Electrophysiologic parameters and predisposing factors in the generation of drug-induced Torsade de Pointes arrhythmias

Pharmacology and Therapeutics

Volumn 92, Issue 2-3, 2001, Pages 109-122

  Vos, Marc A ^a   Van Opstal, Jurren M ^a   Leunissen, Jet D M ^a   Verduyn, S Cora ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

Acquired long QT syndrome; Antiarrhythmic drugs; Dispersion of repolarization; Sudden cardiac death; Ventricular arrhythmias

Indexed keywords

1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 [2 (TRIFLUOROMETHYL)PHENYL] 3 PYRIDINECARBOXYLIC ACID METHYL ESTER; 2 (2,4 DIFLUOROPHENYL) 1 [3 [2 [4 (2,2,3,3 TETRAFLUOROPROPOXY)PHENYL]VINYL] 1,2,4 TRIAZOL 1 YL] 3 (1,2,4 TRIAZOL 1 YL) 2 PROPANOL; ALMOKALANT; ANTHOPLEURIN A; ASTEMIZOLE; CESIUM; CISAPRIDE; CLARITHROMYCIN; CLOFILIUM; DISOPYRAMIDE; ERYTHROMYCIN; ESMOLOL; FLUNARIZINE; HALOFANTRINE; HALOTHANE; IBUTILIDE; KETOCONAZOLE; MEFLOQUINE; METHOXAMINE; OXATOMIDE; PENTOBARBITAL; PROCAINAMIDE; PROPRANOLOL; QUINIDINE; SOTALOL; SPARFLOXACIN; SULFAMETHOXAZOLE;

ANESTHESIA; ATRIOVENTRICULAR BLOCK; BETA ADRENERGIC RECEPTOR BLOCKING; BRADYCARDIA; DISEASE PREDISPOSITION; DOSE RESPONSE; DRUG CLEARANCE; DRUG SAFETY; ELECTROCARDIOGRAPHY; ELECTROPHYSIOLOGY; ELECTROSTIMULATION; EXTRASYSTOLE; GENDER; HEART FAILURE; HEART LEFT VENTRICLE HYPERTROPHY; HEART PACING; HEART REPOLARIZATION; HUMAN; HYPOKALEMIA; HYPOMAGNESEMIA; INCIDENCE; LONG QT SYNDROME; NONHUMAN; PRIORITY JOURNAL; QT INTERVAL; REVIEW; TORSADE DES POINTES;

ANTI-ARRHYTHMIA AGENTS; DEATH, SUDDEN, CARDIAC; DRUG THERAPY; ELECTROCARDIOGRAPHY; ELECTROPHYSIOLOGY; FEMALE; HUMANS; MALE; RISK FACTORS; SEX FACTORS; TORSADES DE POINTES;

EID: 0035726691     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0163-7258(01)00162-0     Document Type: Review

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