Constitutively active mutants of the β1-adrenergic receptor

FEBS Letters

Volumn 457, Issue 3, 1999, Pages 302-306

  Lattion, Anne Laure ^a   Abuin, Liliane ^a   Nenniger Tosato, Monique ^a   Cotecchia, Susanna ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

Adrenergic receptor; Constitutive activity; G protein coupled receptor; Inverse agonism

Indexed keywords

ALPRENOLOL; ATENOLOL; BETA 1 ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BETAXOLOL; CARVEDILOL; ISOPRENALINE; METOPROLOL; PRACTOLOL; PROPRANOLOL; SOTALOL; TIMOLOL;

AGONIST; ARTICLE; CONTROLLED STUDY; LIGAND BINDING; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL;

ADRENERGIC BETA-AGONISTS; ADRENERGIC BETA-ANTAGONISTS; AMINO ACID SUBSTITUTION; BETAXOLOL; CARBAZOLES; CELL LINE; CYCLIC AMP; EPINEPHRINE; HUMANS; IMIDAZOLES; ISOPROTERENOL; LABETALOL; POINT MUTATION; PRACTOLOL; PROPANOLAMINES; RECEPTORS, ADRENERGIC, BETA-1; RECEPTORS, ADRENERGIC, BETA-2; RECOMBINANT PROTEINS; TIMOLOL;

EID: 0032879444     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(99)01064-9     Document Type: Article

References (16)

1. Wess J. FASEB J. 5:1997;346-354.
2. Kjelsberg M.A., Cotecchia S., Ostrowski J., Caron M.G., Lefkowitz R.J. J. Biol. Chem. 267:1992;1430-1433.
3. Samama P., Cotecchia S., Costa T., Lefkowitz R.J. J. Biol. Chem. 268:1993;4625-4636.
4. Ren, Q., Kurose, H., Lefkowitz, R.J. and Cotecchia, S. (1993) J. Biol. Chem. 268, 16483-16487. [Published erratum in J. Biol. Chem. 269 (1994) 1566].
5. Ren, Q., Kurose, H., Lefkowitz, R.J. and Cotecchia, S. (1993) J. Biol. Chem. 268, 16483-16487. [Published erratum in J. Biol. Chem. 269 (1994) 1566].
6. Scheer A., Cotecchia S. J. Recept. Signal Transduct. Res. 17:1997;57-73.
7. Milligan G., Bond R.A., Lee M. Trends Pharmacol. Sci. 16:1995;10-13.
8. Chidiac P., Hebert T.E., Valiquette M., Dennis M., Bouvier M. Mol. Pharmacol. 45:1994;490-499.
9. Samama P., Pei G., Costa T., Cotecchia S., Lefkowitz R.J. Mol. Pharmacol. 45:1994;390-394.
10. Frielle T., Collins S., Daniel K.W., Caron M.G., Lefkowitz R.J., Kobilka B.K. Pro. Natl. Acad. Sci. USA. 84:1987;7920-7924.
11. Levy F.O., Zhu X., Kaumann A.J., Birnbaumer L. Proc. Natl. Acad. Sci. USA. 90:1993;10798-10802.
12. Green S.A., Holt B.D., Liggett S.B. Mol. Pharmacol. 41:1992;889-893.
13. Bond R.A., Leff P., Johnson T.D., Milano C.A., Rockman H.A., McMinn T.R., Apparsundaram S., Hyek M.F., Kenakin T.P., Allen L.F., Lefkowitz R.J. Nature. 374:1995;272-276.
14. MacEwan D.J., Milligan G. Mol. Pharmacol. 50:1996;1479-1486.
15. Chidiac P., Nouet S., Bouvier M. Mol. Pharmacol. 50:1996;662-669.
16. Mewes T., Dutz S., Ravens U., Jakobs K.H. Circulation. 88:1993;2916-2922.