Interaction of Btk and Akt in B cell signaling

Biochemical and Biophysical Research Communications

Volumn 293, Issue 5, 2002, Pages 1319-1326

  Lindvall, Jessica ^a   Islam, Tahmina C ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Akt; B cells; Btk; Hydrogen peroxide; PI 3 K

Indexed keywords

BRUTON TYROSINE KINASE; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; CELL MEMBRANE; CELL NUCLEUS; CELL STIMULATION; CELL STRAIN COS7; CELLULAR DISTRIBUTION; CHICKEN; CONTROLLED STUDY; ENZYME ANALYSIS; ENZYME ASSAY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; B-LYMPHOCYTES; CELL LINE; CHICKENS; COS CELLS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; HYDROGEN PEROXIDE; IMMUNOBLOTTING; MICROSCOPY, FLUORESCENCE; OXIDATIVE STRESS; OXYGEN; PHOSPHORYLATION; PRECIPITIN TESTS; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFECTION;

GALLUS GALLUS;

EID: 0036075365     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(02)00382-0     Document Type: Article

References (46)

1. Redox-dependent signal transduction
2. Oxidants, oxidative stress and the biology of ageing
3. Is NF-kappaB the sensor of oxidative stress?
4. NF-kappa B: Ten years after
5. The Tec family of cytoplasmic tyrosine kinases: Mammalian Btk, Bmx, Itk, Tec, Txk and homologs in other species
6. The role of Bruton's tyrosine kinase in B-cell development and function: A genetic perspective
7. The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases
8. Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia
9. Colocalization of X-linked agammaglobulinemia and X-linked immunodeficiency genes
10. Mutation of unique region of Bruton's tyrosine kinase in immunodeficient XID mice
11. T cell receptor signalling
12. Molecular dissection of B cell antigen receptor signaling
13. BLNK: A central linker protein in B cell activation
14. Requirement for B cell linker protein (BLNK) in B cell development
15. An essential role for BLNK in human B cell development
16. 2-terminal kinase 1, and p38 mitogen-activated protein kinase
17. Multiple signaling pathways for the activation of JNK in mast cells: Involvement of Bruton's tyrosine kinase, protein kinase C, and JNK kinases, SEK1 and MKK7
18. Redistribution of Bruton's tyrosine kinase by activation of phosphatidylinositol 3-kinase and Rho-family GTPases
19. Phosphatidylinositol 3-kinase-dependent membrane association of the Bruton's tyrosine kinase pleckstrin homology domain visualized in single living cells
20. Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
21. Cellular survival: A play in three Akts
22. Insulin-like growth factor (IGF)-I regulates IGF-binding protein-5 gene expression through the phosphatidylinositol 3-kinase, protein kinase B/Akt, and p70 S6 kinase signaling pathway
23. Syk and Bruton's tyrosine kinase are required for B cell antigen receptor-mediated activation of the kinase Akt
24. B cell antigen receptor-induced activation of Akt promotes B cell survival and is dependent on Syk kinase
25. BTK mediated apoptosis, a possible mechanism for failure to generate high titer retroviral producer clones
26. BLNK mediates Syk-dependent Btk activation
27. Identification of phosphorylation sites for Bruton's tyrosine kinase within the transcriptional regulator BAP/TFII-I
28. Mammalian MAP kinase signalling cascades
29. Functional dissection of BCR signaling pathways
30. B Cell adaptor containing src homology 2 domain (BASH) links B cell receptor signaling to the activation of hematopoietic progenitor kinase 1
31. Effect of phosphoinositide-dependent kinase 1 on protein kinase B translocation and its subsequent activation
32. Syk is required for the activation of Akt survival pathway in B cells exposed to oxidative stress
33. Regulation of oxidative stress-induced calcium release by phosphatidylinositol 3-kinase and Bruton's tyrosine kinase in B cells
34. Phosphatidylinositol 3-kinase-gamma activates Bruton's tyrosine kinase in concert with Src family kinases
35. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
36. Insulin-stimulated protein kinase B phosphorylation on Ser473 is independent of its activity and occurs through a staurosporine-insensitive kinase
37. Akt-dependent cytokine production in mast cells
38. Bruton's tyrosine kinase links the B cell receptor to nuclear factor kappaB activation
39. Bruton's tyrosine kinase is required for activation of IkappaB kinase and nuclear factor kappaB in response to B cell receptor engagement
40. The adaptor protein BLNK is required for B cell antigen receptor-induced activation of NFk-B and cell cycle entry and survival of B lymphocytes
41. Nucleocytoplasmic shuttling of Bruton's tyrosine kinase
42. Involvement of regulatory and catalytic subunits of phosphoinositide 3-kinase in NF-kappaB activation
43. Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1
44. Phosphorylation and regulation of Raf by Akt (protein kinase B)
45. Insulin-mediated cell proliferation and survival involve inhibition of c-Jun N-terminal kinases through a phosphatidylinositol 3-kinase- and mitogen-activated protein kinase phosphatase-1-dependent pathway
46. The cellular phenotype conditions Btk for cell survival or apoptosis signaling