Growth factor activity of endothelin-1 in primary astrocytes mediated by adhesion-dependent and -independent pathways

Journal of Neuroscience

Volumn 17, Issue 16, 1997, Pages 6203-6212

  Cazaubon, Sylvie ^a   Chaverot, Nathalie ^a   Romero, Ignacio A ^a   Girault, Jean Antoine ^b   Adamson, Peter ^c   Strosberg, A Donny ^a   Couraud, Pierre Olivier ^a  

^a INSTITUT COCHIN   (France)

^b l'alimentation et l'Environnement   (France)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Cell adhesion; Endothelin 1; Extracellular signal regulated kinase; Focal adhesion kinase; Growth factor; Primary astrocyte; Stress fibers

Indexed keywords

ENDOTHELIN 1; GROWTH FACTOR;

ANIMAL CELL; ARTICLE; ASTROCYTE; CELL ADHESION; CELL GROWTH; CYTOSKELETON; EXTRACELLULAR MATRIX; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

EID: 0030753892     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.17-16-06203.1997     Document Type: Article

References (29)

1. Cazaubon SM, Couraud PO (1997) Nitric oxide and endothelin at the blood-brain barrier. In: An introduction to the blood-brain barrier (Pardridge WM, ed). Cambridge: Cambridge UP, in press.
2. Cazaubon SM, Ramos-Morales F, Fischer S, Schweighoffer F, Strosberg AD, Couraud PO (1994) Endothelin induces tyrosine phosphorylation and GRB2 association of SHC in astrocytes. J Biol Chem 269:24805-24809.
3. Cazaubon S, Parker PJ, Strosberg AD, Couraud PO (1993) Endothelins stimulate phosphorylation and activity of p42/mitogen-activated protein kinase in astrocytes. Biochem J 293:381-386.
4. Cobb BS, Schaller MD, Leu TH, Parsons JT (1994) Stable association of pp60src and pp59fyn with the focal adhesion-associated protein tyrosine kinase, pp125FAK. Mol Cell Biol 14:147-155.
5. Couraud PO, Durieu-Trautmann O, Le Nguyen P, Marin P, Gilbert F, Strosberg AD (1991) Functional endothelin-1 receptors in rat astrocytoma C6. Eur J Pharmacol 206:191-198.
6. Craig SW, Johnson R (1996) Assembly of focal adhesions: progress, paradigms, and portents. Curr Opin Cell Biol 8:74-85.
7. Durieu-Trautmann O, Fédérici C, Créminon C, Foignant-Chaverot N, Roux F, Claire M, Strosberg AD, Couraud PO (1993) Nitric oxide and endothelin secretion by microvessel endothelial cells: regulation by cyclic nucleotides. J Cell Physiol 155:104-111.
8. Durieu-Trautmann O, Chaverot N, Cazaubon S, Strosberg AD, Couraud PO (1994) ICAM-1 activation induces tyrosine phosphorylation of the cytoskeleton-associated protein cortactin in brain microvessel endothelial cells. J Biol Chem 269:12536-12540.
9. Fath I, Schweighoffer F, Rey I, Multon MC, Boiziau J, Duchesne M, Tocque B (1994) Cloning of a Grb2 isoform with apoptotic properties. Science 264:971-974.
10. Hotchin NA, Hall A (1995) The assembly of integrin adhesion complexes requires both extracellular matrix and intracellular rho/rac GT-Pases. J Cell Biol 131:1857-1865.
11. Ladenheim R, Lacroix I, Foignant-Chaverot N, Strosberg AD, Couraud PO (1993) Endothelins stimulate c-fos and nerve growth factor expression in astrocytes and astrocytoma. J Neurochem 60:260-266.
12. B endothelin receptor to mitogen-activated protein kinase stimulation and DNA synthesis in primary cultures of rat astrocytes. J Neurochem 66:459-465.
13. 2+-induced regulation of ion channel and MAP kinase functions. Science 376:737-745.
14. Luttrell LM, Hawes BE, van Biesen T, Luttrell DK, Lansing TJ, Lefkowitz RJ (1996) Role of c-Src tyrosine kinase in G-protein-coupled receptor- and Gβγ subunit-mediated activation of mitogen-activated protein kinases. J Biol Chem 271:19443-19450.
15. MacCumber MW, Ross CA, Snyder SH (1990) Endothelin in brain: receptors, mitogenesis, and biosynthesis in glial cells. Proc Natl Acad Sci USA 87:2359-2363.
16. Menter DG, Herrmann JL, Nicolson GL (1995) The role of trophic factors and autocrine/paracrine growth factors in brain metastasis. Clin Exp Metastasis 13:67-88.
17. erk-2. J Biol Chem 270:269-273.
18. Paulus W, Tonn JC (1995) Interactions of glioma cells and extracellular matrix. J Neurooncol 24:87-91.
19. Richardson A, Parsons JT (1995) Signal transduction through integrins: a central role for focal adhesion kinase? BioEssays 17:229-236.
20. ras via the tyrosine kinase-Shc-Grb2-SOS pathway in cardiac myocytes. EMBO J 15:775-787.
21. Sakurai T, Yanagisawa M, Takuwa Y, Miyazaki H, Kimura S, Goto K, Masaki T (1990) Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor. Nature 348:732-735.
22. Schaller MD, Parsons JT (1994) Focal adhesion kinase and associated proteins. Curr Biol 6:705-710.
23. Schlaepfer DD, Hanks SK, Hunter T, van der Geer P (1994) Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase. Nature 372:786-791.
24. Seger R, Krebs EG (1995) The MAPK signaling cascade. FASEB J 9:726-735.
25. FAK in platelets requires coordinated signaling through integrin and agonist receptors. J Biol Chem 269:14738-14745.
26. Tawil N, Wilson P, Carbonetto S (1993) Integrins in point contacts mediate cell spreading: factors that regulate integrin accumulation in point contacts vs. focal contacts. J Cell Biol 120:261-271.
27. Wan Y, Kurosaki T, Huang X-Y (1996) Tyrosine kinases in activation of the MAP kinase cascade by G-protein-coupled receptors. J Biol Chem 380:541-544.
28. Wary K, Mainiero F, Isakoff S, Marcantonio E, Giancotti F (1996) The adaptor protein Shc couples a class of integrins to the control of cell cycle progression. Cell 87:733-743.
29. B receptor aggregate in rat hippocampus CA1 subfields following transient forebrain ischemia. J Neurochem 63:1042-1051.