Efficient identification of inhibitors targeting the closed active site conformation of the HPRT from Trypanosoma cruzi

Chemistry and Biology

Volumn 7, Issue 12, 2000, Pages 957-968

  Freymann, D M ^a   Wenck, M A ^a   Engel, J C ^a   Feng, J ^a   Focia, P J ^a   Eakin, A E ^a   Craig, S P ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Chagas' disease; Hypoxanthine phosphoribosyltransferase; Structure based drug design; Trypanosoma cruzi

Indexed keywords

EID: 0034521429     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-5521(00)00045-4     Document Type: Article

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