Evidence of the involvement of p53 in γ-radiation-induced DNA repair in human lymphoblasts

International Journal of Radiation Biology

Volumn 74, Issue 2, 1998, Pages 231-238

  Mallya, S M ^a   Sikpi, M O ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; DNA REPAIR; DNA STRAND BREAKAGE; EXCISION REPAIR; GAMMA IRRADIATION; GENE FREQUENCY; HUMAN; HUMAN CELL; LYMPHOBLAST; MUTATION RATE; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

CELLS, CULTURED; CYCLOHEXIMIDE; DNA REPAIR; GAMMA RAYS; GENES, P53; HUMANS; MUTATION; PLASMIDS; RECOMBINATION, GENETIC; TIME FACTORS; TRANSFECTION; ULTRAVIOLET RAYS;

EID: 0031853407     PISSN: 09553002     EISSN: None     Source Type: Journal    
DOI: 10.1080/095530098141618     Document Type: Article

References (41)

1. AMUNDSON, S. A., XIA, F., WOLFSON, K. and LIBER, H. L., 1993, Different cytotoxic and mutagenic responses induced by X-rays in two human lymphoblastoid cell lines derived from a single donor. Mutation Research, 286, 233-241.
2. BAKALKIN, G., YAKOVLEVA, T., SELIVANOVA, G., MAGNUSSON, K. P., SZEKELY, L., KISELEVA, E., KLEIN, G., TERENIUS, L. and WIMAN, K. G., 1994, p53 binds single-stranded DNA ends and catalyzes DNA renaturation and strand transfer. Proceedings of the National Academy of Sciences, U S A, 91, 413-417.
3. BASES, R., FRANKLIN, W. A., MOY, T. and MENDEZ, F., 1992, Enhanced excision repair activity in mammalian cells after ionizing radiation. International Journal of Radiation Biology, 62, 427-441.
4. BIRNBOIM, H. C. and DOLY, J., 1979, A rapid alkaline extraction procedure for screening recombinant plasmid DNA. Nucleic Acid Research, 7, 1513-1523.
5. CLARKE, A. R., PURDIE, C. A., HARRISON, D. J., MORRIS, R. G., BIRD, C. C., HOOPER, M. L. and WYLLIE, A. H., 1993, Thymocyte apoptosis induced by p53-dependent and independent pathways. Nature, 362, 849-852.
6. DEFIAS, M. J., HANNAWALT, P. C. and SARASIN, A., 1983, Viral probes for DNA repair. Advances in Radiation Biology, 10, 1-31.
7. EL-DEIRY, W. S., TOKINO, T., VELCULESCU, V. E., LEVY, D. B., PARSONS, R., TRENT, J. M., LIN, D., MERCER, W. E., KINZLER, K. W. and VOGELSTEIN, B., 1993, WAF1, a potential mediator of p53 tumor suppression. Cell, 75, 817-825.
8. FORD, J. M. and HANAWALT, P. C., 1995, Li-Fraumeni syndrome fibroblasts homozygous for p53 mutations are deficient in global DNA repair but exhibit normal transcription-coupled repair and enhanced UV resistance. Proceedings of the National Academy of Sciences, USA, 92, 8876-8880.
9. FORNACE, A. J. JR, 1992, Mammalian genes induced by radiation; activation of genes associated with growth control. Annual Review of Genetics, 26, 507-526.
10. GOTTLIEB, T. M. and JACKSON, S. P., 1993, The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen. Cell, 72, 131-142.
11. HIRT, B., 1967, Selective extraction of polyoma DNA from infected mouse cell cultures. Journal of Molecular Biology, 20, 365-369.
12. HUTCHINSON, F., 1985, Chemical changes induced in DNA by ionizing radiation. Progress in Nucleic Acid Research and Molecular Biology, 32, 115-154.
13. ISHIZAKI, K., EJIMA, Y., MATSUNAGA, T., HARA, R., SAKAMOTO, A., IKENAGA, M., IKAWA, Y. and AIZAWA, S., 1994, Increased UV-induced SCEs but normal repair of DNA damage in p53-deficient mouse cells. International Journal of Cancer, 58, 254-257.
14. KASTAN, M. B., ONYEKWERE, O., SIDRANSKY, D., VOGELSTEIN, B. and Craig, R. W., 1991, Participation of p53 protein in the cellular response to DNA damage. Cancer Research, 51, 6304-6311.
15. KASTAN, M. B., ZHAN, Q., EL-DEIRY, W. S., CARRIER, F., JACKS, T., WALSH, W. V., PLUNKETT, B. S., VOGELSTEIN, B. and FORNACE, A. J. JR, 1992, A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia. Cell, 71, 587-597.
16. LAMB, J. R., PETIT-FRERE, C., BROUGHTON, B. C., LEHMANN, A. R. and GREEN, M. H., 1989, Inhibition of DNA replication by ionizing radiation is mediated by a transacting factor. International Journal of Radiation Biology, 56, 125-130.
17. LANE, D. P. and CRAWFORD, L. V., 1979, T antigen is bound to a host protein in SV40-transformed cells. Nature, 278, 261-263.
18. LEES-MILLER, S. P., SAKAGUCHI, K., ULLRICH, S. J., APPELLA, E. and ANDERSON, C. W., 1992, Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53. Molecular and Cellular Biology, 12, 5041-5049.
19. LITTLE, J. B., NAGASAWA, H., KENG, P. C., YU, Y. and LI, C. Y., 1995, Absence of radiation-induced G1 arrest in two closely related human lymphoblast cell lines that differ in p53 status. Journal of Biological Chemistry, 270, 11033-11036.
20. LIU, P. K., KRAUS, E., WU, T. A., STRONG, L. C. and TAINSKY, M. A., 1996, Analysis of genomic instability in Li-Fraumeni fibroblasts with germline p53 mutations. Oncogene, 12, 2267-2278.
21. LOWE, S. W., SCHMITT, E. M., SMITH, S. W., OSBORNE, B. A. and JACKS, T., 1993, p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature, 362, 847-849.
22. MANDEL., M. and HIGA, A., 1970, Calcium-dependent bacteriophage DNA infection. Journal of the Molecular Biology, 53, 154-157.
23. MCCUTCHEN, J. A. and PAGANO, J. S., 1968, Enhancement of infectivity of SV40 deoxyribonucleic acid with diethylaminoethyl dextran. Journal of the National Cancer Institute, 41, 351-357.
24. MIYASHITA, T., KRAJEWSKI, S., KRAJEWSKA, M., WANG, H. G., LIN, H. K., LIEBERMANN, D. A., HOFFMAN, B. and REED, J. C., 1994, Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo. Oncogene, 9, 1799-1805.
25. RIGAUD, O., PAPADOPOULO, D. and MOUSTACCHI, E., 1993, Decreased deletion mutations in radioadapted human lymphoblasls. Radiation Research, 133, 94-101.
26. RUNGER, T. M., POOT, M. and KRAEMKR, K. H., 1992, Abnormal processing of transfected plasmid DNA in cells from patients with ataxia telangiectasia. Mutation Research, 293, 47-54.
27. SAMSON, L. and CAIRNS, J., 1977, A new pathway for DNA repair in Escherichia Coli. Nature, 267, 281-283.
28. SANCAR, A., 1995, DNA repair in humans. Annual Review of Genetics, 29, 69-105.
29. SEIDMAN, M. M., DIXON, K., RAZZAQUE, A., ZAGURSKY, R. J. and BERMAN, M. L., 1985, A shuttle vector plasmid for studying carcinogen-induced point mutations in mammalian cells. Gene, 38, 233-237.
30. SHADLEY, J. D. and WOLFF, W., 1987, Very low doses of x-rays can cause human lymphocytes to become less susceptible to ionizing radiation. Mutagenesis, 2, 95-96.
31. SIKPI, M. O., LIU, X., LURIE, A. G. and FREEDMAN, M. L., 1994, Alteration of irradiated shuttle vector processing by exposure of human lymphoblast host cells to single or split gamma-ray doses. International Journal of Radiation Biology, 65, 157-164.
32. SIKPI, M. O., WANG, Y and MALIYA S. M. Defective gamma-radiation modulation of double strand break repair in ataxia telangiectasia cells. Radiation Research, in press.
33. SMITH, M. L., CHEN, I. T., ZHAN, Q., BAE, I., CHEN, C. Y., GILMER, T. M., KASTAN, M. B., O'CONNOR, P. M. and FORNACE, A. J. JR, 1994, Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen. Science, 266, 1376-1380.
34. SMITH, M. L., CHEN, I. T., ZHAN, Q., O'CONNOR, P. M. and FORNACE, A. J. JR, 1995, Involvement of the p53 tumor suppressor in repair of u.v.-type DNA damage. Oncogene, 10, 1053-1059.
35. STRAIN, A. J. and WYLLIE, A. H., 1984, The uptake and stability of simian-virus-40 UNA after calcium phosphate transfection of CV-1 cells. Biochemical Journal, 218, 475-482.
36. STURZBECHER, H. W., DONZELMANN, B., HENNING, W., KNIPPSCHILD, U. and BUCHHOP, S., 1996, p53 is linked directly to homologous recombination processes via RAD51/RecA protein interaction. EMBO Journal, 15, 1992-2002.
37. WANG, Y., HUQ, M. S. and ILIAKIS, G., 1996, Evidence for activities inhibiting in trans initiation of DNA replication in extract prepared from irradiated cells. Radiation Research, 145, 408-418.
38. WANG, X. W., YEH, H., SCHAEFFER, L., et al., 1995, p53 modulation of TFIIH-associated nucleotide excision repair activity. Nature Genetics, 10, 188-195.
39. WARD, J. F., 1988, DNA damage produced by ionizing radiation in mammalian cells: identities, mechanisms of formation, and repairability. Progress in Nucleic Acid Research and Molecular Biology, 35, 95-125.
40. WILSON, R. E., TAYLOR, S. L., ATHERTON, G. T., JOHNSTON, D., WATERS, C. M. and NORTON, J. D., 1993, Early response gene signalling cascades activated by ionising radiation in primary human B cells. Oncogene, 8, 3229-3237.
41. YU, Y., LI, C. Y. and LITTLE, J. B., 1997, Abrogation of p53 function by HPV16 E6 gene delays apoptosis and enhances mutagenesis but does not alter radiosensitivity in TK6 human lymphoblast cells. Oncogene, 14, 1661-1667.