila
36. Reciprocal localization of Nod and kinesin fusion proteins indicates microtubule polarity in the Drosophila oocyte, epithelium, neuron and muscle
37. Intercellular migration of centrioles in the germarium of Drosophila melanogaster. An electron microscopic study
38. Centrosome migration into the Drosophila oocyte is independent of BicD and egl. and of the organisation of the microtubule cytoskeleton
39. The Drosophila homolog of C. elegans PAR-1 organizes the oocyte cytoskeleton and directs oskar mRNA localization to the posterior pole
40. A Drosophila melanogaster homologue of Caenorhabditis elegans par-1 acts at an early step in embryonic-axis formation
41. Drosophila par-1 is required for oocyte differentiation and microtubule organization
42. PAR-1 is required for the maintenance of oocyte fate in Drosophila
43. MARK, a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption
44. Control of spindle orientation in Drosophila by the Par-3-related PDZ- domain protein Bazooka
45. Bazooka and PAR-6 are required with PAR-1 for the maintenance of oocyte fate in Drosophila
46. Origins of cell polarity
47. New perspectives on mechanisms involved in generating epithelial cell polarity
48. Cadherins in embryonic and neural morphogenesis
49. Integrin signaling
50. Catenins and zonula occludens-1 form a complex during early stages in the assembly of tight junctions
51. Differentiation of the epithelial apical junctional complex during mouse preimplantation development: A role for rab13 in the early maturation of the tight junction
52. Assembly of tight junctions during early vertebrate development
53. Role of tight junctions in establishing and maintaining cell polarity
54. Tight junction, a platform for trafficking and signaling protein complexes
55. The tight junction: Morphology to molecules
56. Multifunctional strands in tight junctions
57. An atypical PKC directly associates and colocalizes at the epithelial tight junction with ASIP, a mammalian homologue of Caenorhabditis elegans polarity protein PAR-3
58. A human homolog of the C. elegans polarity determinant par-6 links rac and cdc42 to PKCzeta signaling and cell transformation
59. A mammalian Par-3-Par-6 complex implicated in CdC42/Rac1 and a PKC signalling and cell polarity
60. The cell polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42
61. The mammalian homologue of the Caenorhabditis elegans polarity protein PAR-6 is a binding partner for the Rho GTPases Cdc42 and Rac1
62. Human homologues of the Caenorhabditis elegans cell polarity protein PAR6 as an adaptor that links the small GTPases Rac and Cdc42 to atypical protein kinase C
63. Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia- specific junctional structures
64. PAR-6 regulates aPKC activity in a novel way and mediates cell-cell contact-induced formation of the epithelial junctional complex
65. The cell polarity protein ASIP/PAR-3 directly associates with junctional adhesion molecule (JAM)
66. Junctional adhesion molecule (JAM) binds to PAR-3: A possible mechanism for the recruitment of PAR-3 to tight junctions
67. Junctional adhesion molecule interacts with the PDZ domain-containing proteins AF-6 and ZO-1
68. Homophilic interaction of junctional adhesion molecule
69. E-cadherin-mediated cell-cell attachment activates Cdc42
70. Integrin-Mediated Activation of Cdc42 Controls Cell Polarity in Migrating Astrocytes through PKCzeta
71. Mammalian homologues of C. elegans PAR-1 are asymmetrically localized in epithelial cells and may influence their polarity