Human Mismatch Repair and G·T Mismatch Binding by hMutSα in Vitro is Inhibited by Adriamycin, Actinomycin D, and Nogalamycin

Journal of Biological Chemistry

Volumn 276, Issue 13, 2001, Pages 9775-9783

  Larson, Erik D ^a   Drummond, James T ^a  

^a INDIANA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; DRUG PRODUCTS; ENZYME INHIBITION; TUMORS;

ALKYLATING AGENTS;

DNA;

ALKYLATING AGENT; ANTINEOPLASTIC AGENT; CISPLATIN; DACTINOMYCIN; DOXORUBICIN; NOGALAMYCIN; PROTEIN; PROTEIN HMUTSALPHA; UNCLASSIFIED DRUG; ANTINEOPLASTIC ANTIBIOTIC; DNA; DNA BINDING PROTEIN; ETHIDIUM; G T MISMATCH BINDING PROTEIN; G-T MISMATCH-BINDING PROTEIN; GUANOSINE; INTERCALATING AGENT; MSH2 PROTEIN, HUMAN; NUCLEIC ACID SYNTHESIS INHIBITOR; ONCOPROTEIN; PROTEIN MSH2; THYMIDINE;

ARTICLE; BASE PAIRING; CANCER RESISTANCE; CONTROLLED STUDY; DNA DAMAGE; DNA MODIFICATION; DRUG DNA INTERACTION; HUMAN; HUMAN CELL; IN VITRO STUDY; INTERCALATION COMPLEX; MISMATCH REPAIR; MOLECULAR RECOGNITION; PRIORITY JOURNAL; BASE MISPAIRING; BIOLOGICAL MODEL; DNA REPAIR; DOSE RESPONSE; DRUG ANTAGONISM; HELA CELL; KINETICS; METABOLISM; PROTEIN BINDING;

INSERTION SEQUENCES;

ALKYLATING AGENTS; ANTIBIOTICS, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS; BASE PAIR MISMATCH; DACTINOMYCIN; DNA; DNA DAMAGE; DNA REPAIR; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXORUBICIN; ETHIDIUM; GUANOSINE; HELA CELLS; HUMANS; INTERCALATING AGENTS; KINETICS; MODELS, GENETIC; MUTS HOMOLOG 2 PROTEIN; NOGALAMYCIN; NUCLEIC ACID SYNTHESIS INHIBITORS; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS; THYMIDINE;

EID: 0035971142     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M006390200     Document Type: Article

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