Mitochondrial DNA A3243G mutation in patients with early- or late-onset type 2 diabetes mellitus in Hong Kong Chinese

Clinical Endocrinology

Volumn 52, Issue 5, 2000, Pages 557-564

  Ng, Maggie C Y ^a   Yeung, V T F ^a   Chow, C C ^a   Li, J K Y ^a   Smith, P R ^b   Mijovic, C H ^b   Critchley, J A J H ^a   Barnett, A H ^b   Cockram, C S ^a   Chan, J C N ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MITOCHONDRIAL DNA;

ADULT; ARTICLE; DISEASE CLASSIFICATION; FEMALE; GENE MUTATION; GENETIC ANALYSIS; HONG KONG; HUMAN; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; ONSET AGE; PATHOGENESIS; PEDIGREE ANALYSIS; PRIORITY JOURNAL;

ADULT; AGE OF ONSET; AGED; ASIAN CONTINENTAL ANCESTRY GROUP; C-PEPTIDE; CASE-CONTROL STUDIES; CHI-SQUARE DISTRIBUTION; DIABETES MELLITUS, TYPE 2; DNA, MITOCHONDRIAL; FEMALE; HONG KONG; HUMANS; MALE; MIDDLE AGED; PEDIGREE; POINT MUTATION; POLYMERASE CHAIN REACTION;

EID: 0034087941     PISSN: 03000664     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2265.2000.00989.x     Document Type: Article

References (41)

1. Alcolado, J.C. & Alcolado, R. (1991) Importance of maternal history of non-insulin-dependent diabetic patients. British Medical Journal, 302, 1178-1180.
2. Alcolado, J.C., Majid, A., Brockington, M., Sweeney, M.G., Morgan, R., Rees, A., Harding, A.E. & Barnett, A.H. (1994) Mitochondrial gene defects in patients with NIDDM. Diabetologia, 37, 372-376.
3. Anderson, S., Bankier, A.T., Barrell, B.G., de Bruijn, M.H.L., Coulson, A.R., Drouin, J., Eperon, I.C., Nierlich, D.P., Roe, B.A., Sanger, F., Schreier, P.H., Smith, A.J.H., Staden, R. & Young, I.G. (1981) Sequence and organization of the human mitochondrial genome. Nature, 290, 457-465.
4. Baldeweg, S.E. & Yudkin, J.S. (1999) Implications of the United Kingdom Prospective Diabetes Study. Primary Care, 26, 809-827.
5. Chan, J.C.N. & Cockram, C.S. (1997) Diabetes mellitus in Chinese and its implications on health care. Diabetes Care, 20, 1785-1790.
6. Chan, J.C.N., Lau, M., Wong, R., Chow, C.C., Yeung, V., Loo, K.M., Mong, M., Yeung, T., Ko, G.T.C., Li, K.Y., So, W.Y., Chan, W.B., Lu, K. & Cockram, C.S. (1997) Delivery of diabetes care - the experience at the Prince of Wales Hospital. Hospital Authority Quality Bulletin, 2, 3-21.
7. Chomyn, A., Martinuzzi, A., Yoneda, M., Daga, A., Hurko, O., Johns, D., Lai, S.T., Nonaka, I., Angelini, C. & Attardi, G. (1992) MELAS mutation in mtDNA binding site for transcription termination factor causes defects in protein synthesis and in respiration but no change in levels of upstream and downstream mature transcripts. Proceedings of the National Academy of Sciences of the United States of America, 89, 4221-4225.
8. Cockram, C.S. & Chan, J.C.N. (1999) The epidemiology of diabetes in the Western Pacific Region (excluding Japan). In: Diabetes in the New Millennium (ed. Turtle, J.R.), pp. 11-22. Pot Still Press, Sydney.
9. Cockram, C.S., Woo, J., Lau, E., Chan, J.C.N., Chan, A.Y.W. & Lau, J. (1993) The prevalence of diabetes mellitus and impaired glucose tolerance among Hong Kong Chinese adults of working age. Diabetes Research and Clinical Practice, 21, 67-73.
10. Hinokio, Y., Suzuki, S., Komatu, K., Ohtomo, M., Onoda, M., Matsumoto, M., Hirai, S., Sato, Y., Akai, H., Abe, K., Miyabayasi, S., Abe, R. & Toyota, T. (1995) A new mitochondrial DNA deletion associated with diabetic amyotrophy, diabetic myoatrophy and diabetic fatty liver. Muscle and Nerve, Supplement 3, S142-S149.
11. Janus, E.D. (1997) Cardiovascular risk factor prevalence study. Epidemiology of cardiovascular risk factors in Hong Kong. Clinical and Experimental Pharmacology and Physiology, 24, 987-988.
12. Kadowaki, T., Kadowaki, H., Mori, Y., Tobe, K., Sakuta, R., Suzuki, Y., Tanabe, Y., Sakura, H., Awata, T., Goto, Y.I., Hayakawa, T., Matsuoka, K., Kawamori, R., Kamada, T., Horai, S., Nonaka, I., Hagura, R., Akanuma, Y. & Yazaki, Y. (1994) A subtype of diabetes mellitus associated with a mutation of mitochondrial DNA. New England Journal of Medicine, 330, 962-968.
13. Kobayashi, T., Nakanishi, K., Nakase, H., Kajio, H., Okubo, M., Murase, T. & Kosaka, K. (1997) In situ characterization of islets in diabetes with a mitochondrial DNA mutation at nucleotide position 3243. Diabetes, 46, 1567-1571.
14. Larsson, N.G. & Clayton, D.A. (1995) Molecular genetic aspects of human mitochondrial disorders. Annual Review of Genetics, 29, 151-178.
15. Maassen, J.A. & Kadowaki, T. (1996) Maternally inherited diabetes and deafness: a new diabetes subtype. Diabetologia, 39, 375-382.
16. Matthews, R.D., Hosker, J.P., Rudenski, A.S., Naylor, B.A., Treacher, D.F. & Turner, R.C. (1985) Homeostatis model assessment: insulin resistance and β cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia, 28, 412-419.
17. Moses, R., Rodda, M. & Griffiths, R. (1997) Predominance of a maternal history of diabetes for patients with non-insulin-dependent diabetes mellitus. Implications for the intrauterine transmission of diabetes. Australian and New Zealand Journal of Obstetrics and Gynaecology, 37, 279-281.
18. National Diabetes Data Group (1979) Classification and diagnosis and diabetes mellitus and other categories of glucose intolerance. Diabetes, 28, 1039-1057.
19. Odawara, M., Asano, M. & Yamashita, K. (1995) Mitochondrial gene mutations that affect the binding of the termination factor and their prevalence among Japanese diabetes mellitus. Nucleic Acids Symposium Series, 34, 237-238.
20. Pettitt, D.J., Aleck, K.A., Baird, H.R., Carraher, M.J., Bennett, P.H. & Knowler, W.C. (1988) Congenital susceptibility to NIDDM: role of intrauterine environment. Diabetes, 37, 622-628.
21. Piwernetz, K., Home, P.D., Snorgaard, O., Antsiferov, M., Staehr-Johansen, K. & Krans, M. (1993) Monitoring the targets of the St. Vincent declaration and the implementation of quality management in diabetes care: the DiabCare initiative. Diabetic Medicine, 10, 371-377.
22. Rossetti, L., Giaccari, A. & DeFronzo, R.A. (1990) Glucose toxicity. Diabetes Care, 13, 610-630.
23. Rotig, A., Bonnefont, J.P. & Munnich, A. (1996) Mitochondrial diabetes mellitus. Diabetes & Metabolism, 22, 291-298.
24. Sambrook, J., Fritsch, E.F. & Maniatis, T. (1989) Molecular cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, New York.
25. Service, F.J., Rizza, R.A., Zimmerman, B.R., Dyck, P.J., O'Brien, P.C. & Melton, L.J. (1997) The classification of diabetes by clinical and c-peptide criteria. Diabetes Care, 20, 198-201.
26. Sheu, W.H., Song, Y.M., Lee, W.J., Yao, Y.E., Lin, C.J., Tseng, L.N., Bau, C.T. & Bai, C.L. (1999) Family aggregation and maternal inheritance of Chinese type 2 diabetes mellitus in Taiwan. Chung Hua I Hsueh Tsa Chih (Taipei), 62, 146-151.
27. Shigemoto, M., Yoshimasa, Y., Yamamoto, Y., Hayashi, T., Suga, J., Inoue, G., Okamoto, M., Jingami, H., Tsuda, K., Yamamoto, T., Yagura, T., Oishi, M., Tsujii, S., Kuzuya, H. & Nakao, K. (1998) Clinical manifestations due to a point mutation of the mitochondrial tRNALeu (UUR) gene in five families with diabetes mellitus. Internal Medicine, 37, 265-272.
28. Shoffner, J.M., Lott, M.T., Lezza, A.M.S., Serbel, P., Ballinger, S.W. & Wallace, D.C. (1990) Myoclonic epilepsy and ragged-red fiber disease (MERRF) is associated with a mitochondrial DNA tRNA Lys mutation. Cell, 61, 931-937.
29. Silverman, B.L., Rizzo, T.A., Cho, N.H. & Metzger, B.E. (1998) Long-term effects of the intrauterine environment. The Northwestern University Diabetes in Pregnancy Center. Diabetes Care, 21, B142-B149.
30. Leu (UUR) A to G 3243 mutation is associated with insulin dependent and non insulin dependent diabetes in a Chinese population. Diabetic Medicine, 14, 1026-1031.
31. Lys mutation. Diabetes Care, 17, 1428-1432.
32. Leu (UUR) mutation at position 3243. Journal of Neurological Sciences, 145, 49-53.
33. 't Hart, L.M., Jansen, J.J., Lemkes, H.H., de Knijff, P. & Maassen, J.A. (1996) Heteroplasmy levels of a mitochondrial gene mutation associated with diabetes mellitus decrease in leucocyte DNA upon ageing. Human Mutation, 7, 193-197.
34. Taylor, S.I., Accili, D. & Imai, Y. (1994) Insulin resistance or insulin deficiency. Which is the primary cause of NIDDM. Diabetes, 43, 736-740.
35. Thomas, F., Balkau, B., Vazelle-Kervroedan, V., Papoz, L. & The CODIAB INSERM ZENECA Study Group. (1994) Maternal effect and familial aggregation in NIDDM. The CODIAB study. Diabetes, 43, 63-67.
36. van den Ouweland, J.M.W., Lemkes, H.H.P.J., Ruitenbeek, W., Sandkuijl, L.A., de Vijlder, M.F., Struyvenberg, P.A.A., van de Kamp, J.J.P. & Maassen, J.A. (1992) Mutation in mitochondrial tRNA (Leu) (UUR) gene in a large pedigree with maternally transmitted type II diabetes mellitus and deafness. Nature Genetics, 1, 368-371.
37. Leu (UUR) gene mutation. Diabetes, 45, 478-487.
38. Vialettes, B., Paquis-Flucklinger, V. & Bendahan, D. (1997) Clinical aspects of mitochondrial diabetes. Diabetes & Metabolism, 23, 52-56.
39. Vionnet, N., Passa, P. & Froguel, P. (1993) Prevalence of mitochondrial gene mutations in families with diabetes melllitus [Letter]. Lancet, 342, 1429-1430.
40. World Health Organization (1985) Diabetes Mellitus: Report of a WHO Study Group. WHO, Geneva.
41. Leu(UUR) gene mutation diabetes mellitus in Chinese. Chinese Medical Journal, 110, 372-378.