Life's 24-hour clock: Molecular control of circadian rhythms in animal cells

Trends in Biochemical Sciences

Volumn 25, Issue 12, 2000, Pages 601-606

  Young, Michael W ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN; RNA;

ANIMAL BEHAVIOR; CIRCADIAN RHYTHM; DROSOPHILA; ENVIRONMENTAL FACTOR; GENE FUNCTION; GENE MUTATION; HUMAN; MAMMAL; MOLECULAR DYNAMICS; NEUROSPORA; NONHUMAN; PRIORITY JOURNAL; REVIEW; SLEEP WAKING CYCLE; SPECIES DIFFERENCE;

ANIMALS; BEHAVIOR, ANIMAL; CIRCADIAN RHYTHM; DARKNESS; DROSOPHILA; DROSOPHILA PROTEINS; INSECT PROTEINS; MAMMALS; MUTATION; NUCLEAR PROTEINS;

ANIMALIA; MAMMALIA; NEUROSPORA;

EID: 0034423409     PISSN: 09680004     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0004(00)01695-9     Document Type: Review

References (50)

1. The search for the biochemical clock
2. Regulation of circadian rhythmicity
3. The molecular control of circadian behavioral rhythms and their entrainment in Drosophila
4. Molecular bases for circadian clocks
5. Isolation and analysis of six timeless alleles that cause short- or long-period circadian rhythms in Drosophila
6. Time flies for Drosophila
7. PER and TIM inhibit the DNA binding activity of a Drosophila CLOCK-CYC-dBMAL1 heterodimer without disrupting formation of the heterodimer: A basis for circadian transcription
8. A TIMELESS-independent function for PERIOD proteins in the Drosophila clock
9. A role for the proteasome in the light response of the TIMELESS clock protein
10. Cryptochromes: Blue light receptors for plants and animals
11. CRYPTOCHROME: The second photoactive pigment in the eye and its role in circadian photoreception
12. The cryb mutation identifies cryptochrome as a circadian photoreceptor in Drosophila
13. Light-dependent sequestration of TIMELESS by CRYPTOCHROME
14. A unique circadian-rhythm photoreceptor
15. Double-time is a novel Drosophila clock gene that regulates PERIOD protein accumulation
16. The Drosophila clock gene double-time encodes a protein closely related to human casein kinase Ie
17. Vitamin B2-based blue-light photoreceptors in the retinohypothalamic tract as the photoactive pigments for setting the circadian clock in mammals
18. mCRY1 and mCRY2 are essential components of the negative limb of the circadian clock feedback loop
19. The mPer2 gene encodes a functional component of the mammalian circadian clock
20. Interacting molecular loops in the mammalian circadian clock
21. Photic induction of mPer1 and mPer2 in cry-deficient mice lacking a biological clock
22. Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms
23. Light-independent role of CRY1 and CRY2 in the mammalian circadian clock
24. A time-less function for mouse timeless
25. A second timeless gene in Drosophila shares greater sequence similarity with mammalian tim
26. Analysis of clock proteins in mouse SCN demonstrates phylogenetic divergence of the circadian clockwork and resetting mechanisms
27. Dimerization and nuclear entry of mPER proteins in mammalian cells
28. Circadian regulation of a Drosophila homolog of the mammalian Clock gene: PER and TIM function as positive regulators
29. Interlocked feedback loops within the Drosophila circadian oscillator
30. A mutation of the circadian system in golden hamsters
31. Positional syntenic cloning and functional characterization of the mammalian circadian mutation tau
32. Nuclear entry of the circadian regulator mPER1 is controlled by mammalian casein kinase Ie
33. Phosphorylation and destabilization of human period I clock protein by human casein kinase Ie
34. Transplanted Drosophila excretory tubules maintain circadian clock cycling out of phase with the host
35. Resetting central and peripheral circadian oscillators in transgenic rats
36. Light acts directly on organs and cells in culture to set the vertebrate circadian clock
37. A serum shock induces circadian gene expression in mammalian tissue culture cells
38. Circadian rhythms in olfactory responses of Drosophila melanogaster
39. The Drosophila takeout gene is a novel molecular link between circadian rhythms and feeding behavior
40. Differential regulation of circadian pacemaker output by separate clock genes in Drosophila
41. A pdf neuropeptide gene mutation and ablation of PDF neurons each cause severe abnormalities of behavioral circadian rhythms in Drosophila
42. Pigment-dispersing hormone shifts the phase of the circadian pacemaker of the cockroach Leucophaea maderae
43. Ectopic expression of the neuropeptide pigment-dispersing factor alters behavioral rhythms in Drosophila melanogaster
44. Cycling vrille expression is required for a functional Drosophila clock
45. A molecular mechanism regulating rhythmic output from the suprachiasmatic circadian clock
46. Microbial circadian oscillatory systems in Neurospora and Synechococcus: Models for cellular clocks
47. The circadian clock of cyanobacteria
48. Circadian programs in cyanobacteria: Adaptiveness and mechanism
49. CLOCK, an essential pacemaker component, controls expression of the circadian transcription factor DBP
50. Role of DBP in the circadian oscillatory mechanism