Nuclear interpretation of Dpp signaling in Drosophila

EMBO Journal

Volumn 20, Issue 13, 2001, Pages 3298-3305

  Affolter, M ^a   Marty, T ^a   Vigano, M A ^a   Jazwinska A ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

Author keywords

Dpp; Morphogen gradient; Nuclear signaling; Selector proteins; TGF

Indexed keywords

DECAPENTAPLEGIC PROTEIN; NUCLEAR PROTEIN; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

DROSOPHILA MELANOGASTER; MORPHOGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; BODY PATTERNING; CELL NUCLEUS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; EMBRYO, NONMAMMALIAN; INSECT PROTEINS; MODELS, BIOLOGICAL; MORPHOGENESIS; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA;

EID: 0035796557     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.13.3298     Document Type: Review

References (52)

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4. Restricted patterning of vestigial expression in Drosophila wing imaginal discs requires synergistic activation by both mad and the drifter POU domain transcription factor
5. A transcriptional partner for MAD proteins in TGFβ signalling
6. Determinants of specificity in TGFβ signal transduction
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10. A DNA-binding protein containing two widely separated zinc finger motifs that recognize the same DNA sequence
11. Schnurri is required for Drosophila Dpp signaling and encodes a zinc finger protein similar to the mammalian transcription factor PRDIIBF1
12. Synergistic activation of a Drosophila enhancer by HOM/EXD and DPP signaling
13. Biochemical and biophysical characterization of refolded Drosophila DPP, a homolog of bone morphogenetic proteins 2 and 4
14. The Vestigial and Scalloped proteins act together to directly regulate wing-specific gene expression in Drosophila
15. Ras pathway specificity is determined by the integration of multiple signal-activated and tissue-restricted transcription factors
16. The Drosophila gene brinker reveals a novel mechanism of Dpp target gene regulation
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27. The repressor and activator forms of cubitus interruptus control hedgehog target genes through common generic gli-binding sites
28. Direct and long-range action of a DPP morphogen gradient
29. Spatially restricted activation of the SAX receptor by SCW modulates DPP/TKV signaling in Drosophila dorsal-ventral patterning
30. Interpretation of a BMP activity gradient in Drosophila embryos depends on synergistic signaling by two type I receptors, SAX and TKV
31. Interaction between Wnt and TGFβ signalling pathways during formation of Spemann's organizer
32. Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster. I. Zygotic loci on the second chromosome
33. Drosophila segment borders result from unilateral repression of hedgehog activity by wingless signaling
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38. Regulation of Hox target genes by a DNA bound Homothorax/Hox/Extradenticle complex
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40. Genetic characterization and cloning of mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster
41. Structural insights on Smad function in TGFβ signaling
42. Direct transcriptional control of the dpp target omb by the DNA binding protein brinker
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44. A Drosophila protein related to the human zinc finger transcription factor PRDII/MBPI/HIV-EP1 is required for dpp signaling
45. Functional intertwining of Dpp and EGFR signaling during Drosophila endoderm induction
46. Hedgehog creates a gradient of DPP activity in Drosophila wing imaginal discs
47. Dpp gradient formation in the Drosophila wing imaginal disc
48. The transcription factor Schnurri plays a dual role in mediating Dpp signaling during embryogenesis
49. Schnurri interacts with mad in a dpp-dependent manner
50. Drosophila CBP represses the transcription factor TCF to antagonize Wingless signalling
51. Smad proteins act in combination with synergistic and antagonistic regulators to target Dpp responses to the Drosophila mesoderm
52. Brinker is a sequence-specific transcriptional repressor in the Drosophila embryo