Unidirectional K+ fluxes through recombinant Shaker potassium channels expressed in single Xenopus oocytes

Journal of General Physiology

Volumn 107, Issue 4, 1996, Pages 449-457

  Stampf, Per ^a   Begenisich, Ted ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; POTASSIUM CHANNEL;

ANIMAL CELL; ARTICLE; CELL MEMBRANE STEADY POTENTIAL; GENETIC RECOMBINATION; NONHUMAN; OOCYTE; POTASSIUM CURRENT; TRANSPORT KINETICS; XENOPUS;

4-AMINOPYRIDINE; ANIMALS; ION TRANSPORT; OOCYTES; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS; XENOPUS;

EID: 0030009740     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.107.4.449     Document Type: Article

References (45)

1. + channels. In Handbook of membrane channels. C. Peracchia, editor. Academic Press, San Diego. 17-28.
2. Begenisich, T., and P. De Weer. 1977. Ionic interactions in the potassium channel of squid giant axons. Nature. 269:710-711.
3. Begenisich, T. and P. De Weer. 1980. Potassium flux ratio in voltage clamped squid giant axons. Journal of General Physiology. 76: 83-98.
4. Bek, S., and E. Jacobsson. 1994. Brownian dynamics study of a multiply-occupied cation channel: Application to understanding permeation in potassium channels. Biophysical Journal. 66:1028-1038.
5. Bogusz, S., A. Boxer, and D. Busath. 1992. An SS1-SS2 β-barrel structure for the voltage-activated potassium channel. Protein Engineering. 5:285-293.
6. - channel energetically feasible? Biophysical Journal. 62:19-21.
7. Choi, K.L., C. Mossman, J. Aubé, and G. Yellen. 1993. The internal quaternary ammonium receptor site of Shaker potassium channels. Neuron. 10:533-541.
8. Connor, J.A., and C.F. Stevens. 1971 Inward and delayed outward membrane currents in isolated neural somata under voltage clamp. Journal of Physiology. 213:1-19.
9. Dascal, N. 1987. The use of Xenopus oocytes for the study of ion channels. CRC Critical Reviews in Biochemistry. 22:317-387.
10. Durrell, S.R., and H.R. Guy. 1992. Atomic scale structure and functional models of voltage-gated potassium channels. Biophysical Journal. 62:238-250.
11. Guy, H.R., and S.R. Durrell. 1994. Using sequence homology to analyze the structure and function of voltage-gated ion channel proteins. In Molecular evolution of physiological processes. D.M. Fambrough, editor. The Rockefeller University Press, New York. 197-212.
12. + channels. In Ion channels and genetic diseases. D.C. Dawson and R.A. Frizzell, editors. The Rockefeller University Press, New York, 1-16.
13. - mixtures. Journal of General Physiology. 70:269-281.
14. Heckmann, K. 1972. Single file diffusion. Biomembranes. 3:127-153.
15. + channel signature sequence. Biophysical Journal 66:1061-1067.
16. + channel. Biophysical Journal, 65:2089-2096.
17. Hille, B., and W. Schwarz. 1978. Potassium channels as multi-ion single-file pores. Journal of General Physiology. 72:409-442.
18. Hodgkin, A.L., and A.F. Huxley. 1952. Currents carried by sodium and potassium ions through the membrane of the giant axon of Loligo. Journal of Physiology. 116:449-472.
19. Hodgkin, A.L., and R.D. Keynes. 1955. The potassium permeability of a giant nerve fibre. Journal of Physiology. 128:61-88.
20. Horowicz, P., P.W. Gage, and R.S. Eisenberg. 1968. The role of electrochemical gradient in determining potassium fluxes in frog striated muscle. Journal of General Physiology. 51:193s-203s.
21. Hoshi, T., W.N. Zagotta, and R.W. Aldrich. 1990. Biophysical and molecular mechanisms of shaker potassium channel inactivation. Science. 250:533-538.
22. Kamb, A., L.E. Iverson, and M.A. Tanouye. 1987. Molecular characterization of Shaker, a Drosophila gene that encodes a potassium channel. Cell. 50:405-413.
23. + conductance switch. Biophysical Journal 62:136-144
24. Kirsch, G.E., J.M Pascual, and C. Shieh. 1995. Functional role of a conserved aspartate in the external mouth of voltage-gated potassium channels. Biophysical Journal 68:1804-1813.
25. - channel probed by sulfhydryl-specific reagents after cysteine-scanning mutagenesis. Biophysical Journal 68:900-905.
26. Levitt, D.G. 1978. Electrostatic calculations for an ion channel. I. Energy and potential profiles and interactions between ions. Biophysical Journal 22:209-219.
27. Levitt, D.G. 1986. Interpretation of biological ion channel flux data: Reaction-rate versus continuum theory. Annual Review of Biophysics and Biophysical Chemistry. 15:29-57.
28. + channel comprises part of the pore. Nature. 367:179-182.
29. Lü, Q., and C. Miller. 1995. Silver as a probe of pore-forming residues in a potassium channel. Science. 268:304-307.
30. MacKinnon, R. 1995. Pore loops: An emerging theme in ion channel structure. Neuron. 14:889-892.
31. Newland, C.F., J.P. Adelman, B.I., Tempel, and W. Almers. 1992. Repulsion between tetraethylammonium ions in cloned voltage-gated potassium channels. Neuron. 8:975-982.
32. Park, C.S., S.F. Hausdorff, and C. Miller. 1991. Design, synthesis, and functional expression of a gene for charybdotoxin, a peptide blocker of KT channels. Proceedings of the National Academy of Sciences USA. 88:2046-2050.
33. + pore structure revealed by reporter cysteines at inner and outer residues. Neuron. 14:1055-1063.
34. Patton, D.E., T. Silva, D. DiGregorio, and F. Bezamilla. 1994. Functional expression of a delayed rectifier potassium channel cloned from squid Xenopus oocytes. Biophysical Journal. 66: A105.
35. + channels. Biophysical Journal. 66:1929-1938.
36. Perri, M.A., J.J.C. Rosenthal, T. Liu, and W.F. Gilly. 1994. Cloning and distribution of KV-1 type potassium channel sequences in the squid stellate ganglia. Biophysical Journal. 66:A105.
37. + channel. Biophysical Journal. 63: 1032-1044.
38. + channel sequences from the squid Loligo pealei. Biophysical Journal. 66: A105.
39. Slesinger, P.A., Y.N. Jan, and L.Y. Jan. 1993. The S4-S5 loop contributes to the ion-selective pore of potassium channels. Neuron. 11: 739-749.
40. Spalding, B.C., O. Senyk, J.G. Swift, and P. Horowicz. 1981. Unidirectional flux ratio for potassium ions in depolarized frog skeletal muscle. American Journal of Physiology. 241:68-75.
41. Stampe, P., and T. Begenisich. 1995. The pore of Shaker K channels can simultaneously be occupied by at least three ions. Biophys. J. 68:A129. (Abstr.).
42. Tempel, B.L., D.M. Papazian, T.L. Schwarz, Y.N. Jan, and L.Y. Jan. 1987. Sequence of a probable potassium channel component encoded at Shaker locus of Drosophila. Science. 237:770-775.
43. Ussing, H.H. 1949. The distinction by means of tracers between active transport and diffusion. The transfer of iodide across the isolated frog skin. Acta Physiologica Scandinavica 19:43-56.
44. + channel of human red cells. Journal of Membrane Biology. 88:67-75.
45. Yool, A.J., and T.L. Schwarz 1991. Alteration of ionic selectivity of a channel by mutation of the H5 region. Nature. 349:700-704.