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Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1537, Issue 1, 2001, Pages 63-70

Investigation of the functional role of active site loop II in a hypoxanthine phosphoribosyltransferase

(4) Lee, Christian C a Medrano, Francisco J a Craig III, Sydney P a Eakin, Ann E a,b

a UNIVERSITY OF NORTH CAROLINA (United States)

b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE (United States)

Author keywords

Hypoxanthine; Loop deletion; Mutagenesis; Phosphoribosyltransferase; Transition state

Indexed keywords

AMINO ACID; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; PYROPHOSPHATE;

AFFINITY CHROMATOGRAPHY; ARTICLE; CATALYSIS; ENZYME ACTIVE SITE; ENZYME KINETICS; ENZYME PURIFICATION; ENZYME STRUCTURE; MICHAELIS CONSTANT; PHOSPHATE METABOLISM; PRIORITY JOURNAL; PROTEIN EXPRESSION; PURINE METABOLISM; REACTION ANALYSIS; SITE DIRECTED MUTAGENESIS; TRYPANOSOMA CRUZI;

ANIMALS; BINDING SITES; CATALYSIS; DIPHOSPHATES; GENE DELETION; GUANINE; HYPOXANTHINE; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; INOSINE MONOPHOSPHATE; KINETICS; MODELS, MOLECULAR; MUTATION; PHOSPHORIBOSYL PYROPHOSPHATE; TRYPANOSOMA CRUZI;

TRYPANOSOMA; TRYPANOSOMA CRUZI;

EID: 0035958675 PISSN: 09254439 EISSN: None Source Type: Journal
DOI: 10.1016/S0925-4439(01)00057-6 Document Type: Article

Times cited : (8)

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