LDL downregulates CYP51 in porcine vascular endothelial cells and in the arterial wall through a sterol regulatory element binding protein-2-dependent mechanism

Circulation Research

Volumn 88, Issue 3, 2001, Pages 268-274

  Rodríguez, Cristina ^a   Martínez González, José ^a   Sánchez Gómez, Sonia ^a   Badimon, Lina ^a  

^a INST D INVESTIGACIONS B   (Spain)

Author keywords

CYP51; Endothelium; Hypercholesterolemia; LDL; SREBP 2

Indexed keywords

CYCLOHEXIMIDE; CYTOCHROME P450; LOW DENSITY LIPOPROTEIN; N ACETYLLEUCYLLEUCYLNORLEUCINAL; STEROL 14ALPHA DEMETHYLASE; STEROL REGULATORY ELEMENT BINDING PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ABDOMINAL AORTA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY WALL; ARTICLE; ATHEROSCLEROSIS; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; ENDOTHELIUM CELL; FEMALE; GENE CONTROL; HYPERCHOLESTEROLEMIA; LIPID METABOLISM; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SWINE; VASCULAR ENDOTHELIUM;

EID: 0035895677     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.88.3.268     Document Type: Article

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