Could coenzyme Q10 and l-carnitine be a treatment for diabetes secondary to 3243 mutation of mtDNA?

Diabetologia

Volumn 38, Issue 12, 1995, Pages 1485-1486

  Vialettes, B ^a  

^a ASSISTANCE PUBLIQUE HÔPITAUX DE MARSEILLE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

C PEPTIDE; CARNITINE; INSULIN; UBIDECARENONE;

ADULT; CASE REPORT; FEMALE; HUMAN; LETTER; MELAS SYNDROME; MUTATION; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL;

BLOOD GLUCOSE; C-PEPTIDE; CARNITINE; CASE REPORT; DEAFNESS; DIABETES MELLITUS, NON-INSULIN-DEPENDENT; DNA, MITOCHONDRIAL; FEMALE; FOLLOW-UP STUDIES; HEMOGLOBIN A, GLYCOSYLATED; HUMAN; INSULIN; MAGNETIC RESONANCE SPECTROSCOPY; MIDDLE AGE; MITOCHONDRIA, MUSCLE; MUSCLE, SKELETAL; POINT MUTATION; RETINITIS; RNA, TRANSFER, LEU; UBIQUINONE;

EID: 0028802967     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/BF00400614     Document Type: Letter

References (16)

1. Mitochondrial gene defects in patients with NIDDM
2. Diabetes mellitus is one of the hetereogenous phenotypic features of a mitochondrial DNA point mutation within the tRNAleu(UUR) gene
3. A subtype of diabetes mellitus associated with a mutation of mitochondrial DNA
4. Mitochondrial diabetes mellitus: prevalence and clinical characterization of diabetes due to mitochondrial tRNAleu(UUR) gene mutation in Japanese patients
5. Diabetes mellitus carrying a mutation in the mitochondrial tRNA Leu(UUR) gene
6. Mitochondrial gene mutation in islet-cell antibody-positive patients who were initially non-insulin-dependent diabetics
7. Diabetes mellitus associated with a pathogenic point mutation in mitochondrial DNA
8. Adult-onset diabetes mellitus and neurosensory hearing loss in maternal relatives of MELAS patients in a family with the tRNAleu(UUR) mutation
9. Mutation in mitochondrial tRNAleu(UUR) gene in large pedigree with maternally transmitted type II diabetes mellitus and deafness
10. 31P NMR spectroscopy and ergometer exercise test as evidence for muscle oxidative preformance improvement with coenzyme Q in mitochondrial myopathies
11. Ubidecarenone in the treatement of mitochondrial myopathies: a multi-center double-blind trial
12. Mitochondrial encephalopathy (MELAS): pathological study and successful therapy with coenzyme Q10 and idebenone
13. Long-term coenzyme Q10 therapy for a mitochondrial encephalomyopathy with cytochrome c oxidase deficiency: a 31P NMR study
14. Multicenter trial with ubidecarenone: treatment of 44 patients with mitochondrial myopathies
15. Heterogeneity of metabolic response to exercise in humans: new criteria of invariance defined by in vivo phosphorus NMR spectroscopy
16. Investigation of metabolic myopathies by 31P MRS using a standardised rest-exercise-recovery protocol: a survey of 800 explorations