Pteridine salvage throughout the Leishmania infectious cycle: Implications for antifolate chemotherapy

Molecular and Biochemical Parasitology

Volumn 113, Issue 2, 2001, Pages 199-213

  Cunningham, Mark L ^a   Beverley, Stephen M ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Biopterin transporter; Developmental regulation; Dihydrofolate reductase; Folate transporter; HPLC biopterin assay; Pteridine reductase

Indexed keywords

BIOPTERIN; CARRIER PROTEIN; FOLATE TRANSPORTER; FOLIC ACID ANTAGONIST; OXIDOREDUCTASE; PROTOZOAL RNA; PTERIDINE; PTERIDINE REDUCTASE; UNCLASSIFIED DRUG;

AMASTIGOTE; ANTIBIOTIC THERAPY; ARTICLE; CELL LYSATE; CONTROLLED STUDY; ENZYME ACTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LEISHMANIA; LEISHMANIASIS; MACROPHAGE; NONHUMAN; PRIORITY JOURNAL; RNA TRANSCRIPTION; TRANSCRIPTION REGULATION;

ANIMALS; BIOPTERIN; CARRIER PROTEINS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FOLIC ACID; FOLIC ACID ANTAGONISTS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; LEISHMANIA; LEISHMANIASIS; MEMBRANE TRANSPORT PROTEINS; MOLECULAR SEQUENCE DATA; MULTIENZYME COMPLEXES; OXIDOREDUCTASES; PROTOZOAN PROTEINS; PTERIDINES; RNA, MESSENGER; TETRAHYDROFOLATE DEHYDROGENASE; THYMIDYLATE SYNTHASE;

PROTOZOA; TRYPANOSOMATIDAE;

EID: 0035815312     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(01)00213-4     Document Type: Article

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