Identification of specific pore residues mediating KCNQ1 inactivation. A novel mechanism for long QT syndrome

Journal of Biological Chemistry

Volumn 276, Issue 17, 2001, Pages 13600-13605

  Seebohm, Guiscard ^a   Scherer, Constanze R ^a   Busch, Andreas E ^a   Lerche, Christian ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ELECTROPHYSIOLOGY; MAPPING; MUTAGENESIS; POTASSIUM;

PORE RESIDUES;

BIOCHEMISTRY;

ION CHANNEL; POTASSIUM CHANNEL; POTASSIUM ION; VOLTAGE GATED POTASSIUM CHANNEL; COMPLEMENTARY RNA; GLYCINE; KCNQ1 PROTEIN, HUMAN; KCNQ2 PROTEIN, HUMAN; POTASSIUM CHANNEL KCNQ; POTASSIUM CHANNEL KCNQ1; POTASSIUM CHANNEL KCNQ2; POTASSIUM CHANNEL PROTEIN I(SK); VALINE;

ANIMAL CELL; ARTICLE; HEART RATE; LONG QT SYNDROME; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; VOLTAGE CLAMP; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; ELECTROPHYSIOLOGY; GENETICS; HEART ARRHYTHMIA; HUMAN; METABOLISM; MOLECULAR GENETICS; MUTATION; OOCYTE; PATCH CLAMP; PRENATAL DEVELOPMENT; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY; TIME; XENOPUS;

ANIMALIA; MUSTELA VISON;

AMINO ACID SEQUENCE; ANIMALS; ARRHYTHMIA; ELECTROPHYSIOLOGY; GLYCINE; HUMANS; KCNQ POTASSIUM CHANNELS; KCNQ1 POTASSIUM CHANNEL; KCNQ2 POTASSIUM CHANNEL; LONG QT SYNDROME; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; OOCYTES; PATCH-CLAMP TECHNIQUES; POINT MUTATION; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; PROTEIN STRUCTURE, TERTIARY; RNA, COMPLEMENTARY; SEQUENCE HOMOLOGY, AMINO ACID; TIME FACTORS; VALINE; XENOPUS;

EID: 0035958054     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M008373200     Document Type: Article

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