Effect of peroxynitrite on plasma extravasation, microvascular blood flow and nociception in the rat

British Journal of Pharmacology

Volumn 122, Issue 6, 1997, Pages 1083-1088

  Ridger, V C ^a   Greenacre, S A B ^a   Handy, R L C ^a   Halliwell, B ^a   Moore, P K ^a   Whiteman, M ^a   Brain, S D ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Algesia; Microvascular; Oedema formation; Peroxynitrite; Plasma extravasation

Indexed keywords

DEXAMETHASONE; INDOMETACIN; MEPYRAMINE; METHYSERGIDE; NOLPITANTIUM; PEROXYNITRITE;

ANIMAL EXPERIMENT; ARTICLE; CAPILLARY FLOW; EXTRAVASATION; HYPERALGESIA; INTRADERMAL DRUG ADMINISTRATION; LASER DOPPLER FLOWMETRY; MALE; NOCICEPTION; NONHUMAN; PLASMA; PRIORITY JOURNAL; RAT;

ANIMALS; CAPILLARY PERMEABILITY; CATALASE; EDEMA; MALE; NITRATES; PAIN; RATS; RATS, WISTAR; REGIONAL BLOOD FLOW; SKIN; SUPEROXIDE DISMUTASE;

EID: 0030817826     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701498     Document Type: Article

References (32)

1. BECKMAN, J.S., CHEN, J., ISCHIROPOULOS, H. & CROW, J.P. (1994). Oxidative chemistry of peroxynitrite. Methods Enzymol., 233, 229-240.
2. BECKMAN, J.S. & CROW, J.P. (1993). Pathological implications of nitric oxide, superoxide and peroxynitrite formation. Biochem. Soc. Trans., 21, 330-334.
3. BOOTA, A., ZAR, H., KIM, Y.M., JOHNSON, B., PITT, B. & DAVIES, P. (1996). IL-1beta stimulates superoxide and delayed peroxynitrite production by pulmonary vascular smooth muscle cells. Am. J. Physiol., 271, L932-L938.
4. BOUGHTON-SMITH, N.K., EVANS, S.M., LASZLO, F., WHITTLE, B.J.R. & MONCADA, S. (1993). The induction of nitric oxide synthase and intestinal vascular permeability by endotoxin in the rat. Br. J. Pharmacol., 110, 1189-1195.
5. BRAIN, S.D. & WILLIAMS, T.J. (1985). Inflammatory oedema induced by synergism between calcitonin gene-related peptide (CGRP) and mediators of increased vascular permeability. Br. J. Pharmacol., 86, 855-860.
6. BUSSE, R. & MULSCH, A. (1990). Induction of nitric oxide synthase by cytokines in vascular smooth muscle cells. FEBS Lett., 275, 87-90.
7. CHABOT, F., MITCHELL, J.A., QUINLAN, G.J. & EVANS, T.W. (1997). Characterization of the vasodilator properties of peroxynitrite on rat pulmonary artery: Role of poly(adenosine 5′-diphosphoribose synthase. Br. J. Pharmacol., 121, 485-490.
8. CONNOR, J.R., MANNING, P.T., SETTLE, S.L., MOORE, W.M., JEROME, G.M., WEBBER, R.K., TJOENG, F.S. & CURRIE, M.G. (1995). Suppression of adjuvant-induced arthritis by selective inhibition of inducible nitric oxide synthase. Eur. J. Pharmacol., 273, 15-24.
9. DARLEY-USMAR, V. & HALLIWELL, B. (1996). Blood radicals, reactive nitrogen species, reactive oxygen species, transition metal ions, and the vascular system. Pharm. Res., 13, 649-662.
10. DELICONSTANTINOS, G., VILLIOTOU, V. & STAVRIDES, J.C. (1996a). Increase of particulate nitric oxide synthase activity and peroxynitrite synthesis in UVB-irradiated keratinocyte membranes. Biochem. J., 320, 997-1003.
11. DELICONSTANTINOS, G., VILLIOTOU, V. & STAVRIDES, J.C. (1996b). Nitric oxide and peroxynitrite released by ultraviolet B-irradiated human endoethelial cells are possibly involved in skin erythem and inflammation. Exp. Physiol., 81, 1021-1033.
12. 2+ signaling in vascular endothelial cells. Am. J. Physiol., 270, L954-L961.
13. GREENACRE, S., RIDGER, V., WILSONCROFT, P. & BRAIN, S.D. Peroxynitrite: a mediator of increased microvascular permeability? Clin. Exptl. Pharmacol. (in press).
14. HANDY, R.L.C. & MOORE, P.K. (1996). The nitric oxide synthase inhibitor, 7-nitroindazole, inhibits carrageenan-induced hindpaw oedema in the rat. Br. J. Pharmacol., 119, 157P.
15. HANDY, R.L.C., WALLACE, P. & MOORE, P.K. (1997). 7-Nitroindazole inhibits carrageenan-induced mechanical hyperalgesia in the rat. Pharmacologist, 39, 488 (abstract).
16. JOHNSON, A. & FERRO, T.J. (1996). Nitrovasodilator repletion increases TNF-alpha-induced pulmonary edema. J. Appl. Physiol., 80, 2151-2155.
17. KAUR, H. & HALLIWELL, B. (1994). Evidence for nitric oxide-mediated oxidative damage in chronic inflammation. Nitrotyrosine in serum and synovial fluid from rheumatoid patients. FEBS Lett., 350, 9-12.
18. KONDO, S., SEGAWA, T., TANAKA, K., IZAWA, K., HASHIDA, M. & KANEMATSU, T. (1996). Mannosylated superoxide dismutase inhibits hepatic reperfusion injury in rats. J. Surg. Res., 60, 36-40.
19. LAIRD, J.M., MASON, G.S., WEBB, J., HILL, R.G. & HARGREAVES, R.J. (1996). Effects of a partial agonist and a full antagonist acting at the glycine site of the NM DA receptor on inflammation-induced mechanical hyperalgesis in rats. Br. J. Pharmacol., 117, 1487-1492.
20. LAMARQUE, D. & WHITTLE, B.J. (1995). Involvement of superoxide and xanthine oxidase in neutrophil-independent rat gastric damage induced by NO donors. Br. J. Pharmacol., 116, 1843-1848.
21. MILLER, R.A. & BRITIGAN, B.E. (1995). The formation and biologic significance of phagocyte-derived oxidants. J. Invest. Med., 43, 39-49.
22. MILLER, M.J.S., THOMPSON, J.H., ZHANG, X.J., SADOWSKAKROWICKA, H., KAKKIS, J.L., MUNSHI, U.K., SANDOVAL, M., ROSSI, J.L., ELOBY-CHILDRESS, S., BECKMAN, J.S., YE, Y.Z., RODI, J.E., MANNING, P.T., CURRIE, M.G. & CLARK, D.A. (1995). Role of inducible nitric oxide synthase expression and peroxynitrite formation in guinea pig ileitis. Gastroenterology, 109, 1475-1483.
23. MONCADA, S., PALMER, R.M.J. & HIGGS, E.A. (1991). Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol. Rev., 43, 109-141.
24. MOORE, T.M., KHIMENKO, P.L., WILSON, P.S. & TAYLOR, A.E. (1996). Role of nitric oxide in lung ischemia and reperfusion injury. Am. J. Physiol., 271, H1970-H1977.
25. NASEEM, K.M., CHIRICO, S., MOHAMMADI, B. & BRUCKDORFER, K.R. (1996). The synergism of hydrogen peroxide with plasma S-nitrosothiols in the inhibition of platelet activation. Biochem. J., 318, 759-766.
26. NUSSLER, A.K. & BILLIAR, T.R. (1993). Inflammation, immunoregulation, and inducible nitric oxide synthase. J. Leuk. Biol., 54, 171-178.
27. RACHMILEWITZ, D., STAMLER, J.S., KARMELI, F., MULLINS, M.E., SINGEL, D.J., LOSCALZO, J., XAVIER, R.J. & PODOLSKY, D.K. (1993). Peroxynitrite-induced rat colitise a new model of colonic inflammation. Gastroenterology, 105, 1681-1688.
28. RIDGER, V.C. & BRAIN, S.D. (1996). Peroxynitrite induces plasma extravasation in rat dorsal skin. Br. J. Pharmacol., 119, 56P.
29. SALVEMINI, D., WANG, Z., BOURDON, D.M., STERN, M., CURRIE, M.G. & MANNING, P.T. (1996). Evidence for peroxynitrite involvement in carrageenan-induced rat paw edema. Eur. J. Pharmacol., 303, 217-220.
30. SIRSJO, A., KARLSSON, M., GIDLOF, A., ROLLMAN, O. & TORMA, H. (1996). Increased expression of inducible nitric oxide synthase in psoriatic skin and cytokine- stimulated cultured keratinocytes. Br. J. Dermatol., 134, 643-648.
31. SPENCER, J.P.E., WONG, J., JENNER, A., ARUOMA, O.I., CROSS, C.E. & HALLIWELL, B. (1996). Base modification and strand brakage in isolated calf thymus DNA and in DNA from human skin epidermal keratinocytes exposed to peroxynitrite or 3-morpholinosydnonimine. Chem. Res. Toxicol., 9, 1152-1158.
32. YARWOOD, H., NOURSHARGH, S., BRAIN, S. & WILLIAMS, T.J. (1993). Effect of dexamethasone on neutrophil accumulation and oedema formation in rabbit skin: an investigation of site of action. Br. J. Pharmacol., 108, 959-966.