Optimization of ex vivo inducible nitric oxide synthase gene transfer to vein grafts

Surgery

Volumn 126, Issue 2, 1999, Pages 323-329

  Kibbe, Melina R ^a,b,c   Nie, Suhua ^a,b   Yoneyama, Toshie ^a,b   Hatakeyama, Kazuyuki ^a,b   Lizonova, Alena ^a,b   Kovesdi, Imre ^a,b   Billiar, Timothy R ^a,b   Tzeng, Edith ^a,b  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^b GENVEC INC   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NITRIC OXIDE SYNTHASE; NITRITE; TETRAHYDROBIOPTERIN; VIRUS VECTOR;

ADENOVIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY INTIMA PROLIFERATION; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE TRANSFER; GRAFT FAILURE; INTERNAL JUGULAR VEIN; NONHUMAN; PRIORITY JOURNAL; SURGICAL TECHNIQUE; SWINE; VEIN GRAFT;

EID: 0032816117     PISSN: 00396060     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0039-6060(99)70172-8     Document Type: Article

References (20)

1. 1. Taylor LMJ, Edwards JM, Porter JM. Present status of reversed vein bypass grafting: five-year results of a modern series. J Vasc Surg 1990;11:193-205.
2. 2. Lawrie GM, Morris GCJ, Earle N. Long-term results of coronary bypass surgery: analysis of 1698 patients followed 15 to 20 years. Ann Surg 1991;213:377-85.
3. 3. Kibbe MR, Billiar TR, Tzeng E. Gene therapy and vascular disease. Adv Pharmacol 1999; 46:85-150.
4. 4. Shears LL, Kibbe MR, Murdock AD, Billiar TR, Lizonova A, Kovesdi I, et al. Efficient inhibition of intimal hyperplasia by adenovirus-mediated inducible nitric oxide synthase gene transfer to rats and pigs in vivo. J Am Coll Surg 1998;187:295-306.
5. 5. Tzeng E, Billiar TR, Robbins PD, Loftus M, Stuehr DJ. Expression of human inducible nitric oxide synthase in a tetrahydrobiopterin (H4B)-deficient cell line: H4B promotes assembly of enzyme subunits into an active dimer. Proc Natl Acad Sci U S A 1995;92:11771-5.
6. 6. Gross SS, Levi R. Tetrahydrobiopterin synthesis: an absolute requirement for cytokine-induced nitric oxide generation by vascular smooth muscle. J Biol Chem 1992;267:25722-9.
7. 7. Gross SS, Levi R, Madera A, Park KH, Vane J, Hattori Y. Tetrahydrobiopterin synthesis is induced by LPS in vascular smooth muscle and is rate-limiting for nitric oxide production. Adv Exp Med Biol 1993;338:295-300.
8. 8. Wong HR, Finder JD, Wasserloos K, Lowenstein CJ, Geller DA, Billiar TR, et al. Transcriptional regulation of iNOS by IL-1 beta in cultured rat pulmonary artery smooth muscle cells. Am J Physiol 1996;271:L166-71.
9. 9. Spink J, Cohen J, Evans TJ. The cytokine responsive vascular smooth muscle cell enhancer of inducible nitric oxide synthase: activation by nuclear factor-kappa B. J Biol Chem 1995;270:2541-7.
10. 10. Shears LL, Kawaharada N, Tzeng E, Billiar TR, Watkins SC, Kovesdi I, et al. Inducible nitric oxide synthase suppresses the development of allograft arteriosclerosis. J Clin Invest 1997;100:2035-42.
11. 11. Graham FL, Smiley J, Russell WC, Nairn R. Characteristics of a human cell line transformed by DNA from human adenovirus type 5. J Gen Virol 1977;36:59-74.
12. 12. Geller DA, Nussler AK, Di Silvio M, Lowenstein CJ, Shapiro RA, Wang SC, et al. Cytokines, endotoxin, and glucocorticoids regulate the expression of inducible nitric oxide synthase in hepatocytes. Proc Natl Acad Sci U S A 1993;90:522-6.
13. 13. Togari A, Ichinose H, Matsumoto S, Fujita K, Nagatsu T. Multiple mRNA forms of human GTP cyclohydrolase 1. Biochem Biophys Res Commun 1902;187:359-65.
14. 14. Hatakeyama K. Measurement of biopterin and the use of inhibitors of biopterin biosynthesis. In: Titheradge MA, editor. Methods in molecular biology: nitric oxide protocols. vol 100. Totowa (NJ): Humana Press Inc; 1997. p 253-66.
15. 15. Fukushima T, Nixon JC. Analysis of reduced forms of biopterin in biological tissues and fluids. Anal Biochem 1980;102:176-88.
16. 16. Hansson GK, Geng YJ, Holm J, Hardhammar P, Wennmalm A, Jennische E. Arterial smooth muscle cells express nitric oxide synthase in response to endothelial injury. J Exp Med 1994;180:733-8.
17. 17. Yan ZQ, Yokota T, Zhang W, Hansson GK. Expression of inducible nitric oxide synthase inhibits platelet adhesion and restores blood flow in the injured artery. Circ Res 1996;79:38-44.
18. 18. Tzeng E, Yoneyama T, Hatakeyama K, Shears LL, Billiar TR. Vascular inducible nitric oxide synthase gene therapy: requirement for guanosine triphosphate cyclohydrolase 1. Surgery 1996;120:315-21.
19. 19. Roelvink PW, Lizonova A, Lee JG, Li Y, Bergelson JM, Finberg RW, et al. The coxsackievirus-adenovirus receptor protein can function as a cellular attachment protein for adenovirus serotypes from subgroups A, C, D, E, and F. J Virol 1998;72:7909-15.
20. 20. Bergelson JM, Krithivas A, Celi L, Droguett G, Horwitz, MS, Wickham T, et al. The murine CAR homolog is a receptor for coxsackie B viruses and adenoviruses. J Virol 1998; 72:415-9.