Two Active Molecular Phenotypes of the Tachykinin NK1 Receptor Revealed by G-protein Fusions and Mutagenesis

Journal of Biological Chemistry

Volumn 276, Issue 23, 2001, Pages 19793-19799

  Holst, Birgitte ^a,b   Hastrup, Hanne ^a   Raffetseder, Ute ^a   Martini, Lene ^a,b   Schwartz, Thue W ^a,b,c  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b 7TM Pharma A S   (Denmark)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANES; CONFORMATIONS; MUTAGENESIS; PROTEINS; SUBSTITUTION REACTIONS;

MOLECULAR PHENOTYPES;

BIOCHEMISTRY;

GUANINE NUCLEOTIDE BINDING PROTEIN; NEUROKININ 1 RECEPTOR; NEUROKININ A; SUBSTANCE P; TACHYKININ RECEPTOR; HYBRID PROTEIN;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING ASSAY; CELL MEMBRANE; CONTROLLED STUDY; MUTAGENESIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; SIGNAL TRANSDUCTION; AMINO ACID SEQUENCE; ANIMAL; CELL STRAIN COS1; CHEMISTRY; GENETICS; METABOLISM; MOLECULAR GENETICS;

ANIMALIA;

AMINO ACID SEQUENCE; ANIMALS; COS CELLS; GTP-BINDING PROTEINS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; PHENOTYPE; RECEPTORS, NEUROKININ-1; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION;

EID: 0035827631     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M100621200     Document Type: Article

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