Structure-Activity Relationship Studies of Melanin-concentrating Hormone (MCH)-related Peptide Ligands at SLC-1, the Human MCH Receptor

Journal of Biological Chemistry

Volumn 276, Issue 17, 2001, Pages 13554-13562

  Audinot, Valérie ^a   Beauverger, Philippe ^a   Lahaye, Chantal ^a   Suply, Thomas ^a,b   Rodriguez, Marianne ^a   Ouvry, Christine ^a   Lamamy, Véronique ^a   Imbert, Jérôme ^a   Rique, Hervé ^a   Nahon, Jean Louis ^b   Galizzi, Jean Pierre ^a   Canet, Emmanuel ^a   Levens, Nigel ^c   Fauchère, Jean Luc ^c   Boutin, Jean A ^a  

^a INSTITUT DE RECHERCHES SERVIER   (France)

^b INSTITUT DE PHARMACOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^c INSTITUT DE RECHERCHES SERVIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELLS; CLONING; HORMONES; PROTEINS;

MELANIN;

BIOCHEMISTRY;

ADENYLATE CYCLASE; CYCLIC AMP; FORSKOLIN; G PROTEIN COUPLED RECEPTOR; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); MELANIN CONCENTRATING HORMONE; MELANIN CONCENTRATING HORMONE[6-17]; SAPONIN; SULFUR 35; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG; ALANINE; CALCIUM; DISULFIDE; HORMONE RECEPTOR; HYPOPHYSIS HORMONE; HYPOTHALAMUS HORMONE; LIGAND; MCHR1 PROTEIN, HUMAN; MELANIN; MELANIN CONCENTRATING HORMONE RECEPTOR; MELANIN-CONCENTRATING HORMONE; MELANIN-CONCENTRATING HORMONE RECEPTOR; PEPTIDE; SOMATOSTATIN RECEPTOR;

ARTICLE; BRAIN; CALCIUM TRANSPORT; FEEDING BEHAVIOR; HORMONE RECEPTOR INTERACTION; HUMAN; HUMAN CELL; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; PEPTIDE ANALYSIS; PEPTIDE SYNTHESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; AMINO ACID SEQUENCE; CELL LINE; DOSE RESPONSE; GENE DELETION; GENETIC TRANSFECTION; GENETICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IC 50; KINETICS; METABOLISM; MOLECULAR GENETICS; PROTEIN BINDING; SITE DIRECTED MUTAGENESIS; TEMPERATURE;

ALANINE; AMINO ACID SEQUENCE; CALCIUM; CELL LINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CLONING, MOLECULAR; CYCLIC AMP; DISULFIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE DELETION; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HUMANS; HYPOTHALAMIC HORMONES; INHIBITORY CONCENTRATION 50; KINETICS; LIGANDS; MELANINS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PEPTIDES; PITUITARY HORMONES; PROTEIN BINDING; RECEPTORS, PITUITARY HORMONE; RECEPTORS, SOMATOSTATIN; SAPONINS; STRUCTURE-ACTIVITY RELATIONSHIP; TEMPERATURE; TRANSFECTION;

EID: 0035957992     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M010727200     Document Type: Article

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