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Volumn 89, Issue 2-3, 2001, Pages 119-128

Characterization of the molecular motions of constitutively active G protein-coupled receptors for parathyroid hormone

Author keywords

Constitutively active receptors; Coupling of G proteins to PTH receptor; G protein coupled receptors; Parathyroid hormone; PTH receptor; Structure intracellular loop 3

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; PARATHYROID HORMONE; PARATHYROID HORMONE RECEPTOR;

EID: 0035865532     PISSN: 03014622     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-4622(00)00222-2     Document Type: Article
Times cited : (14)

References (58)
  • 4
    • 0026598246 scopus 로고
    • Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide from rat osteoblast-like cells: a single receptor stimulates intracellular accumulation of both cAMP and inositol trisphosphates and increases intracellular free calcium
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 2732-2736
    • Abou-Samra, A.B.1    Jüppner, H.2    Force, T.3
  • 9
    • 0031442990 scopus 로고    scopus 로고
    • Targeted expression of constitutively active receptors for parathyroid hormone and parathyroid hormone-related peptide delays endochondral bone formation and rescues mice that lack parathyroid hormone-related peptide
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 13689-13694
    • Schipani, E.1    Lanske, B.2    Hunzelman, J.3
  • 22
    • 0006041527 scopus 로고    scopus 로고
    • D. van der Spoel, A.R. van Buuren, E. Apol et al., Gromacs User Manual, University of Groningen, 1996.
  • 23
    • 0029791008 scopus 로고    scopus 로고
    • Normal-mode analysis suggests important flexibility between the two N-terminal domains of CD4 and supports the hypothesis of a conformational change in CD4 upon HIV binding
    • (1996) Protein Eng. , vol.9 , pp. 671-677
    • Sanejouand, Y.H.1
  • 26
    • 0032879688 scopus 로고    scopus 로고
    • The functional microdomain in transmembrane helices 2 and 7 regulates expression, activation, and coupling pathways of the gonadotropin-releasing hormone receptor
    • (1999) J. Biol. Chem. , vol.274 , pp. 28880-28886
    • Flanagan, C.A.1    Zhou, W.2    Chi, L.3
  • 29
    • 0033615522 scopus 로고    scopus 로고
    • The N terminus of Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor is necessary for high affinity chemokine binding but not for constitutive activity
    • (1999) J. Biol. Chem. , vol.274 , pp. 31327-31332
    • Ho, H.H.1    Du, D.2    Gershengorn, M.C.3
  • 34
    • 0006115516 scopus 로고    scopus 로고
    • Q. Ren, H. Kurose, R.J. Lefkowitz, S. Cotecchia, Constitutively active mutants of the alpha 2-adrenergic receptor [published erratum appears in J. Biol. Chem. 1994 Jan 14;269(2):1566], J. Biol. Chem. 268 (1993) 16483-16487.
  • 35
    • 0027250914 scopus 로고
    • Substitutions of different regions of the third cytoplasmic loop of the thyrotropin (TSH) receptor have selective effects on constitutive, TSH-, and TSH receptor autoantibody-stimulated phosphoinositide and 3′,5′-cyclic adenosine monophosphate signal generation
    • (1993) Mol. Endocrinol. , vol.7 , pp. 1009-1020
    • Kosugi, S.1    Okajima, F.2    Ban, T.3    Hidaka, A.4    Shenker, A.5    Kohn, L.D.6
  • 38
    • 0028361809 scopus 로고
    • Chimeric muscarinic cholinergic:beta-adrenergic receptors that are functionally promiscuous among G proteins
    • (1994) J. Biol. Chem. , vol.269 , pp. 18968-18976
    • Wong, S.K.1    Ross, E.M.2
  • 40
    • 0033048623 scopus 로고    scopus 로고
    • A conserved arginine in the distal third intracellular loop of the mu-opioid receptor is required for G protein activation
    • (1999) J. Neurochem. , vol.72 , pp. 1307-1314
    • Wang, H.L.1
  • 42
    • 4244146179 scopus 로고    scopus 로고
    • American Society for Bone and Mineral Research, vol. 23, San Francisco: Elsevier
    • (1998)
    • Komatsu, Y.1    Segre, G.V.2
  • 46
    • 0031790855 scopus 로고    scopus 로고
    • A conserved tyrosine residue (Y601) in transmembrane domain 5 of the human thyrotropin receptor serves as a molecular switch to determine G-protein coupling
    • (1998) FASEB J. , vol.12 , pp. 1461-1471
    • Biebermann, H.1    Schoneberg, T.2    Schulz, A.3
  • 53
    • 0030895863 scopus 로고    scopus 로고
    • Mutations in the second cytoplasmic loop of the rat parathyroid hormone (PTH)/PTH-related protein receptor result in selective loss of PTH-stimulated phospholipase C activity
    • (1997) J. Biol. Chem. , vol.272 , pp. 6882-6889
    • Iida-Klein, A.1    Guo, J.2    Takemura, M.3
  • 57
    • 0025675412 scopus 로고
    • Chimeric m2/m3 muscarinic receptors: role of carboxyl terminal receptor domains in selectivity of ligand binding and coupling to phosphoinositide hydrolysis
    • (1990) Mol. Pharmacol. , vol.38 , pp. 872-877
    • Wess, J.1    Bonner, T.I.2    Brann, M.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.