Enhancement of membrane-type 1-matrix metalloproteinase (MT1-MMP) production and sequential activation of progelatinase A on human squamous carcinoma cells co-cultured with human dermal fibroblasts

British Journal of Cancer

Volumn 80, Issue 8, 1999, Pages 1137-1143

  Sato, T ^a   Iwai, M ^a   Sakai, T ^a   Sato, H ^b   Seiki, M ^c   Mori, Y ^a   Ito, A ^a  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

^b KANAZAWA UNIVERSITY   (Japan)

^c THE UNIVERSITY OF TOKYO   (Japan)

Author keywords

Co culture; Human dermal fibroblasts; Human squamous carcinoma cells; Membrane type 1 matrix metalloproteinase; Progelatinase A

Indexed keywords

ENZYME PRECURSOR; EPIDERMAL GROWTH FACTOR; GELATINASE A; MATRIX METALLOPROTEINASE; MESSENGER RNA;

ARTICLE; CANCER CELL CULTURE; CELL INTERACTION; CELL INVASION; COCULTURE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INDUCTION; ENZYME SYNTHESIS; FIBROBLAST; GENE INDUCTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA;

EID: 0033019758     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6690477     Document Type: Article

References (40)

1. Azzam H, Arand G, Lippman ME and Thompson EW (1993) Association of MMP-2 activation potential with metastatic progression in human breast cancer cell lines independent of MMP-2 production. J Natl Cancer Inst 85: 1758-1764
2. Baramova EN, Bajou K, Remacle A, L'Hoir C, Krell HW, Weidle UH, Noel A and Foidart JM (1997) Involvement of PA/plasmin system in the processing of proMMP-9 and in the second step of pro-MMP-2 activation. FEBS Lett 405: 157-162
3. Birkedal-Hansen H, Moore WGI, Bodden MK, Windsor LJ, Birkedal-Hansen B, DeCarlo A and Engler JA (1993) Matrix metalloproteinases: a review. Crit Rev Oral Biol Med 4: 197-250
4. Bronner-Fraser M (1985) Alterations in neural crest migration by a monoclonal antibody that affects cell adhesion. J Cell Biol 101: 610-617
5. Ito A and Nagase H (1988) Evidence that human rheumatoid synovial matrix metalloproteinase 3 is an endogenous activator of procollagenase. Arch Biochem Biophys 267: 211-2216
6. Ito A, Itoh Y, Sato T, Mori Y, Suzuki K and Nagase H (1991) Identification of rabbit uterine cervical procollagenase activator as rabbit matrix metalloproteinase 3 (stromelysin). Comp Biochem Physiol 99B: 381-385
7. Ito A, Nakajima S, Sasaguri Y, Nagase H and Mori Y (1995) Co-culture of human breast adenocarcinoma MCF-7 cells and human dermal fibroblasts enhances the production of matrix metalloproteinases 1, 2 and 3 in fibroblasts. Br J Cancer 71: 1039-1045
8. Ito A, Yamada M, Sato T, Sanekata K, Sato H, Seiki M, Nagase H and Mori Y (1998) Calmodulin antagonists increase the expression of membrane-type-I matrix metalloproteinase in human uterine cervical fibroblasts. Eur J Biochem 251: 353-358
9. Itoh Y, Binner S and Nagase H (1995) Steps involved in activation of the complex of promatrix metalloproteinase 2 (progelatinase A) and tissue inhibitor of metalloproteinases (TIMP)-2 by 4-aminophenylmercuric acetate. Biochem J 308: 645-651
10. Kinoshita T, Sato H, Takino T, Itoh M, Akizawa T and Seiki M (1996) Processing of a precursor of 72 kilodalton type IV collagenase/gelatinase A by a recombinant membrane-type 1 matrix metalloproteinase. Cancer Res 56: 2535-2538
11. Kinoshita T, Sato H, Okada A, Ohuchi E, Imai K, Okada Y and Seiki M (1998) TIMP-2 promotes activation of progelatinase A by membrane-type 1 matrix metalloproteinase immobilized on agarose beads. J Biol Chem 273: 16098-16103
12. Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (London) 227: 680-685
13. Lohi J and Keski-Oja J (1995) Calcium ionophores decrease pericellular gelatinolytic activity via inhibition of 92-kDa gelatinase expression and decrease of 72-kDa gelatinase activation. J Biol Chem 270: 17602-17609
14. Lohi J, Lehti K, Westermarck J, Kähäri V-M and Keski-Oja J (1996) Regulation of membrane-type matrix metalloproteinase-1 expression by growth factors and phorbol 12-myristate 13-acetate. Eur J Biochem 239: 239-247
15. Lowry OH, Rosebrough NJ, Lewis Farr A and Randall RJ (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 193: 265-275
16. Mazzieri R, Masiero L, Zanetta L, Monea S, Onisto M, Garbisa S and Mignatti P (1997) Control of type IV collagenase activity by components of the urokinase-plasmin system: a regulatory mechanism with cell-bound reactants. EMBO J 16: 2319-2332
17. Ogata Y, Enghild JJ and Nagase H (1992) Matrix metalloproteinase 3 (stromelysin) activates the precursor for the human matrix metalloproteinase 9. J Biol Chem 267: 3581-3584
18. Okada Y, Morodomi T, Enghild JJ, Suzuki K, Yasui A, Nakanishi I, Salvesen G and Nagase H (1990) Matrix metalloproteinase 2 from human rheumatoid synovial fibroblasts. Purification and activation of the precursor and enzymic properties. Eur J Biochem 194: 721-730
19. Ozawa S, Ueda M, Ando N. Abe O and Shimizu N (1987) High incidence of EGF receptor hyperproduction in esophapeal squamous cell carcinomas. Int J Cancer 39: 333-337
20. Pei D and Weiss SJ (1996) Transmembrane-deletion mutants of the membrane-type matrix metalloproteinase-1 process progelatinase A and express intrinsic matrix-degrading activity. J Biol Chem 271: 9135-9140
21. Polette M, Gilles C, Marchard V, Seiki M, Tournier J-M and Birembaut P (1997) Induction of membrane-type matrix metalloproteinase 1 (MTI-MMP) expression in human fibroblasts by breast adenocarcinoma cells. Clin Exp Metastasis 15: 157-163
22. Puente XS, Pendás AM, Llano E, Velasco G and López-Otín C (1996) Molecular cloning of a novel membrane-type matrix metalloproteinase from a human breast carcinoma. Cancer Res 56: 944-949
23. Pyke C, Ralfkiær E, Huhtala P, Hurskainen T, Danø K and Tryggvason K (1992) Localization of messenger RNA for Mr 72 000 and 92 000 type IV collagenase in human skin cancers by in situ hybridization. Cancer Res 52: 1336-1341
24. Sato H, Takino T, Okada Y, Cao J, Shinagawa A, Yamamoto E and Seiki M (1994) A matrix metalloproteinase expressed on the surface of invasive tumor cells. Nature 370: 61-65
25. Sato T, Kirimura Y and Mori Y (1997) The co-culture of dermal fibroblasts with human epidermal keratinocytes induces increased prostaglandin E, production and cyclooxygenase 2 activity in fibroblasts. J Invest Dermatol 109: 334-339
26. Seltzer JL, Lee A-Y, Akers KT, Sudheck B, Southon EA, Wayner EA and Eisen AZ (1994) Activation of 72 kDa type IV collagenase/gelatinase by normal fibroblasts in collagen lattices is mediated by integrin receptors but is not related to lattice contraction. Exp Cell Res 213: 365-374
27. Shima I, Sasaguri Y, Kusukawa J, Nakano R, Yamana H, Fujita H, Kakegawa T and Morimatsu M (1993) Production of matrix metalloproteinase 9 (92 kDa gelatinase) by human oesophageal squamous cell carcinoma in response to epidermal growth factor. Br J Cancer 67: 721-727
28. Singletary SE, Baker FL, Spitzer G, Tucker SL, Tomasovic B, Brock WA, Ajani JA and Kelly AM (1987) Biological effect of epidermal growth factor on the in vitro growth of human tumors. Cancer Res 47: 403-406
29. Stearns ME and Wang M (1993) Type IV collagenase (Mr 72 000) expression in human prostate: benign and malignant tissue. Cancer Res 53: 878-883
30. Stetler-Stevenson WG, Aznavoorian S and Liotta LA (1993) Tumor cell interactions with the extracellular matrix during invasion and metastasis. Annu Rev Cell Biol 9: 541-573
31. Strongin AY, Marmer BL, Grant GA and Goldberg GI (1993) Plasma membrane-dependent activation of the 72-kDa type IV collagenase is prevented by complex formation with TIMP-2. J Biol Chem 268: 14033-14039
32. Strongin AY, Collier I, Bannikov G, Manner BL, Grant GA und Goldberg GI (1995) Mechanism of cell surface activation of 72-kDa typc IV collagenase: isolation of the activated form of the membrane metalloproteinase. J Biol Chem 270: 5331-5338
33. Takahashi S, Ito A, Nagino M, Mori Y, Xie B and Nagase H (1991) Cyclic adenosine 3′, 5′-monophosphate suppresses interleukin 1-induced synthesis of matrix metalloproteinases but not of tissue inhibitor of metalloproteinases in human uterine cervical fibroblasts. J Biol Chem 266: 19894-19899
34. Takino T, Sato H, Shinagawa A and Seiki M (1995) Identification of the second membrane-type matrix metalloproteinase (MT-MMP-2) gene from a human placenta cDNA library: MT-MMPs from a unique membrane-type subclass in the MMP family. J Biol Chem 270: 23013-23020
35. Ueno H, Nakamura M, Inoue M, Imai K, Noguchi M, Sato H, Seiki M and Okada Y (1997) Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in human invasive breast carcinomas. Cancer Res 57: 2055-2060
36. Ward RV, Atkinson SJ, Slocombe PM, Docherty AJP, Reynolds JJ and Murphy G (1991) Tissue inhibitor of metalloproteinases-2 inhibits the activation of 72 kDa progelatinase by fibroblast membranes. Biochim Biophys Acta 1079: 242-246
37. Westerlund A, Hujanen E, Puistola U and Turpeenniemi-Hujanen T (1997) Fibroblasts stimulate human ovarian cancer cell invasion and expression of 72-kDa gelatinase A (MMP-2). Gynecol Oncol 67: 76-82
38. Will H and Hinzmann B (1995) cDNA sequence and mRNA distribution of a novel human matrix metalloproteinase with a potential transmembrane domain. Eur J Biochem 231: 602-608
39. Will H, Atkinson SJ, Butler GS, Smith B and Murphy G (1996) The soluble catalytic domain of membrane type 1 matrix metalloproteinase cleaves the propeptide of progelatinase A and initiates autoproteolytic activation: regulation by TIMP-2 and TIMP 3. J Biol Chem 271: 17119-17123
40. Yamamoto M, Mohanam S, Sawaya R, Fuller GN, Seiki M, Sato H, Gokaslan ZL, Liotta LA, Nicolson GL and Rao JS (1996) Differential expression of membrane-type matrix metalloproteinase and its correlation with gelatinase A activation in human malignant brain tumors in vitro and in vivo. Cancer Res 56: 384-392