Role of tissue inhibitor of metalloproteinases-2 (TIMP-2) in regulation of pro-gelatinase A activation catalyzed by membrane-type matrix metalloproteinase-1 (MT1-MMP) in human cancer cells

Journal of Biochemistry

Volumn 124, Issue 2, 1998, Pages 462-470

  Shofuda, Ken Ichi ^a,b   Moriyama, Kayano ^a   Nishihashi, Ai ^a   Higashi, Shouichi ^a   Mizushima, Hiroto ^a   Yasumitsu, Hidetaro ^a   Miki, Keizaburo ^b   Sato, Hiroshi ^c   Seiki, Motoharu ^c,d   Miyazaki, Kaoru ^a  

^a YOKOHAMA CITY UNIVERSITY   (Japan)

^b Terumo R and D Center   (Japan)

^c KANAZAWA UNIVERSITY   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

Author keywords

Concanavalin A; Gelatinase A (MMP 2); Membrane type matrix metalloproteinase 1 (MT1 MMP); Phorbor ester (TPA); Tissue inhibitor of metalloproteinase 2 (TIMP 2)

Indexed keywords

CONCANAVALIN A; ENZYME PRECURSOR; GELATINASE A; MEMBRANE METALLOENDOPEPTIDASE; MESSENGER RNA; METALLOPROTEINASE; PHORBOL ESTER; TISSUE INHIBITOR OF METALLOPROTEINASE;

ARTICLE; CANCER CELL CULTURE; CATALYSIS; CELL MEMBRANE; COMPLEX FORMATION; CULTURE MEDIUM; ENZYME ACTIVATION; FIBROSARCOMA; HUMAN; HUMAN CELL; SQUAMOUS CELL CARCINOMA;

EID: 0031656621     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a022136     Document Type: Article

References (41)

1. Liotta, L.A. (1986) Tumor invasion and metastases - role of the extracellular matrix: Rhoads memorial award lecture. Cancer Res. 46, 1-7
2. Stetler-Stevenson, W.G., Aznavoorian, S., and Liotta, L.A. (1993) Tumor cell interactions with the extracellular matrix during invasion and metastasis. Annu. Rev. Cell Biol. 9, 541-573
3. Corcoran, M.L., Hewitt, R.E., Kleiner, D.E. Jr., and Stetler-Stevenson, W.G. (1996) MMP-2: Expression, activation and inhibition. Enzyme Protein 49, 7-19
4. Collier, I.E., Wilhelm, S.M., Eisen, A.Z., Marmer, B.L., Grant, G.A., Seltzer, J.L., Kronberger, A., He, C.S., Bauer, E.A., and Goldberg, G.I. (1988) H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloproteinase capable of degrading basement membrane collagen. J. Biol. Chem. 263, 6579-6587
5. Bernhard, E.J., Gruber, S.B., and Muschel, R.J. (1994) Direct evidence linking expression of matrix metalloproteinase 9 (92-kDa gelatinase/collagenase) to the metastatic phenotype in transformed rat embryo cells. Proc. Natl. Acad. Sci. USA 91, 4293-4297
6. Brown, P.D., Bloxidge, R.E., Stuart, N.S., Gatter, K.C., and Carmechael, J. (1993) Association between expression of activated 72-kilodalton gelatinase and tumor spread in non-small-cell lung carcinoma. J. Natl. Cancer Inst. 85, 574-578
7. Azzam, H.S., Arand, G., Lippman, M.E., and Thompson, E.W. (1993) Association of MMP-2 activation potential with metastatic progression in human cancer cell lines independent of MMP-2 production. J. Natl. Cancer Inst. 85, 1758-1764
8. Sato, H., Takino, T., Okada, Y., Cao, J., Shinagawa, A., Yamamoto, E., and Seiki, M. (1994) A matrix metalloproteinase expressed on the surface of invasive tumor cells. Nature 370, 61-65
9. Okada, A., Bellocq, J.P., Rouyer, N., Chenard, M.P., Rio, M.C., Chambon, P., and Basset, P. (1995) Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas. Proc. Natl. Acad. Sci. USA 92, 2730-2734
10. Nomura, H., Sato, H., Seiki, M., Mai, M., and Okada, Y. (1995) Expression of membrane-type matrix metalloproteinase in human gastric carcinomas. Cancer Res. 55, 3263-3266
11. Yamamoto, M., Mohanam, S., Sawaya, R., Fuller, G.N., Seiki, M., Sato, H., Gokaslan, Z.L., Liotta, L.A., Nicolson, G.L., and Rao, J.S. (1996) Differential expression of membrane-type matrix metalloproteinase and its correlation with gelatinase A activation in human malignant brain tumors in vivo and in vitro. Cancer Res. 56, 384-392
12. Will, H. and Hinzmann, B. (1995) cDNA Sequence and mRNA tissue distribution of a novel human matrix metalloproteinase with a potential transmembrane segment. Eur. J. Biochem. 231, 602-608
13. Takino, T., Sato, H., Shinagawa, A., and Seiki, M. (1995) Identification of the second membrane-type matrix metalloproteinase (MT-MMP-2) gene from a human placenta cDNA library. J. Biol. Chem. 270, 23013-23020
14. Puente, X.S., Pendas, A.M., Llano, E., Velasco, G., and Lopez-Otin, C. (1996) Molecular cloning of a novel membrane-type matrix metalloproteinase from a human breast carcinoma. Cancer Res. 56, 944-949
15. Tanaka, M., Sato, H., Takino, T., Iwata, K., Inoue, M., and Seiki, M. (1997) Isolation of a mouse MT2-MMP gene from a lung cDNA library and identification of its product. FEBS Lett. 402, 219-222
16. Shofuda, K., Yasumitsu, H., Nishihashi, A., Miki, K., and Miyazaki, K. (1997) Expression of three membrane-type matrix metalloproteinases (MT-MMPs) in rat vascular smooth muscle cells and characterization of MTS-MMPs with and without transmembrane domain. J. Biol. Chem. 272, 9749-9754
17. Atkinson, S.J., Crabbe, T., Cowell, S., Ward, R.V., Butler, M.J., Sato, H., Seiki, M., Reynolds, J.J., and Murphy, G. (1995) Intermolecular autolytic cleavage can contribute to the activation of progelatinase A by cell membranes. J. Biol. Chem. 270, 30479-30485
18. Will, H., Atkinson, S.J., Butler, O.S., Smith, B., and Murphy, G. (1996) The soluble catalytic domain of membrane type 1 matrix metalloproteinase cleaves the propeptide of progelatinase A and initiates autolytic activation. J. Biol. Chem. 271, 17119-17123
19. Strongin, A.Y., Collier, I., Bannikov, G., Marmer, B.L., Grant G.A., and Goldberg, G.I. (1995) Mechanism of cell surface activation of 72-kDa type IV collagenase. J. Biol. Chem. 270, 5331-5338
20. Yu, M., Sato, H., Seiki, M., and Thompson, E.W. (1996) Complex regulation of membrane-type matrix metalloproteinase expression and matrix metalloproteinase-2 activation by concanavalin A in MDA-MB-231 human breast cancer cells Cancer Res. 55, 3272-3277
21. Lohi, J., Lehti, K., Westermarck, J., Kahari, V.-M., and Keski-Oja, J. (1996) Regulation of membrane-type matrix metalloproteinase-1 expression by growth factors and phorbor 12-myristate 13-acetate. Eur. J. Biochem. 239, 239-247
22. Kawano, N., Osawa, H., Ito, T., Nagashima, Y., Hirahara, F., Inayama, Y., Nakatani, Y., Kimura, S., Kitajima, H., Koshikawa, N., Miyazaki, K., and Kitamura, H. (1997) Expression of gelatinase A, tissue inhibitor of metalloproteinase-2, matrilysin, and trypsin(ogen) in lung neoplasms: An immunohistochemical study. Hum. Pathol. 28, 613-622
23. Sato, H., Kida, Y., Mai, M., Endo, Y., Sasaki, T., Tanaka, J., and Seiki, M. (1992) Expression of genes encoding type IV collagen-degrading metalloproteinases and tissue inhibitors of metalloproteinases in various human tumor cells. Oncogene 7, 77-83
24. Koshikawa, N., Yasumitsu, H., Umeda, M., and Miyazaki, K. (1992) Multiple secretion of matrix serine proteinases by human gastric carcinoma cell lines. Cancer Res. 52, 5046-5053
25. Chomczynski, P. and Sacchi, N. (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162, 156-159
26. Okayama, H. and Berg, P. (1983) A cDNA cloning vector that permits expression of cDNA inserts in mammalian cells. Mol. Cell Biol. 3, 280-289
27. Ward, R.V., Atkinson, S.J., Slocombe, P.M., Docherty, A.J., Reynolds, J.J., and Murphy, G. (1991) Tissue inhibitor of metalloproteinases-2 inhibits the activation of 72 kDa progelatinase by fibroblast membranes. Biochim. Biophys Acta 1079, 242-246
28. Ueno, H., Nakamura, H., Inoue, M., Imai, K., Noguchi, M., Sato, H., Seiki, M., and Okada, Y. (1997) Expression and tissue localization of membrane-type 1, 2, and 3 matrix metalloproteinases in human invasive breast carcinomas. Cancer Res. 57, 2055-2060
29. Sato, H., Kinoshita, T., Takino, T., Nakayama, K., and Seiki, M. (1996) Activation of a recombinant membrane type 1-matrix metalloproteinase (MT1-MMP) by furin and its interaction with tissue inhibitor of metalloproteinases (TIMP)-2. FEBS Lett. 393, 101-104
30. Butler, G.S., Will, H., Atkinson, S.J., and Murphy, G. (1997) Membrane-type-2 matrix metalloproteinase can initiate the processing of progelatinase A and is regulated by the tissue inhibitor of metalloproteinases. Eur. J. Biochem. 244, 653-657.
31. Butler, G.S., Butler, M.J., Atkinson, S.J., Will, H., Tamura, T., van Westrum, S.S., Crabbe, T., Clements, J., d'Ortho, M.P., and Murphy, G. (1998) The TIMP2 membrane type 1 metalloproteinase "receptor" regulates the concentration and efficient activation of progelatinase A - a kinetic study. J. Biol. Chem. 273, 871-880
32. Perlmutter, D.H., Glover, G.I., Rivetna, M., Schasteen, C.S., and Fallon, R.J. (1990) Identification of a serpin-enzyme complex receptor on human hepatoma cells and human monocytes. Proc. Natl. Acad. Sci. USA 87, 3753-3757
33. Boland, K., Behrens, M., Choi, D., Manias, K., and Perlmutter, D.H. (1996) The serpin-enzyme complex receptor recognizes soluble, nontoxic amyloid-β peptide but not aggregated, cytotoxic amyloid-β peptide. J. Biol. Chem. 271, 18032-18044
34. Pei, D. and Weiss, S.J. (1995) Furin-dependent intracellular activation of the human stromelysin-3 zymogen. Nature 375, 244-247.
35. Gervasi, D.C., Raz, A., Dehem, M., Yang, M., Kurkinen, M., and Fridman, R. (1996) Carbohydrate-mediated regulation of matrix metalloproteinase-2 activation in normal human fibroblast and fibrosarcoma cells. Biochem. Biophys. Res. Commun. 228, 530-538
36. Overall, C.M. and Sodek, J. (1990) Concanavalin A produces a matrix-degradative phenotype in human fibroblasts. J. Biol. Chem. 265, 21141-21151
37. Shiba, T., Tobe, K., Koshio, O., Yamamoto, R., Shibasaki, Y., Matsumoto, N., Toyoshima, S., Osawa, T., Akanuma, Y., Takaku, F., and Kasuga, M. (1990) Concanavalin A-induced receptor aggregation stimulates the tyrosine kinase activity of the insulin receptor in intact cells. Biochem. J. 267, 787-794
38. Faltynek, C.R., Princler, G.L., Ruscetti, F.W., and Birchenall-Sparks, M. (1988) Lectins modulate the internalization of recombinant interferon-α and the induction of 2′,5′-oligo(A) synthetase. J. Biol. Chem. 263, 7112-7117
39. Tomasek, J.J., Halliday, N.L., Updike, D.L., Ahern-Moore, J. S., Vu, T.-K., H., Liu, R.W., and Howard, E.W. (1997) Gelatinase A activation is regulated by the organization of the polymerized actin cytoskeleton. J. Biol. Chem. 272, 7482-7487
40. Lee, A.Y., Akers, K.T., Collier, M., Li, L., Eisen, A.Z., and Seltzer, J.L. (1997) Intracellular activation of gelatinase A (72-kDa type IV collagenase) by normal fibroblasts. Proc. Natl. Acad. Sci. USA 94, 4424-4429
41. Zempo, N., Kenagy, R.D., Au, Y.P., Bendeck, M., Clowes, M.M., Reidy, M.A., and Clowes, A.W. (1994) Matrix metalloproteinases of vascular wall cells are increased in balloon-injured rat carotid artery. J. Vasc. Surg. 20, 209-217