Structural characterization of nitric oxide synthase isoforms reveals striking active-site conservation

Nature Structural Biology

Volumn 6, Issue 3, 1999, Pages 233-242

  Fischmann, Thierry O ^a   Hruza, Alan ^a   Niu, Xiao Da ^a   Fossetta, James D ^a   Lunn, Charles A ^a   Dolphin, Edward ^a   Prongay, Andrew J ^a   Reichert, Paul ^a   Lundell, Daniel J ^a   Narula, Satwant K ^a   Weber, Patricia C ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; GLUTAMIC ACID; HEME; ISOENZYME; NITRIC OXIDE SYNTHASE; TETRAHYDROBIOPTERIN; THIOUREA DERIVATIVE;

ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME INHIBITOR COMPLEX; ENZYME SUBSTRATE COMPLEX; HYDROGEN BOND; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMALS; ARGININE; BINDING SITES; BIOPTERIN; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; ENZYME INHIBITORS; HEME; HUMANS; MICE; MOLECULAR SEQUENCE DATA; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY;

EID: 17444402500     PISSN: 10728368     EISSN: None     Source Type: Journal    
DOI: 10.1038/6675     Document Type: Article

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