Therapeutic administration of nitric oxide synthase inhibitors reverses hyperalgesia but not inflammation in a rat model of polyarthritis

Pain

Volumn 95, Issue 3, 2002, Pages 215-223

  Tedesco, Laura S ^a   Fuseler, John ^b   Grisham, Matthew ^a   Wolf, Robert ^b   Roerig, Sandra C ^a  

^a LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^b LA   (United States)

Author keywords

Allodynia; Arthritis; Hyperalgesia; Indomethacin; Nitric oxide

Indexed keywords

ANTIINFLAMMATORY AGENT; DRINKING WATER; INDOMETACIN; N (6) (1 IMINOETHYL)LYSINE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; PEPTIDOGLYCAN POLYSACCHARIDE; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHRONIC DISEASE; CONTROLLED STUDY; DISEASE MODEL; DOSE TIME EFFECT RELATION; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; HYPERALGESIA; INFLAMMATION; MALE; MECHANICAL STIMULATION; NERVE TRACT; NOCICEPTIVE STIMULATION; NONHUMAN; PAIN THRESHOLD; POLYARTHRITIS; PRIORITY JOURNAL; RAT; RESPONSE TIME; THERMAL STIMULATION;

ANIMALS; ARTHRITIS; BODY WEIGHT; CYCLOOXYGENASE INHIBITORS; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; FEMALE; HEAT; HYPERALGESIA; INDOMETHACIN; LYSINE; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; PHYSICAL STIMULATION; RATS; RATS, INBRED LEW;

EID: 0036165354     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3959(01)00402-X     Document Type: Article

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