Role of the locus and of the resistance gene on gene amplification frequency in methotrexate resistant Leishmania tarentolae

Nucleic Acids Research

Volumn 27, Issue 18, 1999, Pages 3653-3659

  Kündig, Christoph ^b   Leblanc, Éric ^b   Papadopoulou, Barbara ^b   Ouellette, Marc ^a  

^a LAVAL UNIVERSITY   (Canada)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; DIHYDROFOLATE REDUCTASE; FOLIC ACID; METHOTREXATE; PROTOZOAL DNA; PTERIN; THYMIDYLATE SYNTHASE;

ARTICLE; CONTROLLED STUDY; DRUG RESISTANCE; DRUG TRANSPORT; ENZYME ACTIVITY; GENE AMPLIFICATION; GENE FUNCTION; GENE LOCUS; GENE TARGETING; GENETIC TRANSFECTION; ISOTOPE LABELING; LEISHMANIA; NONHUMAN; PRIORITY JOURNAL;

ALLELES; ANIMALS; BIOLOGICAL TRANSPORT; CELL LINE; DNA, PROTOZOAN; DNA, RECOMBINANT; DRUG RESISTANCE; FOLIC ACID ANTAGONISTS; GENE AMPLIFICATION; GENE DOSAGE; GENES, PROTOZOAN; LEISHMANIA; METHOTREXATE; MULTIENZYME COMPLEXES; MUTATION; OXIDOREDUCTASES; PHENOTYPE; REPETITIVE SEQUENCES, NUCLEIC ACID; SELECTION (GENETICS); TETRAHYDROFOLATE DEHYDROGENASE; THYMIDYLATE SYNTHASE; TRANSFECTION;

EID: 0345061684     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/27.18.3653     Document Type: Article

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