Role of human cytochrome P450 (CYP) in the metabolic activation of nitrosamine derivatives: Application of genetically engineered Salmonella expressing human CYP

Drug Metabolism Reviews

Volumn 34, Issue 3, 2002, Pages 667-676

  Kamataki, Tetsuya ^a   Fujita, Ken ichi ^a   Nakayama, Kazuo ^a   Yamazaki, Yoshiyuki ^a   Miyamoto, Masami ^a   Ariyoshi, Noritaka ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Epidemiology; Lung cancer; Mutation assay; Polymorphism; Tobacco smoke

Indexed keywords

1 NITROSOPIPERIDINE; 4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANONE; ANABASINE DERIVATIVE; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 1B1; CYTOCHROME P450 2A6; CYTOCHROME P450 2C19; CYTOCHROME P450 2C8; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 2E1; CYTOCHROME P450 3A4; CYTOCHROME P450 3A5; DIETHYLNITROSAMINE; N NITROSOANABASINE; N NITROSOANATABINE; N NITROSOPYRROLIDINE; NITROSAMINE; NITROSONORNICOTINE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE FERRIHEMOPROTEIN REDUCTASE; UNCLASSIFIED DRUG; COUMARIN 7 HYDROXYLASE; COUMARIN 7-HYDROXYLASE; MIXED FUNCTION OXIDASE; UNSPECIFIC MONOOXYGENASE;

BACTERIAL STRAIN; CANCER RISK; CANCER SUSCEPTIBILITY; CHEMICAL CARCINOGENESIS; CONFERENCE PAPER; DNA POLYMORPHISM; GENETIC ENGINEERING; HOMOZYGOSITY; HUMAN; JAPAN; LUNG CANCER; LUNG CARCINOGENESIS; METABOLIC ACTIVATION; MUTAGEN TESTING; NONHUMAN; PROTEIN EXPRESSION; SALMONELLA TYPHIMURIUM; SMOKING; TOBACCO; CHEMISTRY; GENE EXPRESSION REGULATION; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETICS; LUNG TUMOR; METABOLISM; REVIEW; RISK FACTOR;

ARYL HYDROCARBON HYDROXYLASES; GENE EXPRESSION REGULATION; GENETIC ENGINEERING; GENETIC PREDISPOSITION TO DISEASE; HUMANS; JAPAN; LUNG NEOPLASMS; MIXED FUNCTION OXYGENASES; NADPH-FERRIHEMOPROTEIN REDUCTASE; NITROSAMINES; POLYMORPHISM, GENETIC; RISK FACTORS; SALMONELLA TYPHIMURIUM; TOBACCO;

EID: 0036042006     PISSN: 03602532     EISSN: None     Source Type: Journal    
DOI: 10.1081/DMR-120005668     Document Type: Conference Paper

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