Responsiveness of rat substantia gelatinosa neurones to mechanical but not thermal stimuli revealed by in vivo patch-clamp recording

Journal of Physiology

Volumn 521, Issue 2, 1999, Pages 529-535

  Furue, H ^a   Narikawa, K ^a   Kumamoto, E ^a   Yoshimura, M ^a  

^a SAGA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; BIOCYTIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; MALE; MECHANICAL STIMULATION; NERVE STIMULATION; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; SPINAL CORD DORSAL HORN; SUBSTANTIA GELATINOSA; SYNAPSE; THERMAL STIMULATION; EVOKED RESPONSE; GLIA CELL; HINDLIMB; IN VIVO STUDY; MEMBRANE POTENTIAL; NERVE CELL; PATCH CLAMP TECHNIQUE; RECEPTIVE FIELD; STIMULUS RESPONSE;

EID: 0033406152     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-7793.1999.00529.x     Document Type: Article

References (35)

1. ALLEN, B. J., ROGERS, S. D., GHILARDI, J. R., MENNING, P. M., KUSKOWSKI, M. A., BASBAUM, A. I., SIMONE, D. A. & MANTYH, P. W. (1997). Noxious cutaneous thermal stimuli induce a graded release of endogenous substance P in the spinal cord: imaging peptide action in vivo. Journal of Neuroscience 17, 5921-5927.
2. BABA, H., YOSHIMURA, M., NISHI, S. & SHIMOJI, K. (1994). Synaptic responses of substantia gelatinosa neurones to dorsal column stimulation in rat spinal cord in vitro. Journal of Physiology 478, 87-99.
3. BEAL, J. A. & BICKNELL, H. R. JR (1985). Development and maturation of neurons in the substantia gelatinosa (SG) of the rat spinal cord. In Development, Organization, and Processing in Somatosensory Pathways, ed. ROWE, M. & WILLIS, W. D. JR, pp. 23-30. Wiley-Liss, New York.
4. BENNETT, G. J., ABDELMOUMENE, M., HAYASHI, H. & DUBNER, R. (1980). Physiology and morphology of substantia gelatinosa neurons intracellularly stained with horseradish peroxidase. Journal of Comparative Neurology 194, 809-827.
5. BROWN, A. G. (1982). The dorsal horn of the spinal cord. Quarterly Journal of Experimental Physiology 67, 193-212.
6. CERVERO, F. & IGGO, A. (1980). The substantia gelatinosa of the spinal cord. A critical review. Brain 103, 717-772.
7. DE KONINCK, Y. & HENRY, J. L. (1991). Substance P-mediated slow excitatory postsynaptic potential elicited in dorsal horn neurons in vivo by noxious stimulation. Proceedings of the National Academy of Sciences of the USA 88, 11344-11348.
8. DE KONINCK, Y, RIBEIRO-DA-SILVA, A., HENRY, J. L. & CUELLO, A. C. (1992). Spinal neurons exhibiting a specific nociceptive response receive abundant substance P-containing synaptic contacts. Proceedings of the National Academy of Sciences of the USA 89, 5073-5077.
9. 3H]glutamate-binding sites in rat central nervous system. Journal of Neuroscience 4, 2133-2144.
10. HÖKFELT, T., KELLERTH, J.-O., NILSSON, G. & PERNOW, B. (1975a). Experimental immunohistochemical studies on the localization and distribution of substance P in cat primary sensory neurons. Brain Research 100, 235-252.
11. HÖKFELT, T., KELLERTH, J.-O., NILSSON, G. & PERNOW, B. (1975b). Substance P: localization in the central nervous system and in some primary sensory neurons. Science 190, 889-890.
12. HÖKFELT, T., LJUNGDAHL, A., TERENIUS, L., ELDE, R. & NILSSON, G. (1977). Immunohistochemical analysis of peptide pathways possibly related to pain and analgesia: enkephalin and substance P. Proceedings of the National Academy of Sciences of the USA 74, 3081-3085.
13. JEFTINIJA, S. & URBAN, L. (1994). Repetitive stimulation induced potentiation of excitatory transmission in the rat dorsal horn: an in vitro study. Journal of Neurophysiology 71, 216-228.
14. KOHNO, T., KUMAMOTO, E., HIGASHI, H., SHIMOJI, K. & YOSHIMURA, M. (1999). Actions of opioids on excitatory and inhibitory transmission in substantia gelatinosa of adult rat spinal cord. Journal of Physiology 518, 803-813.
15. LIGHT, A. R. & KAVOOKJIAN, A. M. (1988). Morphology and ultrastructure of physiologically identified substantia gelatinosa (lamina II) neurons with axons that terminate in deeper dorsal horn laminae (III-V). Journal of Comparative Neurology 267, 172-189.
16. LIGHT, A. R. & PERL, E. R. (1979). Reexamination of the dorsal root projection to the spinal dorsal horn including observations on the differential termination of coarse and fine fibers. Journal of Comparative Neurology 186, 117-131.
17. LIGHT, A. R. & WILLCOCKSON, H. H. (1996). In vivo, whole-cell recordings from spinal substantia gelatinosa (Lamina II) neurons of adult rats. Society for Neuroscience Abstracts 22, 861.
18. MENÉTREY, D., CHAOUCH, A. & BESSON, J.-M. (1979). Responses of spinal cord dorsal horn neurones to non-noxious and noxious cutaneous temperature changes in the spinal rat. Pain 6, 265-282.
19. NAKATSUKA, T., PARK, J.-.S., KUMAMOTO, E., TAMAKI, T. & YOSHIMURA, M. (1999). Plastic changes in sensory inputs to rat substantia gelatinosa neurons following peripheral inflammation. Pain 82, 39-47.
20. PEI, X., VOLGUSHEV, M., VIDYASAGAR, T. R. & CREUTZFELDT, O. D. (1991). Whole cell recording and conductance measurements in cat visual cortex in vivo. NeuroReport 2, 485-488.
21. RANDIC, M., JIANG, M. C. & CERNE, R. (1993). Long-term potentiation and long-term depression of primary afferent neurotransmission in the rat spinal cord. Journal of Neuroscience 13, 5228-5241.
22. REXED, B. (1952). The cytoarchitectonic organization of the spinal cord in the cat. Journal of Comparative Neurology 96, 415-495.
23. SAKMANN, B. & NEHER, E. (1983). Single Channel Recording, pp. 3-51. Plenum Press, New York.
24. SCHNEIDER, S. P. & PERL, E. R. (1988). Comparison of primary afferent and glutamate excitation of neurons in the mammalian spinal dorsal horn. Journal of Neuroscience 8, 2062-2073.
25. SCHNEIDER, S. P. & PERL, E. R. (1994). Synaptic mediation from cutaneous mechanical nociceptors. Journal of Neurophysiology 72, 612-621.
26. SUGIURA, Y., LEE, C. L. & PERL, E. R. (1986). Central projections of identified, unmyelinated (C) afferent fibers innervating mammalian skin. Science 234, 358-361.
27. WILLIS, W. D. JR & COGGESHALL, E. E. (1991). Sensory Mechanisms of the Spinal Cord, 2nd edn, pp. 79-107. Plenum Press, New York.
28. WOOLF, C. J. & FITZGERALD, M. (1983). The properties of neurones recorded in the superficial dorsal horn of the rat spinal cord. Journal of Comparative Neurology 221, 313-328.
29. YAJIRI, Y., YOSHIMURA, M., OKAMOTO, M., TAKAHASHI, H. & HIGASHI, H. (1997). A novel slow excitatory postsynaptic current in substantia gelatinosa neurons of the rat spinal cord in vitro. Neuroscience 76, 673-688.
30. YANG, K., KUMAMOTO, E., FURUE, H., LI, Y.-Q. & YOSHIMURA, M. (1999). Action of capsaicin on dorsal root-evoked synaptic transmission to substantia gelatinosa neurons in adult rat spinal cord slices. Brain Research 830, 268-273.
31. YOSHIMURA, M. (1996). Slow synaptic transmission in the spinal dorsal horn. Progress in Brain Research 113, 443-462.
32. YOSHIMURA, M. & JESSELL, T. M. (1989). Primary afferent-evoked synaptic responses and slow potential generation in rat substantia gelatinosa neurons in vitro. Journal of Neurophysiology 62, 96-108.
33. YOSHIMURA, M. & JESSELL, T. M. (1990). Amino acid-mediated EPSPs at primary afferent synapses with substantia gelatinosa neurones in the rat spinal cord. Journal of Physiology 430, 315-335.
34. YOSHIMURA, M. & NISHI, S. (1993). Blind patch-clamp recordings from substantia gelatinosa neurons in adult rat spinal cord slices: pharmacological properties of synaptic currents. Neuroscience 53, 519-526.
35. YOSHIMURA, M., SHIMIZU, T., YAJIRI, Y., INOKUCHI, H. & NISHI, S. (1993). Primary afferent-evoked slow EPSPs and responses to substance P of dorsal horn neurons in the adult rat spinal cord slices. Regulatory Peptides 46, 407-409.