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Volumn 15, Issue 10, 1999, Pages 396-402

Morphogen gradients: New insights from DPP

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; BRINKER PROTEIN; CANCER GROWTH FACTOR; MORPHOGEN; UNCLASSIFIED DRUG;

EID: 0033214367     PISSN: 01689525     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-9525(99)01854-5     Document Type: Review
Times cited : (105)

References (46)
  • 1
    • 0014593403 scopus 로고
    • Positional information and the spatial pattern of cellular differentiation
    • Wolpert, L (1969) Positional information and the spatial pattern of cellular differentiation. J. Theor.Biol.25,1-47
    • (1969) J. Theor.Biol. , vol.25 , pp. 1-47
    • Wolpert, L.1
  • 2
    • 0031213842 scopus 로고    scopus 로고
    • Morphogens and pattern formation
    • Neumann, C. and Cohen, S. (1997) Morphogens and pattern formation. BioEssays 19,721-729
    • (1997) BioEssays , vol.19 , pp. 721-729
    • Neumann, C.1    Cohen, S.2
  • 3
    • 0032515012 scopus 로고    scopus 로고
    • Spatially restricted activation of the SAX receptor bySCW modulates DPP/TKV signaling in Drosophila dorsal-ventral patterning
    • Neul, J.L and Ferguson, El. (1998) Spatially restricted activation of the SAX receptor bySCW modulates DPP/TKV signaling in Drosophila dorsal-ventral patterning. Cell 95, 483-494
    • (1998) Cell , vol.95 , pp. 483-494
    • Neul, J.L.1    Ferguson, E.2
  • 4
    • 0032514852 scopus 로고    scopus 로고
    • Interpretation of a BMP activity gradient in Drosophila embryos depends on synergistic signaling by two Type I receptors, SAX and TKV
    • Nguyen, M. et al. (1998) Interpretation of a BMP activity gradient in Drosophila embryos depends on synergistic signaling by two Type I receptors, SAX and TKV. Cell 95, 495-506
    • (1998) Cell , vol.95 , pp. 495-506
    • Nguyen, M.1
  • 5
    • 0031766027 scopus 로고    scopus 로고
    • Synergistic signaling by two BMP ligands through the SAX and TKV receptors controls wing growth and patterning in Drosophila
    • Haerry, I.E. et al. (1998) Synergistic signaling by two BMP ligands through the SAX and TKV receptors controls wing growth and patterning in Drosophila. Development 125, 3977-3987
    • (1998) Development , vol.125 , pp. 3977-3987
    • Haerry, I.E.1
  • 6
    • 0032425036 scopus 로고    scopus 로고
    • Dpp receptor levels contribute to shaping the Dpp morphogen gradient in the Drosophila wing imaginai disc
    • Lecuit, T. and Cohen, S.M. (1998) Dpp receptor levels contribute to shaping the Dpp morphogen gradient in the Drosophila wing imaginai disc. Development 125, 4901-4907
    • (1998) Development , vol.125 , pp. 4901-4907
    • Lecuit, T.1    Cohen, S.M.2
  • 7
    • 0033582753 scopus 로고    scopus 로고
    • The Drosophila gene tonterreveals a novel mechanism of Dpp target gene regulation
    • Jazwinska, A. et al. (1999) The Drosophila gene tonterreveals a novel mechanism of Dpp target gene regulation. Cell 96, 563-573
    • (1999) Cell , vol.96 , pp. 563-573
    • Jazwinska, A.1
  • 8
    • 0033582646 scopus 로고    scopus 로고
    • Transducing the Dpp morphogen gradient in the wing of Drosophila: Regulation of Dpp targets by brinker
    • Campbell, G. and Tomlinson, A. (1999) Transducing the Dpp morphogen gradient in the wing of Drosophila: regulation of Dpp targets by brinker. Cell 96,553-562
    • (1999) Cell , vol.96 , pp. 553-562
    • Campbell, G.1    Tomlinson, A.2
  • 9
    • 0033580437 scopus 로고    scopus 로고
    • To'nferis a target of Dpp in Drosophila that negatively regulates Dpp-dependent genes
    • Minami, M. et al. (1999) to'nferis a target of Dpp in Drosophila that negatively regulates Dpp-dependent genes. Nature 398, 242-246
    • (1999) Nature , vol.398 , pp. 242-246
    • Minami, M.1
  • 10
    • 0033119776 scopus 로고    scopus 로고
    • Local inhibition and longrange enhancement of Dpp signal transduction by Sog
    • Ashe, Hi. and Levine, M. (1999) Local inhibition and longrange enhancement of Dpp signal transduction by Sog. Nature 398, 427-431
    • (1999) Nature , vol.398 , pp. 427-431
    • Ashe, Hi.1    Levine, M.2
  • 11
    • 0033612317 scopus 로고    scopus 로고
    • Cytonemes: Cellular processes that project to the principal signaling center in Drosophila imaginai discs
    • Ramirez-Weber, F-A. and Kornberg, T.B. (1999) Cytonemes: cellular processes that project to the principal signaling center in Drosophila imaginai discs. Cell 97,599-607
    • (1999) Cell , vol.97 , pp. 599-607
    • Ramirez-Weber, F.-A.1    Kornberg, T.B.2
  • 12
    • 0029894568 scopus 로고    scopus 로고
    • Direct and long-range action of a DPP morphogen gradient
    • Nellen, D. et al. (1996) Direct and long-range action of a DPP morphogen gradient. Cell 85, 357-368
    • (1996) Cell , vol.85 , pp. 357-368
    • Nellen, D.1
  • 13
    • 0029967209 scopus 로고    scopus 로고
    • Two distinct mechanisms for longrange patterning by Decapentaplegic in the Drosophila wing
    • Lecuit, T. etal. (1996) Two distinct mechanisms for longrange patterning by Decapentaplegic in the Drosophila wing. Nature 381, 387-393
    • (1996) Nature , vol.381 , pp. 387-393
    • Lecuit, T.1
  • 14
    • 0023408868 scopus 로고
    • Decapentaplegic transcripts are localized along the dorsal-ventral axis of the Drosophila embryo
    • St Johnston, R.D. and Gelbart, W.M. (1987) Decapentaplegic transcripts are localized along the dorsal-ventral axis of the Drosophila embryo. EMBOJ. 6, 2785-2791
    • (1987) EMBOJ , vol.6 , pp. 2785-2791
    • St Johnston, R.D.1    Gelbart, W.M.2
  • 15
    • 0023424002 scopus 로고
    • The decapentaplegic gene is required for dorsal-ventral patterning of the Drosophila embryo
    • Irish, V.F. and Gelbart, W.M. (1987) The decapentaplegic gene is required for dorsal-ventral patterning of the Drosophila embryo. Genes Dev. 1, 868-879
    • (1987) Genes Dev , vol.1 , pp. 868-879
    • Irish, V.F.1    Gelbart, W.M.2
  • 16
    • 0026451642 scopus 로고
    • Decapentaplegic acts as a morphogen to organize dorsal-ventral pattern in the Drosophila embryo
    • Ferguson, El. and Anderson, K.V. (1992) Decapentaplegic acts as a morphogen to organize dorsal-ventral pattern in the Drosophila embryo. Cell 71, 451-461
    • (1992) Cell , vol.71 , pp. 451-461
    • Ferguson, E.A.1    Anderson, K.V.2
  • 17
    • 0027467829 scopus 로고
    • An activity gradient of decapentaplegic is necessary for the specification of dorsal pattern elements in the Drosophila embryo
    • Wharton, K.A. et al. (1993) An activity gradient of decapentaplegic is necessary for the specification of dorsal pattern elements in the Drosophila embryo. Development 117, 807-822
    • (1993) Development , vol.117 , pp. 807-822
    • Wharton, K.A.1
  • 18
    • 0026598187 scopus 로고
    • Localized enhancement and repression of the activity of the TGF- family member, decapentaplegic, is necessary for dorsal-ventral pattern formation in the Drosophila embryo
    • Ferguson, El. and Anderson, K.V. (1992) Localized enhancement and repression of the activity of the TGF- family member, decapentaplegic, is necessary for dorsal-ventral pattern formation in the Drosophila embryo. Development 114,583-597
    • (1992) Development , vol.114 , pp. 583-597
    • Ferguson, E.1    Anderson, K.V.2
  • 19
    • 0028135238 scopus 로고
    • The screw gene encodes a ubiquitously expressed member of the TGF-β family required for specification of dorsal cell fates in the Drosophila embryo
    • Arora, K. et al. (1994) The screw gene encodes a ubiquitously expressed member of the TGF-β family required for specification of dorsal cell fates in the Drosophila embryo. Genes Dev. 8, 2588-2601
    • (1994) Genes Dev , vol.8 , pp. 2588-2601
    • Arora, K.1
  • 20
    • 0031825725 scopus 로고    scopus 로고
    • TGF-β/BMPsuperfamily members, Gbb-60A and Dpp, cooperate to provide pattern information and establish cell identity in the Drosophila wing
    • Khalsa, O. et at. (1998) TGF-β/BMPsuperfamily members, Gbb-60A and Dpp, cooperate to provide pattern information and establish cell identity in the Drosophila wing. Development 125, 2723-2734
    • (1998) Development , vol.125 , pp. 2723-2734
    • Khalsa, O.1
  • 21
    • 0031438047 scopus 로고    scopus 로고
    • TGF-β signalling from cell membrane to nucleus through SMAD proteins
    • Heldin, C.H. et al. (1997) TGF-β signalling from cell membrane to nucleus through SMAD proteins. Nature 390, 465-471
    • (1997) Nature , vol.390 , pp. 465-471
    • Heldin, C.H.1
  • 22
    • 0028170226 scopus 로고
    • Mechanism of activation of the TGF-β receptor
    • Wrana, J.L et al. (1994) Mechanism of activation of the TGF-β receptor. Nature 370, 341-347
    • (1994) Nature , vol.370 , pp. 341-347
    • Wrana, J.L.1
  • 23
    • 0028141433 scopus 로고
    • Identification of two bone morphogenetic protein type I receptors in Drosophila and evidence that Brk25D is a Decapentaplegic receptor
    • Penton, A. et al. (1994) Identification of two bone morphogenetic protein type I receptors in Drosophila and evidence that Brk25D is a Decapentaplegic receptor. Cell 78, 239-250
    • (1994) Cell , vol.78 , pp. 239-250
    • Penton, A.1
  • 24
    • 0027953772 scopus 로고
    • Receptorserine/threonine kinases implicated in the control of Drosophila body pattern by Decapentaplegic
    • Nellen, D. et al. (1994) Receptorserine/threonine kinases implicated in the control of Drosophila body pattern by Decapentaplegic. Cell 78, 225-237
    • (1994) Cell , vol.78 , pp. 225-237
    • Nellen, D.1
  • 25
    • 0028103859 scopus 로고
    • Characterization and relationship of Dpp receptors encoded by the saxophone and thick veins genes in Drosophila
    • Brummel, T.J. et al. (1994) Characterization and relationship of Dpp receptors encoded by the saxophone and thick veins genes in Drosophila. Cell 78, 251-261
    • (1994) Cell , vol.78 , pp. 251-261
    • Brummel, T.J.1
  • 26
    • 0028907069 scopus 로고
    • Drosophila Dpp signaling is mediated bythepunfgene product: A dual ligand-bindingtype II receptor of the TGF β receptor family
    • Letsou, A. et al. (1995) Drosophila Dpp signaling is mediated bythepunfgene product: a dual ligand-bindingtype II receptor of the TGF β receptor family. Cell 80, 899-908
    • (1995) Cell , vol.80 , pp. 899-908
    • Letsou, A.1
  • 27
    • 0028923022 scopus 로고
    • An absolute requirement for both the type II and type I receptors, punt and thick veins, for dpp signaling in vivo
    • Ruberte, E. et al. (1995) An absolute requirement for both the type II and type I receptors, punt and thick veins, for dpp signaling in vivo. Cell 80, 889-897
    • (1995) Cell , vol.80 , pp. 889-897
    • Ruberte, E.1
  • 28
    • 0031024795 scopus 로고    scopus 로고
    • Signaling through both type I DPP receptors is required for anterior-posterior patterning of the entire Drosophila wing
    • Singer, M.A. et al. (1997) Signaling through both type I DPP receptors is required for anterior-posterior patterning of the entire Drosophila wing. Development 124,79-89
    • (1997) Development , vol.124 , pp. 79-89
    • Singer, M.A.1
  • 29
    • 0032524323 scopus 로고    scopus 로고
    • The interpretation of position in a morphogen gradient as revealed by occupancy of activin receptors
    • Dyson, S. and Gurdon, J.B. (1998) The interpretation of position in a morphogen gradient as revealed by occupancy of activin receptors. Cell 93,557-568
    • (1998) Cell , vol.93 , pp. 557-568
    • Dyson, S.1    Gurdon, J.B.2
  • 30
    • 0028006985 scopus 로고
    • Dorsal-ventral patterning of the Drosophila embryo depends on a putative negative growth factor encoded by the short gastrulation gene
    • François, V. et al. (1994) Dorsal-ventral patterning of the Drosophila embryo depends on a putative negative growth factor encoded by the short gastrulation gene. Genes Dev. 8, 2602-2616
    • (1994) Genes Dev , vol.8 , pp. 2602-2616
    • François, V.1
  • 31
    • 0028834047 scopus 로고
    • Xenopuschordin and Drosophila short gastrulation genes encode homologous proteins functioning in dorsal-ventral axis formation
    • François, V. and Bier, E. (1995) Xenopuschordin and Drosophila short gastrulation genes encode homologous proteins functioning in dorsal-ventral axis formation. Cell 80, 19-20
    • (1995) Cell , vol.80 , pp. 19-20
    • François, V.1    Bier, E.2
  • 32
    • 0029077979 scopus 로고
    • A conserved system for dorsal-ventral patterning in insects and vertebrates involving sog and chordin
    • Holley, S.A. et at. (1995) A conserved system for dorsal-ventral patterning in insects and vertebrates involving sog and chordin. Nature 376, 249-253
    • (1995) Nature , vol.376 , pp. 249-253
    • Holley, S.A.1
  • 33
    • 0030598867 scopus 로고    scopus 로고
    • Dorsoventral patterning in Xenopus: Inhibition of ventral signals by direct binding of chordin to BMP-4
    • Piccolo, S. et al. (1996) Dorsoventral patterning in Xenopus: inhibition of ventral signals by direct binding of Chordin to BMP-4. CW/86, 589-598
    • (1996) Cell , vol.86 , pp. 589-598
    • Piccolo, S.1
  • 34
    • 0025986820 scopus 로고
    • The Drosophila dorsal-ventral patterning gene tolloid is related to human bone morphogenetic protein 1
    • Shimell, M.J. et at. (1991) The Drosophila dorsal-ventral patterning gene tolloid is related to human bone morphogenetic protein 1. Cell 67, 469-481
    • (1991) Cell , vol.67 , pp. 469-481
    • Shimell, M.J.1
  • 35
    • 0030671306 scopus 로고    scopus 로고
    • Production of a DPP activity gradient in the early Drosophila embryo through the opposing actions of the SOG and TLD proteins
    • Marqués, G. et al. (1997) Production of a DPP activity gradient in the early Drosophila embryo through the opposing actions of the SOG and TLD proteins. Cell 91, 417-426
    • (1997) Cell , vol.91 , pp. 417-426
    • Marqués, G.1
  • 36
    • 0023789143 scopus 로고
    • Short gastrulation, a mutation causing delays in stage-specific cell shape changes during gastrulation in Drosophila melanogaster
    • Zusman, S.B. et al. (1988) Short gastrulation, a mutation causing delays in stage-specific cell shape changes during gastrulation in Drosophila melanogaster. Dev. Biol. 129, 417-427
    • (1988) Dev. Biol. , vol.129 , pp. 417-427
    • Zusman, S.B.1
  • 37
    • 0030598871 scopus 로고    scopus 로고
    • The Xenopusdorsalizing factor Noggin ventralizes Drosophila embryos by preventing DPP from activating its receptor
    • Holley, S.A. et al. (1996) The Xenopusdorsalizing factor Noggin ventralizes Drosophila embryos by preventing DPP from activating its receptor. Cell 86,607-617
    • (1996) Cell , vol.86 , pp. 607-617
    • Holley, S.A.1
  • 38
    • 0030872367 scopus 로고    scopus 로고
    • Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic
    • Kim, J. et al. (1997) Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic. Nature 388, 304-308
    • (1997) Nature , vol.388 , pp. 304-308
    • Kim, J.1
  • 39
    • 0030863365 scopus 로고    scopus 로고
    • Daughters against dpp modulates dpp organizing activity in Drosophila wing development
    • Tsuneizumi, K. et al. (1997) Daughters against dpp modulates dpp organizing activity in Drosophila wing development. Nature 389, 627-631
    • (1997) Nature , vol.389 , pp. 627-631
    • Tsuneizumi, K.1
  • 40
    • 0031876205 scopus 로고    scopus 로고
    • Interplay of signal mediators of Decapentaplegic (Dpp): Molecular characterization of Mothers against dpp, Medea, and Daughters against dpp
    • Inoue, H. et al. (1998) Interplay of signal mediators of Decapentaplegic (Dpp): molecular characterization of Mothers against dpp, Medea, and Daughters against dpp. Mol. Biol. Cell'3, 2145-2156
    • (1998) Mol. Biol. Cell , vol.3 , pp. 2145-2156
    • Inoue, H.1
  • 41
    • 0030800352 scopus 로고    scopus 로고
    • An anteroposterior Dorsal gradient in the Drosophila embryo
    • Huang, A.M. et al. (1997) An anteroposterior Dorsal gradient in the Drosophila embryo. Genes Dev. 11,1963-1973
    • (1997) Genes Dev , vol.11 , pp. 1963-1973
    • Huang, A.M.1
  • 42
    • 0030667930 scopus 로고    scopus 로고
    • SmadS mediates the signaling of the ALK-2 receptor serine kinase
    • Chen, Y. et al. (1997) SmadS mediates the signaling of the ALK-2 receptor serine kinase. Proc. Natl. Acad. Sci. U. S. A. 94, 12938-12943
    • (1997) Proc. Natl. Acad. Sci. U. S. A. , vol.94 , pp. 12938-12943
    • Chen, Y.1
  • 43
    • 0032475884 scopus 로고    scopus 로고
    • Specific activation of Smadl signaling pathways by the BMP? type I receptor, ALK2
    • Macias-Silva, M. et al. (1998) Specific activation of Smadl signaling pathways by the BMP? type I receptor, ALK2. J. Biol. Chem. 273,25628-25636
    • (1998) J. Biol. Chem. , vol.273 , pp. 25628-25636
    • Macias-Silva, M.1
  • 44
    • 0033524945 scopus 로고    scopus 로고
    • Smadl recognition and activation bytheALKl group of transforming growth factor-β family receptors
    • Chen, Y.G. and Massague, J. (1999) Smadl recognition and activation bytheALKl group of transforming growth factor-β family receptors. J. Biol. Chem. 274, 3672-3677
    • (1999) J. Biol. Chem. , vol.274 , pp. 3672-3677
    • Chen, Y.G.1    Massague, J.2
  • 45
    • 0032481351 scopus 로고    scopus 로고
    • The L3 loop: A structural motif determining specific interactions between SMAD proteins and TGF-β receptors
    • Lo, R.S. et al. (1998) The L3 loop: a structural motif determining specific interactions between SMAD proteins and TGF-β receptors. EMBOJ. 17, 996-1005
    • (1998) EMBOJ , vol.17 , pp. 996-1005
    • Lo, R.S.1
  • 46
    • 0031697799 scopus 로고    scopus 로고
    • The L45 loop in type I receptors for TGF-β family members is a critical determinant in specifying Smad isoform activation
    • Persson, U. et al. (1998) The L45 loop in type I receptors for TGF-β family members is a critical determinant in specifying Smad isoform activation. Febs Lett. 434, 83-87
    • (1998) Febs Lett , vol.434 , pp. 83-87
    • Persson, U.1


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