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Volumn 32, Issue 1, 1998, Pages 33-38

Nutritional folate deficiency augments the in vivo mutagenic and lymphocytotoxic activities of alkylating agents

Author keywords

Alkylating agent; Folic acid; HPRT; Immunosuppression; Lymphocytes

Indexed keywords

ALKYLATING AGENT; CYCLOPHOSPHAMIDE; ETHYLNITROSOUREA; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE;

EID: 0031902247     PISSN: 08936692     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2280(1998)32:1<33::AID-EM4>3.0.CO;2-C     Document Type: Article
Times cited : (16)

References (29)
  • 1
    • 0025765309 scopus 로고
    • Induction of 6-thioguanine-resistant lymphocytes in Fischer 344 rats following in vivo exposure to N-ethyl-N-nitrosurea and cyclophosphamide
    • Aidoo A, Lyn-Cook LE, Mittelstaedt RA, Heflich RH, Casciano DA (1991):Induction of 6-thioguanine-resistant lymphocytes in Fischer 344 rats following in vivo exposure to N-ethyl-N-nitrosurea and cyclophosphamide. Environ Mol Mutagen 17:141-151.
    • (1991) Environ Mol Mutagen , vol.17 , pp. 141-151
    • Aidoo, A.1    Lyn-Cook, L.E.2    Mittelstaedt, R.A.3    Heflich, R.H.4    Casciano, D.A.5
  • 2
    • 0027397165 scopus 로고
    • The effect of time after treatment, treatment schedule and animal age on the frequency of 6-thioguanine-resistant T-lymphocytes induced in Fischer 344 rats by N-ethyl-N-nitrosurea
    • Aidoo A, Lyn-Cook LE, Heflich RH, George EO, Casciano DA (1993):The effect of time after treatment, treatment schedule and animal age on the frequency of 6-thioguanine-resistant T-lymphocytes induced in Fischer 344 rats by N-ethyl-N-nitrosurea. Mutat Res 298:169-178.
    • (1993) Mutat Res , vol.298 , pp. 169-178
    • Aidoo, A.1    Lyn-Cook, L.E.2    Heflich, R.H.3    George, E.O.4    Casciano, D.A.5
  • 3
    • 0025288239 scopus 로고
    • Distribution of methyl and ethyl adducts following alkylation with monofunctional alkylating agents
    • Beranek DT (1990):Distribution of methyl and ethyl adducts following alkylation with monofunctional alkylating agents. Mutat Res 231:11-30.
    • (1990) Mutat Res , vol.231 , pp. 11-30
    • Beranek, D.T.1
  • 5
    • 0025081325 scopus 로고
    • Characterization of repair inhibition by methotrexate of ethylmethanesulfonate and ultraviolet irradiation-induced DNA damage in Chinese hamster cells
    • Borchers AH, Straw JA (1990):Characterization of repair inhibition by methotrexate of ethylmethanesulfonate and ultraviolet irradiation-induced DNA damage in Chinese hamster cells. Biochem Pharmacol 40:1925-1928.
    • (1990) Biochem Pharmacol , vol.40 , pp. 1925-1928
    • Borchers, A.H.1    Straw, J.A.2
  • 6
    • 0027383695 scopus 로고
    • Folate deficiency increases genetic damage caused by alkylating agents and γ-irradiation in Chinese hamster ovary cells
    • Branda RF, Blickensderfer DB (1993):Folate deficiency increases genetic damage caused by alkylating agents and γ-irradiation in Chinese hamster ovary cells. Cancer Res 53:5401-5408.
    • (1993) Cancer Res , vol.53 , pp. 5401-5408
    • Branda, R.F.1    Blickensderfer, D.B.2
  • 7
    • 0026350934 scopus 로고
    • Factors influencing mutation at the hprt locus in T-lymphocytes:Women treated for breast cancer
    • Branda RF, O'Neill JP, Sullivan LM, Albertini RJ (1991):Factors influencing mutation at the hprt locus in T-lymphocytes:Women treated for breast cancer. Cancer Res 51:6603-6607.
    • (1991) Cancer Res , vol.51 , pp. 6603-6607
    • Branda, R.F.1    O'Neill, J.P.2    Sullivan, L.M.3    Albertini, R.J.4
  • 8
    • 0030737723 scopus 로고    scopus 로고
    • Effect of folate deficiency on mutations at the hprt locus in Chinese hamster ovary cells exposed to monofunctional alkylating agents
    • Branda RF, Lafayette AR, O'Neill JP, Nicklas JA (1997):Effect of folate deficiency on mutations at the hprt locus in Chinese hamster ovary cells exposed to monofunctional alkylating agents. Cancer Res 57:2586-2588.
    • (1997) Cancer Res , vol.57 , pp. 2586-2588
    • Branda, R.F.1    Lafayette, A.R.2    O'Neill, J.P.3    Nicklas, J.A.4
  • 9
    • 0024831011 scopus 로고
    • Repletion of folate-depleted rats with an amino acid based diet supplemented with folic acid
    • Clifford AJ, Wilson DS, Bills ND (1989):Repletion of folate-depleted rats with an amino acid based diet supplemented with folic acid. J Nutr 119:1956-1961.
    • (1989) J Nutr , vol.119 , pp. 1956-1961
    • Clifford, A.J.1    Wilson, D.S.2    Bills, N.D.3
  • 10
  • 11
    • 0027992355 scopus 로고
    • Folate and cancer:A review of the literature
    • Glynn SA, Albanes D (1994):Folate and cancer:A review of the literature. Nutr Cancer 22:101-119.
    • (1994) Nutr Cancer , vol.22 , pp. 101-119
    • Glynn, S.A.1    Albanes, D.2
  • 13
    • 0022548615 scopus 로고
    • Detection of somatic mutations in man:Evaluation of the microtitre cloning assay for T-lymphocytes
    • Henderson LH, Cole H, Cole J, Elizabeth James S, Green M (1986):Detection of somatic mutations in man:Evaluation of the microtitre cloning assay for T-lymphocytes. Mutagenesis 1:195-200.
    • (1986) Mutagenesis , vol.1 , pp. 195-200
    • Henderson, L.H.1    Cole, H.2    Cole, J.3    Elizabeth James, S.4    Green, M.5
  • 14
    • 0030694580 scopus 로고    scopus 로고
    • Induction of DNA crosslinks and DNA strand lesions by cyclophosphamide after activation by cytochrome P450 2B1
    • Hengstler JG, Hengst A, Fuchs J, Tanner B, Pohl J, Oesch F (1997):Induction of DNA crosslinks and DNA strand lesions by cyclophosphamide after activation by cytochrome P450 2B1. Mutat Res 373:215-223.
    • (1997) Mutat Res , vol.373 , pp. 215-223
    • Hengstler, J.G.1    Hengst, A.2    Fuchs, J.3    Tanner, B.4    Pohl, J.5    Oesch, F.6
  • 17
    • 0014748149 scopus 로고
    • Drug-induced immunologic tolerance:Site of action of cyclophosphamide
    • Many A, Schwartz RS (1970):Drug-induced immunologic tolerance:Site of action of cyclophosphamide. Proc Soc Exp Biol Med 133:754-757.
    • (1970) Proc Soc Exp Biol Med , vol.133 , pp. 754-757
    • Many, A.1    Schwartz, R.S.2
  • 18
    • 0030277195 scopus 로고    scopus 로고
    • Folate:Effects on carcinogenesis and the potential for cancer chemoprevention
    • Mason JB, Levesque T (1996):Folate:Effects on carcinogenesis and the potential for cancer chemoprevention. Oncology 10:1727-1743.
    • (1996) Oncology , vol.10 , pp. 1727-1743
    • Mason, J.B.1    Levesque, T.2
  • 19
    • 0029417250 scopus 로고
    • Analysis of in vivo mutation induced by N-ethyl-N-nitrosurea in the hprt gene of rat lymphocytes
    • Mittelstaedt RA, Smith BA, Heflich RH (1995):Analysis of in vivo mutation induced by N-ethyl-N-nitrosurea in the hprt gene of rat lymphocytes. Environ Mol Mutagen 26:261-269.
    • (1995) Environ Mol Mutagen , vol.26 , pp. 261-269
    • Mittelstaedt, R.A.1    Smith, B.A.2    Heflich, R.H.3
  • 20
    • 0019400045 scopus 로고
    • Effects of dietary folate, vitamin B12 and methionine/choline deficiency on immune function
    • Nauss KM, Newberne PM (1981):Effects of dietary folate, vitamin B12 and methionine/choline deficiency on immune function. Adv Exp Med Biol 135:63-91.
    • (1981) Adv Exp Med Biol , vol.135 , pp. 63-91
    • Nauss, K.M.1    Newberne, P.M.2
  • 21
    • 0023131909 scopus 로고
    • Refinement of a T-lymphocyte cloning assay to quantify the in vivo thioguanine-resistant mutant frequency in humans
    • O'Neill JP, McGinniss MJ, Berman JK, Sullivan LM, Nicklas JA, Albertini RF (1987):Refinement of a T-lymphocyte cloning assay to quantify the in vivo thioguanine-resistant mutant frequency in humans. Mutagenesis 2:87-94.
    • (1987) Mutagenesis , vol.2 , pp. 87-94
    • O'Neill, J.P.1    McGinniss, M.J.2    Berman, J.K.3    Sullivan, L.M.4    Nicklas, J.A.5    Albertini, R.F.6
  • 22
    • 0028925741 scopus 로고
    • Breaks in genomic DNA and within the p53 gene are associated with hypomethylation in livers of folate/methyl-deficient rats
    • Pogribny IP, Basnakian AG, Miller BJ, Lopalina NG, Poirier LA, James SJ (1995):Breaks in genomic DNA and within the p53 gene are associated with hypomethylation in livers of folate/methyl-deficient rats. Cancer Res 55:1894-1901.
    • (1995) Cancer Res , vol.55 , pp. 1894-1901
    • Pogribny, I.P.1    Basnakian, A.G.2    Miller, B.J.3    Lopalina, N.G.4    Poirier, L.A.5    James, S.J.6
  • 23
    • 0025074703 scopus 로고
    • Procarbazine carcinogenicity in methotrexate-treated or lipotrope-deficient male rats
    • Rogers AE, Akhtar R, Zeisel SH (1990):Procarbazine carcinogenicity in methotrexate-treated or lipotrope-deficient male rats. Carcinogenesis 11:1491-1495.
    • (1990) Carcinogenesis , vol.11 , pp. 1491-1495
    • Rogers, A.E.1    Akhtar, R.2    Zeisel, S.H.3
  • 24
    • 0030591653 scopus 로고    scopus 로고
    • Mutagenic damage to mammalian cells by therapeutic alkylating agents
    • Sanderson BJS, Shield AJ (1996):Mutagenic damage to mammalian cells by therapeutic alkylating agents. Mutat Res 355:41-57.
    • (1996) Mutat Res , vol.355 , pp. 41-57
    • Sanderson, B.J.S.1    Shield, A.J.2
  • 25
    • 0000746151 scopus 로고
    • Microbiological assays of folates
    • Picciano MF, Stokstad EL, Gregory JF (eds). New York:Wiley-Liss
    • Tamura T (1990):Microbiological assays of folates. In:Picciano MF, Stokstad EL, Gregory JF (eds):"Folic Acid Metabolism in Health and Disease." New York:Wiley-Liss, pp 121-137.
    • (1990) Folic Acid Metabolism in Health and Disease , pp. 121-137
    • Tamura, T.1
  • 26
    • 0018356390 scopus 로고
    • The relation between reaction kinetics and mutagenic action of mono-functional alkylating agents in higher eukaryotic systems. I. Recessive lethal mutations and translocations in Drosophila
    • Vogel E, Natarajan AT (1979):The relation between reaction kinetics and mutagenic action of mono-functional alkylating agents in higher eukaryotic systems. I. Recessive lethal mutations and translocations in Drosophila. Mutat Res 62:51-100.
    • (1979) Mutat Res , vol.62 , pp. 51-100
    • Vogel, E.1    Natarajan, A.T.2
  • 27
    • 0027952799 scopus 로고
    • The subtlety of alkylating agents in reactions with biological macromolecules
    • Vogel EW, Nivard MJM (1994):The subtlety of alkylating agents in reactions with biological macromolecules. Mutat Res 305:13-32.
    • (1994) Mutat Res , vol.305 , pp. 13-32
    • Vogel, E.W.1    Nivard, M.J.M.2
  • 28
    • 0023719696 scopus 로고
    • Folate deficiency in rats fed diets containing free amino acids or intact proteins
    • Walzem RL, Clifford AJ (1988):Folate deficiency in rats fed diets containing free amino acids or intact proteins. J Nutr 118:1089-1096.
    • (1988) J Nutr , vol.118 , pp. 1089-1096
    • Walzem, R.L.1    Clifford, A.J.2
  • 29
    • 0020074927 scopus 로고
    • Use of glycerol-cryoprotected Lactobacillus casei for microbiological assay of folic acid
    • Wilson SD, Home DW (1982):Use of glycerol-cryoprotected Lactobacillus casei for microbiological assay of folic acid. Clin Chem 28:1198-1200.
    • (1982) Clin Chem , vol.28 , pp. 1198-1200
    • Wilson, S.D.1    Home, D.W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.