Maternal transmission of diabetes

Diabetic Medicine

Volumn 19, Issue 2, 2002, Pages 89-98

  Alcolado, J C ^a   Laji, K ^a   Gill Randall, R ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Deafness; Genetics; Maternal inheritance; Mitochondrial DNA

Indexed keywords

CARNITINE; INSULIN; MITOCHONDRIAL DNA; TRANSFER RNA; UBIDECARENONE;

B LYMPHOCYTE; CLINICAL FEATURE; CLINICAL TRIAL; DIABETIC RETINOPATHY; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE MODEL; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA POLYMORPHISM; EXTRACHROMOSOMAL INHERITANCE; GENE MUTATION; GENETIC DISORDER; GENETIC PREDISPOSITION; HUMAN; INSULIN RELEASE; LYMPHOCYTE FUNCTION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NUCLEOTIDE SEQUENCE; PANCREAS ISLET; PERCEPTION DEAFNESS; PLACENTAL TRANSFER; POINT MUTATION; REVIEW; RODENT; TREATMENT OUTCOME; UTERUS;

DIABETES MELLITUS, TYPE 2; DNA, MITOCHONDRIAL; FEMALE; GENOMIC IMPRINTING; GLUCOSE; HOMEOSTASIS; HUMANS;

EID: 0036119350     PISSN: 07423071     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1464-5491.2002.00675.x     Document Type: Review

References (98)

1. Maternally inherited diabetes mellitus: The role of mitochondrial DNA defects
2. Importance of maternal history of non-insulin dependent diabetic patients
3. On possible genetic and epigenetic modes of diabetes transmission
4. Further evidence for predominantly maternal transmission of maturity-onset type diabetes
5. Missense glucokinase mutation in maturity-onset diabetes of the young and mutation screening in late onset diabetes
6. Mutations in the hepatocyte nuclear factor 4α gene in maturity-onset diabetes of the young (MODY1)
7. Mutations in the hepatocyte nuclear factor 1α gene in maturity-onset diabetes of the young (MODY3)
8. Differences in the prevalence of diabetes and impaired glucose tolerance according to maternal or paternal history of diabetes
9. Maternal effect and familial aggregation in NIDDM
10. Maternal role in type 2 diabetes mellitus: Indirect evidence for mitochondrial inheritance
11. Excess maternal history of diabetes in Caucasian and Afro-origin non-insulin dependent diabetic patients suggests dominant maternal factors in disease transmission
12. Frequency of diabetes in family members of probands with non-insulin dependent diabetes mellitus
13. Familial aggregation of type 2 (non-insulin dependent) diabetes mellitus in South India; absence of excess maternal transmission
14. Evaluation of the importance of maternal history of diabetes and mitochondrial variation in the development of NIDDM
15. Parental history of diabetes in a population-based study
16. Parental history of diabetes in an insulin-treated diabetes registry
17. Excess maternal transmission of type 2 diabetes
18. Parent-offspring trios: A resource to facilitate the identification of Type 2 diabetes genes
19. Parental transmission of Type 2 diabetes; the Framingham offspring study
20. Influence of a familial history of diabetes on the clinical characteristics of patients with type 2 diabetes mellitus
21. Diabetes in Hong Kong Chinese; evidence for familial clustering and parental effects
22. Type 2 diabetes and maternal family history
23. Patients report maternal transmission of NIDDM but not IDDM
24. Distribution of type II diabetes in nuclear families
25. Mitochondrial DNA and human evolution
26. Asian affinities and continental radiation of the four founding native American mtDNAs
27. Phylogenetic analysis of mitochondrial DNA in Type 2 diabetes: Maternal history and ancient population expansion
28. Mitochondrial signals in glucose-stimulated insulin secretion in the beta cell
29. Beta-cell mitochondria in the regulation of insulin secretion: A new culprit in Type II diabetes
30. Mitochondrial glutamate acts as a messenger on glucose-induced insulin exocytosis
31. Normal insulin receptors in mitochondrial myopathies with ophthalmoplegia
32. Endocrine dysfunction in Kearns-Sayre syndrome
33. Maternally transmitted diabetes and deafness associated with a 10.4 Kb mitochondrial DNA deletion
34. Mitochondrial diabetes revisited
35. Mutation in mitochondrial tRNALeu (UUR) gene in a large pedigree with maternally transmitted type II diabetes mellitus and deafness
36. Diabetes mellitus associated with a pathogenic point mutation in mitochondrial DNA
37. Mitochondrial gene defects in patients with NIDDM
38. A mutation in the tRNAleu (UUR) gene associated with the MELAS subgroup of mitochondrial encephalomyopathies
39. High frequency of mutations in MODY and mitochondrial genes in Scandinavian patients with familial early-onset diabetes
40. Screening for mtDNA diabetes mutations in Pima Indians with NIDDM
41. leu (UUR) mutation at position 3243 bp in UK Caucasian Type 2 diabetic patients
42. The mitochondrial DNA A3243G mutation in Portugal: Clinical and molecular studies in 5 families
43. Mitochondrial DNA A3243G mutation in patients with early-or late-onset type 2 diabetes in Hong Kong Chinese
44. Mitochondrial gene mutations in familial non-insulin-dependent diabetes mellitus in Taiwan
45. A subtype of diabetes mellitus associated with a mutation of mitochondrial DNA
46. leu at position 3243 and spontaneous abortions in Japanese women attending a clinic for diabetic pregnancies
47. Identification of mtDNA mutation in a pedigree with gestational diabetes, Wolff-Parkinson-White syndrome and placenta accreta
48. Maternally inherited diabetes and deafness: Prevalence in a hospital diabetic population
49. Importance of searching for mtDNA defects in patients with diabetes and hearing deficit
50. The high prevalence of diabetic patients with a mutation in the mitochondrial gene in Japan
51. Molecular scanning of candidate mitochondrial tRNA genes in type 2 (non-insulin dependent) diabetes mellitus
52. Mitochondrial DNA variations in patients with Type 2 (non-insulin dependent) diabetes mellitus and a Welsh control population
53. Mitochondrial DNA variations in patients with maternally inherited diabetes and deafness syndrome
54. A patient with Type 2 diabetes mellitus associated with mutations in calcium sensing receptor gene and mitochondrial DNA
55. A new mitochondrial DNA mutation at 14577 T/C is probably a major pathogenic mutation for maternally inherited Type 2 diabetes
56. A new mitochondrial DNA mutation associated with non-insulin-dependent diabetes mellitus
57. Segregation pattern of a novel mutation in the mitochondrial tRNA glutamic acid gene associated with myopathy and diabetes mellitus
58. Identification of a large-scale mitochondrial deoxyribonucleic acid deletion in endocrinopathies and deafness: Report of two unrelated cases with diabetes and adrenal insufficiency respectively
59. Congenital encephalomyopathy and adult onset myopathy and diabetes mellitus: Different phenotypic associations of a new heteroplasmic mtDNA tRNA glutamic acid mutation
60. lleu (UUR) mutation
61. Phenotypic expression of diabetes secondary to a T14709C mutation of mitochondrial DNA
62. New mitochondrial DNA homoplasmic mutations associated with Japanese patients with Type 2 diabetes
63. Mitochondrial diabetes; investigation and identification of a novel mutation
64. A common mitochondrial DNA variant is associated with insulin resistance in adult life
65. Analysis of a polycytosine tract and heteroplasmic length variation in the mitochondrial DNA D-loop of patients with diabetes, MELAS syndrome and race-matched controls
66. Insulin resistance associated with maternally inherited diabetes and deafness
67. leu (UUR) mutation
68. Insulin resistance and impaired glucose tolerance
69. Clinical presentation of diabetes associated with a mitochondrial point mutation
70. leu (UUR) mutation in Japanese patients
71. Mitochondrial gene mutation in islet cell antibody patients who were initially NIDDM
72. Does mitochondrial genome mutation in subjects with maternally inherited diabetes and deafness decrease severity of diabetic retinopathy?
73. The retinal manifestations of mitochondrial myopathy
74. leu (UUR) mutation in mitochondrial DNA derived from patients with maternally inherited diabetes and deafness (MIDD) and progressive kidney disease
75. Molecular and histological evaluation of pancreata from patients with a mitochondrial gene mutation associated with impaired insulin secretion
76. Mitochondrial DNA, diabetes and pancreatic pathology in Kearns-Sayre syndrome
77. leu (UUR) mutation
78. Ubidecarenone in the treatment of mitochondrial myopathies: A multi-center double-blind trial
79. 10 treatment in mitochondrial encephalomyopathy
80. Could coenzyme Q10 and L-carnitine be a treatment for diabetes secondary to 3243 mutation of mtDNA?
81. 10 treatment on maternally inherited diabetes mellitus and deafness, and mitochondrial DNA 3243 (A to G) mutation
82. leu (UUR) gene
83. Spontaneous diabetes produced by selective breeding of normal Wistar rats
84. High maternal than paternal inheritance of diabetes in GK rats
85. Genetic analysis of non-insulin dependent diabetes mellitus in the GK rat
86. Mitochondrial deoxyribonucleic acid content is specifically decreased in adult, but not fetal, pancreatic islets of the Goto-Kakizaki rat, a genetic model of non-insulin-dependent diabetes
87. The BHE rat: An animal model for the study of NIDDM
88. A point mutation in the mitochondrial DNA of diabetes-prone BHE/cdb rats
89. Impaired insulin secretion and beta-cell loss in tissue-specific knockout mice with mitochondrial diabetes
90. Analysis of parent-offspring trios provides evidence for linkage and association between the insulin gene and Type 2 diabetes mediated exclusively through paternally transmitted class III variable number tandem repeat alleles
91. Klinefelter's syndrome accompanied by diabetes mellitus and diabetes insipidus
92. Diabetes mellitus in patients with aneuploid chromosome aberrations and in their parents
93. Epigenetic inheritance at the agouti locus in the mouse
94. The natural history of impaired glucose tolerance in the Pima Indians
95. Intrauterine programming of adult disease
96. Mutations in the glucokinase gene of the fetus result in reduced birth weight
97. The insulin gene VNTR type 2 diabetes, and birth weight
98. A rodent model of intra-uterine and genetic influences in Type 2 diabetes