Binding of pyridostigmine bromide, N,N-diethyl-m-toluamide and permethrin, alone and in combinations, to human serum albumin

Archives of Toxicology

Volumn 76, Issue 4, 2002, Pages 203-208

  Abu Qare, Aqel W ^a,b   Abou Donia, Mohamed B ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b NeoPharm Inc   (United States)

Author keywords

Gulf War illness; Human serum albumin; N,N Diethyl m toluamide; Permethrin; Pyridostigmine bromide

Indexed keywords

DIETHYLTOLUAMIDE; HUMAN SERUM ALBUMIN; INSECT REPELLENT; INSECTICIDE; PERMETHRIN; PYRIDOSTIGMINE; CHOLINESTERASE INHIBITOR; SERUM ALBUMIN;

ARTICLE; BINDING COMPETITION; BINDING SITE; CHEMICAL ANALYSIS; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); DRUG PROTEIN BINDING; INCUBATION TIME; PRIORITY JOURNAL; PROTEIN BINDING; ANALYSIS OF VARIANCE; CHEMISTRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN;

ANALYSIS OF VARIANCE; CHOLINESTERASE INHIBITORS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEET; HUMAN; INSECT REPELLENTS; INSECTICIDES, BOTANICAL; PERMETHRIN; PROTEIN BINDING; PYRIDOSTIGMINE BROMIDE; SERUM ALBUMIN; SUPPORT, U.S. GOV'T, NON-P.H.S.; HUMANS; INSECTICIDES;

INSECTA;

EID: 0035987069     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-002-0328-8     Document Type: Article

References (60)

1. Evaluation of solid-phase microextraction for the study of protein binding in human plasma samples
2. Locomotor and sensorimotor performance deficit in rats following exposure to pyridostigmine bromide, DEET, and permethrin, alone and in combination
3. Neurotoxicity resulting from co-exposure to pyridostigmine bromide, DEET, and permethrin: Implications of Gulf War chemicals exposure
4. Simultaneous determination of pyridostigmine bromide, N,N-diethyl-m-toluamide, permethrin and metabolites in rat plasma and urine
5. Induction of urinary excretion of 3-nitrotyrosine, a marker of oxidative stress following administration of pyridostigmine bromide, DEET (N,N-diethyl-m-toluamide), and permethrin, alone and in combination in rats
6. Toxicokinetics of permethrin in the rat
7. Clinical pharmacokinetics of cholinesterase inhibitors
8. Pharmacokinetics and oral bioavailability of pyridostigmine in man
9. Binding measurements of indolocarbazole derivatives to immobilised human serum albumin by high performance liquid chromatography
10. Cocaine and cocaethylene binding in human serum
11. The relationship between pharmacokinetics, cholinesterase inhibition and facilitation of twitch tension of the quaternary ammonium anticholinesterase drugs, neostigmine, pyridostigmine, edrophonium, and 3-hydroxyphenyltrimethyl ammonium
12. 14C]pyridostigmine bromide in the rat
13. The interaction of sarin and soman with plasma proteins: The identification of a novel phosphonylation site
14. 14C-N,N-diethyl-m-toluamide in the animal body. II. Distribution and excretion after cutaneous application
15. Pyridostigmine kinetics in healthy subjects and patients with myasthenia gravis
16. Insect repellents: An overview
17. Efficacy of D-permethrin and permethrin formulations against head lice: Comparison
18. Plasma concentration of pyridostigmine and effects in myasthenia gravis
19. The pharmacokinetics of pyridostigmine
20. Microsomal metabolism of N,N-diethyl-m-toluamide (DEET, DET): The extended network of metabolites
21. Use of a human serum albumin-based high-performance liquid chromatography chiral stationary phase for the investigation of protein binding: Detection of the allosteric interaction between warfarin and benzodiazepine binding sites
22. Insect-repellent-induced toxic encephalopathy in a child
23. Effects of protein binding on the in vitro activity of antitumour acridine derivatives and related anticancer drugs
24. Treatment of myasthenia gravis
25. Permethrin: A top end viewpoint and experience
26. Characterization of the binding of digitoxin and acetyldigitoxin to human serum albumin by high-performance affinity chromatography
27. Recent advances in chromatographic and electrophoretic methods for the study of drug-protein interactions
28. 1-acid glycoprotein
29. Interactions of pyridostigmine bromide, DEET, and permethrin alter locomotor behavior of rats
30. Pyridostigmine used as a nerve agent pretreatment under wartime conditions
31. Disposition of valproic acid in maternal, fetal, and newborn sheep 1: Placental transfer, plasma protein binding, and clearance
32. Epidemiological association in US veterans between Gulf War illness and exposure to anticholinesterases
33. Acute oral toxicity study of pyridostigmine bromide, permethrin, and DEET in the laboratory rat
34. Lyme disease: National update
35. Nerve membrane ionic channels as the primary target of pyrethroid
36. Neuromuscular effects of low level exposures to Sarin, pyridostigmine, DEET, and chlorpyrifos
37. A rapid spectroflourimetric technique for determining drug-serum protein binding suitable for high-throughput screening
38. The effects of selected drugs on the in vitro protein binding of repaglinide in human plasma
39. Location of binding sites on immobilized human serum albumin for some nonsteroidal anti-inflammatory drugs
40. Review of the biodistribution and toxicity of the insect repellent N,N-diethyl-m-toluamide (DEET)
41. Toxic encephalopathy in a child after brief exposure to insect repellents
42. Absorption, distribution, metabolism, and excretion of N,N-diethyl-M-toluamide in the rat
43. Absorption, metabolism, and excretion of N,N-diethyl-m-toluamide following dermal application to human volunteers
44. Drug distribution and protein binding
45. Pyridostigmine bromide and Gulf War Syndrome
46. High-performance capillary electrophoresis/frontal analysis for the study of protein binding of a basic drug
47. High performance frontal analysis for the study of protein binding of troglitazone (CS-045) in albumin solution and in human plasma
48. Pyridostigmine metabolism in man
49. Interactive and delayed effects of pyridostigmine and physical stress on biochemical and histological changes in peripheral tissues of mice
50. Metabolism of N,N-diethyl-m-toluamide by rat liver microsomes
51. Pharmacokinetics of pyridostigmine in dogs
52. Pharmacokinetic assessment of the dermal absorption of N,N-diethyl-m-toluamide (DEET) in cattle
53. A comparison of the acute toxicity, neuropathology, and electro physiology of N,N-diethyl-m-toluamide and N,N-dimethyl-2,2-diphenylacetamide in rats
54. Elevated oxidase and esterase levels associated with permethrin tolerance in Anopheles gambiae from Kenyan villages using permethrin-impregnated rats
55. Multi-site binding of fenoprofen to human serum albumin studied by a combined technique of microdialysis with high performance liquid chromatography
56. Clinical effects of low-levels exposures to chemical warfare agents in mice and chicken
57. Effect of mobile phase composition on the binding kinetics of chiral solutes on a protein-based high-performance liquid chromatography column: Interactions of D- and L-tryptophan with immobilized human serum albumin
58. Safety and efficacy of DEET and permethrin in the prevention of arthropod attack
59. Stereoselective binding of ketoprofen enantiomers to human serum albumin studies by high-performance liquid chromatography
60. New mathematical approach for the evaluation of drug binding to human serum albumin by high performance liquid affinity chromatography