-
1
-
-
0028094725
-
Internalization of the gastrin-releasing peptide receptor is mediated by both phospholipase C-dependent and -independent processes
-
Benya R. V., Akeson M., Mrozinski J., Jensen R., and Battey J. F. (1994) Internalization of the gastrin-releasing peptide receptor is mediated by both phospholipase C-dependent and -independent processes. Mol. Pharmacol. 46, 495-501.
-
(1994)
Mol. Pharmacol.
, vol.46
, pp. 495-501
-
-
Benya, R.V.1
Akeson, M.2
Mrozinski, J.3
Jensen, R.4
Battey, J.F.5
-
2
-
-
0029016732
-
Residue 78 in the second transmembrane domain of the neurokinin-1 receptor is important in coupling high affinity agonist binding to multiple second messenger responses
-
Brodbeck R. M., Sachais B. S., and Krause J. E. (1995) Residue 78 in the second transmembrane domain of the neurokinin-1 receptor is important in coupling high affinity agonist binding to multiple second messenger responses. Mol. Pharmacol. 47, 1065-1071.
-
(1995)
Mol. Pharmacol.
, vol.47
, pp. 1065-1071
-
-
Brodbeck, R.M.1
Sachais, B.S.2
Krause, J.E.3
-
3
-
-
0028814543
-
Structure-function of muscarinic receptor coupling to G proteins: Random saturation mutagenesis identifies a critical determinant of receptor affinity for G proteins
-
Burstein E. S., Spalding T. A., Hill-Eubanks D., and Brann M. R. (1995) Structure-function of muscarinic receptor coupling to G proteins: random saturation mutagenesis identifies a critical determinant of receptor affinity for G proteins. J. Biol. Chem. 270, 3141-3146.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 3141-3146
-
-
Burstein, E.S.1
Spalding, T.A.2
Hill-Eubanks, D.3
Brann, M.R.4
-
4
-
-
0027202213
-
Molecular cloning and functional expression of a μ opioid receptor from rat brain
-
Chen Y., Mestek A., Liu J., Hurley J. A., and Yu L. (1993) Molecular cloning and functional expression of a μ opioid receptor from rat brain. Mol. Pharmacol. 44, 8-12.
-
(1993)
Mol. Pharmacol.
, vol.44
, pp. 8-12
-
-
Chen, Y.1
Mestek, A.2
Liu, J.3
Hurley, J.A.4
Yu, L.5
-
5
-
-
0001659545
-
Opioid receptor-coupled second messenger system
-
(Hertz A., ed), Springer-Verlag, New York
-
Childers S. R. (1993) Opioid receptor-coupled second messenger system, in Handbook of Experimental Pharmacology, Vol. 104, Pt. 1: Opioids I (Hertz A., ed), pp. 189-216. Springer-Verlag, New York.
-
(1993)
Handbook of Experimental Pharmacology, Vol. 104, Pt. 1: Opioids I
, vol.104
, pp. 189-216
-
-
Childers, S.R.1
-
6
-
-
0025212680
-
1-adrenergic receptor involved in coupling to phosphatidylinositol hydrolysis and enhanced sensitivity of biological functions
-
1-adrenergic receptor involved in coupling to phosphatidylinositol hydrolysis and enhanced sensitivity of biological functions. Proc. Natl. Acad. Sci. USA 87, 2896-2900.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 2896-2900
-
-
Cotecchia, S.1
Exum, S.2
Caron, M.G.3
Lefkowitz, R.J.4
-
8
-
-
0031050888
-
Functional and structural complexity of signal transduction via G-protein-coupled receptors
-
Gudermann T., Schoneberg T., and Schultz G. (1997) Functional and structural complexity of signal transduction via G-protein-coupled receptors. Annu. Rev. Neurosci. 20, 399-427.
-
(1997)
Annu. Rev. Neurosci.
, vol.20
, pp. 399-427
-
-
Gudermann, T.1
Schoneberg, T.2
Schultz, G.3
-
9
-
-
0031776122
-
Effects of C-terminal truncation of the recombinant δ-opioid receptor on phospholipase C and adenylyl cyclase coupling
-
Hirst R. A., Smart D., Devi L. A., and Lambert D. G. (1998) Effects of C-terminal truncation of the recombinant δ-opioid receptor on phospholipase C and adenylyl cyclase coupling. J. Neurochem. 70, 2273-2278.
-
(1998)
J. Neurochem.
, vol.70
, pp. 2273-2278
-
-
Hirst, R.A.1
Smart, D.2
Devi, L.A.3
Lambert, D.G.4
-
10
-
-
0025914068
-
A general method for introducing a series of mutations into cloned DNA using the polymerase chain reaction
-
Ito W., Ishiguro H., and Kurosawa Y. (1991) A general method for introducing a series of mutations into cloned DNA using the polymerase chain reaction. Gene 102, 67-70.
-
(1991)
Gene
, vol.102
, pp. 67-70
-
-
Ito, W.1
Ishiguro, H.2
Kurosawa, Y.3
-
12
-
-
0030736086
-
μ and δ receptors are differentially desensitized by the coexpression of β-adrenergic receptor kinase 2 and β-arrestin 2 in Xenopus oocytes
-
Kovoor A., Nappey V., Kieffer B. L., and Chavkin C. (1997) μ and δ receptors are differentially desensitized by the coexpression of β-adrenergic receptor kinase 2 and β-arrestin 2 in Xenopus oocytes. J. Biol. Chem. 272, 27605-27611.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 27605-27611
-
-
Kovoor, A.1
Nappey, V.2
Kieffer, B.L.3
Chavkin, C.4
-
13
-
-
0027328071
-
Charged amino acids required for signal transduction by the m3 muscarinic acetylcholine receptor
-
Kunkel M. T. and Peralta E. G. (1993) Charged amino acids required for signal transduction by the m3 muscarinic acetylcholine receptor. EMBO J. 12, 3809-3815.
-
(1993)
EMBO J.
, vol.12
, pp. 3809-3815
-
-
Kunkel, M.T.1
Peralta, E.G.2
-
14
-
-
0025600997
-
Distinct sequence elements control the specificity of G protein by muscarinic acetylcholine receptor subtypes
-
Lechleiter J., Hellmiss R., Duerson K., Ennulat D., David N., Clapham D., and Peralta E. (1990) Distinct sequence elements control the specificity of G protein by muscarinic acetylcholine receptor subtypes. EMBO J. 9, 4381-4390.
-
(1990)
EMBO J.
, vol.9
, pp. 4381-4390
-
-
Lechleiter, J.1
Hellmiss, R.2
Duerson, K.3
Ennulat, D.4
David, N.5
Clapham, D.6
Peralta, E.7
-
15
-
-
0029953103
-
Alanine scanning mutagenesis of conserved arginine/lysine-arginine/lysine-X-X-arginine/lysine G protein-activating motifs on ml muscarinic acetylcholine receptors
-
Lee N. H., Geoghagen N. S. M., Cheng E., Cline R. T., and Fraser C. M. (1996) Alanine scanning mutagenesis of conserved arginine/lysine-arginine/lysine-X-X-arginine/lysine G protein-activating motifs on ml muscarinic acetylcholine receptors. Mol. Pharmacol. 50, 140-148.
-
(1996)
Mol. Pharmacol.
, vol.50
, pp. 140-148
-
-
Lee, N.H.1
Geoghagen, N.S.M.2
Cheng, E.3
Cline, R.T.4
Fraser, C.M.5
-
18
-
-
0029991991
-
Different single receptor domains determine the distinct protein coupling profiles of members of vasopressin receptor family
-
Liu J. and Wess J. (1996) Different single receptor domains determine the distinct protein coupling profiles of members of vasopressin receptor family. J. Biol. Chem. 271, 8772-8778.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 8772-8778
-
-
Liu, J.1
Wess, J.2
-
19
-
-
0029589916
-
Identification of a receptor/G-protein contact site critical for signaling specificity and G-protein activation
-
Liu J., Conklin B. R., Blin N., Yun J., and Wess J. (1995) Identification of a receptor/G-protein contact site critical for signaling specificity and G-protein activation. Proc. Natl. Acacl. Sci. USA 92, 11642-11646.
-
(1995)
Proc. Natl. Acacl. Sci. USA
, vol.92
, pp. 11642-11646
-
-
Liu, J.1
Conklin, B.R.2
Blin, N.3
Yun, J.4
Wess, J.5
-
20
-
-
0025332173
-
Molecular characterizations of opioid receptors
-
Loh H. H. and Smith A. P. (1990) Molecular characterizations of opioid receptors. Annu. Rev. Pharmacol. Toxicol. 30, 123-147.
-
(1990)
Annu. Rev. Pharmacol. Toxicol.
, vol.30
, pp. 123-147
-
-
Loh, H.H.1
Smith, A.P.2
-
21
-
-
0025045754
-
Internalization of the Hm1 muscarinic cholinergic receptor involves the third cytoplasmic loop
-
Maeda S., Lameh J., Mallet W. G., Philip M., Ramachandran J., and Sadee W. (1990) Internalization of the Hm1 muscarinic cholinergic receptor involves the third cytoplasmic loop. FEBS Lett. 269, 386-388.
-
(1990)
FEBS Lett.
, vol.269
, pp. 386-388
-
-
Maeda, S.1
Lameh, J.2
Mallet, W.G.3
Philip, M.4
Ramachandran, J.5
Sadee, W.6
-
22
-
-
0028887626
-
Opioid-receptor mRNA expression in the rat CNS: Anatomical and functional implications
-
Mansour A., Fox A. C., Akil H., and Waston S. J. (1995) Opioid-receptor mRNA expression in the rat CNS: anatomical and functional implications. Trends Neurosci. 18, 22-29.
-
(1995)
Trends Neurosci.
, vol.18
, pp. 22-29
-
-
Mansour, A.1
Fox, A.C.2
Akil, H.3
Waston, S.J.4
-
23
-
-
0028180039
-
i protein by peptide structures of the muscarinic M2 receptor second intracellular loop
-
i protein by peptide structures of the muscarinic M2 receptor second intracellular loop. Eur. J. Pharmacol. 267, 185-193.
-
(1994)
Eur. J. Pharmacol.
, vol.267
, pp. 185-193
-
-
McClure, S.J.1
Baron, B.M.2
Harris, B.A.3
-
24
-
-
0029955446
-
Identification of the critical domains of the δ-opioid receptor involved in G protein coupling using site-specific synthetic peptides
-
Merkouris M., Dragatsis I., Meraritis G., Konidakis G., Zioudrou C., Milligan G., and Georgoussi Z. (1996) Identification of the critical domains of the δ-opioid receptor involved in G protein coupling using site-specific synthetic peptides. Mol. Pharmacol. 50, 985-993.
-
(1996)
Mol. Pharmacol.
, vol.50
, pp. 985-993
-
-
Merkouris, M.1
Dragatsis, I.2
Meraritis, G.3
Konidakis, G.4
Zioudrou, C.5
Milligan, G.6
Georgoussi, Z.7
-
25
-
-
0027258001
-
Alternative splicing of C-terminal tail of prostaglandin E receptor subtype EP3 determines G-protein specificity
-
Namba E., Sugimoto Y., Negishi M., Irie A., Ushikubi F., Kakizuka A., Ito S., Ichikawa A., and Narumiya S. (1993) Alternative splicing of C-terminal tail of prostaglandin E receptor subtype EP3 determines G-protein specificity. Nature 365, 166-170.
-
(1993)
Nature
, vol.365
, pp. 166-170
-
-
Namba, E.1
Sugimoto, Y.2
Negishi, M.3
Irie, A.4
Ushikubi, F.5
Kakizuka, A.6
Ito, S.7
Ichikawa, A.8
Narumiya, S.9
-
26
-
-
0000751786
-
Opioid actions on membrane ion channels
-
(Hertz A., ed), Springer-Verlag, New York
-
North R. A. (1993) Opioid actions on membrane ion channels, in Handbook of Experimental Pharmacology, Vol. 104, Pt. 1: Opioids I (Hertz A., ed), pp. 773-797. Springer-Verlag, New York.
-
(1993)
Handbook of Experimental Pharmacology, Vol. 104, Pt. 1: Opioids I
, vol.104
, pp. 773-797
-
-
North, R.A.1
-
27
-
-
0026630552
-
2-adrenergic receptors based upon characteristics in primary structure
-
2-adrenergic receptors based upon characteristics in primary structure. J. Biol. Chem. 267, 8342-8346.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 8342-8346
-
-
Okamoto, T.1
Nishimoto, I.2
-
29
-
-
0030875721
-
Agonist-induced desensitization of the μ opioid receptor is determined by threonine 394 preceded by acidic amino acids of the COOH-terminal tail
-
Pak J. S., O'Dowd B. F., and George S. (1997) Agonist-induced desensitization of the μ opioid receptor is determined by threonine 394 preceded by acidic amino acids of the COOH-terminal tail. J. Biol. Chem. 272, 24961-24965.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 24961-24965
-
-
Pak, J.S.1
O'Dowd, B.F.2
George, S.3
-
30
-
-
0000625397
-
Molecular biology of the opiate receptors
-
Reisine T. and Bell G. I. (1993) Molecular biology of the opiate receptors. Trends Neurosci. 16, 384-389.
-
(1993)
Trends Neurosci.
, vol.16
, pp. 384-389
-
-
Reisine, T.1
Bell, G.I.2
-
32
-
-
0026548156
-
In vitro mutagenesis and the search for structure-function relationships among G protein-coupled receptors
-
Savarese T. M. and Fraser C. M. (1992) In vitro mutagenesis and the search for structure-function relationships among G protein-coupled receptors. Biochem. J. 283, 1-19.
-
(1992)
Biochem. J.
, vol.283
, pp. 1-19
-
-
Savarese, T.M.1
Fraser, C.M.2
-
33
-
-
0028289513
-
Structure and function of G protein-coupled receptors
-
Strader C. D., Fong T. M., Michael R. T., Underwood D., and Dixon R. A. F. (1994) Structure and function of G protein-coupled receptors. Annu. Rev. Biochem. 63, 101-132.
-
(1994)
Annu. Rev. Biochem.
, vol.63
, pp. 101-132
-
-
Strader, C.D.1
Fong, T.M.2
Michael, R.T.3
Underwood, D.4
Dixon, R.A.F.5
-
34
-
-
0026787417
-
G protein-bound conformation of mastoparan-X, a receptor-mimetic peptide
-
Sukumar M. and Higashijima T. (1992) G protein-bound conformation of mastoparan-X, a receptor-mimetic peptide. J. Biol. Chem. 267, 21421-21424.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 21421-21424
-
-
Sukumar, M.1
Higashijima, T.2
-
35
-
-
0027504836
-
Cloning and pharmacological characterization of a rat μ opioid receptor
-
Thompson R. C., Mansour A., Akil H., and Watson S. J. (1993) Cloning and pharmacological characterization of a rat μ opioid receptor. Neuron 11, 903-913.
-
(1993)
Neuron
, vol.11
, pp. 903-913
-
-
Thompson, R.C.1
Mansour, A.2
Akil, H.3
Watson, S.J.4
-
36
-
-
0029825797
-
Sequestration of the δ opioid receptor: Role of the C-terminus in agonist-mediated internalization
-
Trapaidze N., Keith D. E., Cvejic S., Evans C. J., and Devi L. A. (1996) Sequestration of the δ opioid receptor: role of the C-terminus in agonist-mediated internalization. J. Biol. Chem. 271, 29279-29285.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 29279-29285
-
-
Trapaidze, N.1
Keith, D.E.2
Cvejic, S.3
Evans, C.J.4
Devi, L.A.5
-
39
-
-
0030943262
-
Basic amino acids at the C-terminus of the third intracellular loop are required for the activation of phospholipase C by cholecystokinin-B receptors
-
Wang H.-L. (1997) Basic amino acids at the C-terminus of the third intracellular loop are required for the activation of phospholipase C by cholecystokinin-B receptors. J. Neurochem. 68, 1728-1735.
-
(1997)
J. Neurochem.
, vol.68
, pp. 1728-1735
-
-
Wang, H.-L.1
-
40
-
-
0028089275
-
Human μ opiate receptor: CDNA and genomic clones, pharmacologic characterization and chromosomal assignment
-
Wang J. B., Johnson P. S., Persico A. M., Hawkins A. L., Griffin C. A., and Uhl G. R. (1994) Human μ opiate receptor: cDNA and genomic clones, pharmacologic characterization and chromosomal assignment. FEBS Lett. 338, 217-222.
-
(1994)
FEBS Lett.
, vol.338
, pp. 217-222
-
-
Wang, J.B.1
Johnson, P.S.2
Persico, A.M.3
Hawkins, A.L.4
Griffin, C.A.5
Uhl, G.R.6
-
42
-
-
0029949928
-
Opioid receptor types and subtypes: The δ receptor as a model
-
Zaki P. A., Bilsky E. J., Vanerah T. W., Lai J., Evans C. J., and Porreca F. (1996) Opioid receptor types and subtypes: the δ receptor as a model. Annu. Rev. Pharmacol. Toxicol. 36, 379-401.
-
(1996)
Annu. Rev. Pharmacol. Toxicol.
, vol.36
, pp. 379-401
-
-
Zaki, P.A.1
Bilsky, E.J.2
Vanerah, T.W.3
Lai, J.4
Evans, C.J.5
Porreca, F.6
|