GTP cyclohydrolase I gene transfer augments intracellular tetrahydrobiopterin in human endothelial cells: Effects on nitric oxide synthase activity, protein levels and dimerisation

Cardiovascular Research

Volumn 55, Issue 4, 2002, Pages 838-849

  Cai, Shijie ^a   Alp, Nicholas J ^a   McDonald, Denise ^a   Smith, Ian ^a   Kay, Jonathan ^a   Canevari, Laura ^b   Heales, Simon ^b   Channon, Keith M ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Endothelial function; Gene therapy; Nitric oxide

Indexed keywords

ADENOVIRUS VECTOR; GREEN FLUORESCENT PROTEIN; GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE I; HYBRID PROTEIN; MONOMER; NITRIC OXIDE SYNTHASE; PROTEIN; RECOMBINANT ENZYME; TETRAHYDROBIOPTERIN;

ANIMAL CELL; ARTICLE; CELL LEVEL; CELL STRAIN 3T3; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIMERIZATION; ENDOTHELIUM CELL; ENDOTHELIUM LESION; ENZYME ACTIVITY; ENZYME ASSAY; GENE THERAPY; GENE TRANSFER; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS REGULATION; REGULATORY MECHANISM; VALIDATION PROCESS; VIRUS RECOMBINANT;

EID: 0036045827     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(02)00460-1     Document Type: Article

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