Protease activation during apoptosis: Death by a thousand cuts?

Cell

Volumn 82, Issue 3, 1995, Pages 349-352

  Martin, Seamus J ^a   Green, Douglas R ^a  

^a LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEINASE;

ANIMAL CELL; APOPTOSIS; CELL DEATH; DIAGNOSIS; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME SUBSTRATE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; REGULATORY MECHANISM; SHORT SURVEY;

ANIMAL; APOPTOSIS; ENDOPEPTIDASES; HUMAN;

EID: 0029125701     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0092-8674(95)90422-0     Document Type: Short Survey

References (30)

1. CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme.
2. Identification and characterization of ICH-2, a novel member of the interleukin-1 beta-converting enzyme family of cysteine proteases.
3. Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 beta-converting enzyme.
4. Studies of the lamin proteinase reveal multiple parallel biochemical pathways during apoptotic execution.