Protective effects of red wine polyphenolic compounds on the cardiovascular system

Experimental and Clinical Cardiology

Volumn 6, Issue 3, 2001, Pages 153-158

  Zenebe, Woineshet ^a   Pechánová, Olga ^a   Bernátová, Iveta ^a  

^a INSTITUTE OF CHEMISTRY   (Slovakia)

Author keywords

Anti ischemic effect; Antioxidant activity; Antithrombic effect; Flavonoids; Polyphenols; Vasorelaxant properties

Indexed keywords

3,4 TRIHYDROXYSTILBEN DERIVATIVE; ACETYLSALICYLIC ACID; ALPHA TOCOPHEROL; ANTHOCYANIDIN; ANTHOCYANIN DERIVATIVE; APIGENIN; ASCORBIC ACID; BUTYLCRESOL; CATECHIN; CHALCONE; CHROMAN DERIVATIVE; CYANIDIN; EPICATECHIN; FLAVANE; FLAVANONE; FLAVONE; FLAVONOID; FLAVONOLE; N(G) METHYLARGININE; N(G) NITROARGININE METHYL ESTER; NARINGENIN; PHLORETIN; POLYPHENOL DERIVATIVE; PROVINOL; PYCNOGENOL; QUERCETIN; RESVERATROL; RUTOSIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ALLERGY; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ANTIVIRAL ACTIVITY; BIOAVAILABILITY; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CARDIOVASCULAR SYSTEM; CELL PROLIFERATION; CONFERENCE PAPER; CORONARY ARTERY DISEASE; DRUG ACTIVITY; EPIDEMIOLOGICAL DATA; FOOD DRUG INTERACTION; FOOD INTAKE; FRANCE; HEART PROTECTION; HUMAN; INCIDENCE; ISCHEMIA; NONHUMAN; PHYTOCHEMISTRY; POPULATION RESEARCH; STRUCTURE ANALYSIS; THROMBOSIS; VASODILATATION; WINE;

EID: 0035571891     PISSN: 12056626     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (56)

1. Mortality associated with moderate intakes of wine, beer, or spirits
2. Protection from cardiovascular disease by wine and its derived products
3. Why heart disease mortality is low in France: The time lag explanation
4. Inhibition of oxidation of human low-density lipoprotein by phenolic substances in red wine
5. 2+-oxidizability: Possible explanation by phenolic location
6. Review of the biology of quercetin and related bioflavonoids
7. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor
8. Modulation of haemostatic function and prevention of experimental thrombosis by red wine in rats: A role for increased nitric oxide production
9. Endothelium-dependent vasorelaxing activity of wine and other grape products
10. Nitric oxide production and endothelium-dependent vasorelaxation induced by wine polyphenols in rat aorta
11. Wine as a biological fluid; History, production and role in disease prevention
12. The effect of plant flavonoids on mammalian cells: Implications for inflammation, heart disease and cancer
13. Relaxation to flavones and flavonols in rat isolated thoracic aorta: Mechanism of action and structure-activity relationships
14. The pathogenesis of coronary artery disease and the acute coronary syndromes
15. The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: Implications for protection against coronary heart disease
16. Interference of some flavonoids and nonsteroidal antiinflammatory drugs with oxidative metabolisms of arachidonic acid by human platelets and neutrophils
17. Administration of wine and grape juice inhibits in vivo platelet activity and thrombosis in stenosed canine coronary arteries
18. Wine and polyphenols related to platelet aggregation and antithrombosis
19. Moderate alcohol intake, increased levels of high-density lipoprotein and its subfractions and decreased risk of myocardial infarction
20. Antithrombotic effect of flavonoids in red wine
21. Resveratrol, a polyphenolic compound found in wine, inhibits tissue factor expression in vascular cells: A possible mechanism for the cardiovascular benefits associated with moderate consumption of wine
22. Free radicals, antioxidants and human disease: Where are we now?
23. Lipid peroxidation: Its mechanism, measurement, and significance
24. Flavonoids as antioxidants
25. Structure-antioxidant activity relationships of flavonoids and isoflavonoids
26. Reduced progression of atherosclerosis in apolipoprotein E-deficient mice following consumption of red wine, or its polyphenols quercetin or catechin, is associated with reduced susceptibility of LDL to oxidation and aggregation
27. Flavonoids inhibit the oxidative modification of low-density lipoproteins by macrophages
28. Inhibition of human low-density lipoprotein oxidation by flavonoids in red wine and grape juice
29. Consumption of red wine polyphenols reduces the susceptibility of low-density lipoproteins to oxidation in vivo
30. Alcohol-free red wine enhances plasma antioxidant capacity in humans
31. The relative antioxidant activities of plant-derived polyphenolic flavonoids
32. Does diet or alcohol explain the French paradox?
33. Cardioprotective effect of grape seed proanthocyanidin against ischemic reperfusion injury
34. Nitric oxide/carbon monoxide: A free radical-dependent molecular switch for myocardial preservation during ischemic arrest
35. Plasma concentration of soluble intercellular adhesion molecule 1 and risks of future myocardial infarction in apparently healthy men
36. Effect of different inotropes with antioxidant properties on acute regional myocardial ischemia in isolated rabbit hearts
37. Flavone improves functional recovery after ischemia in isolated reperfused rabbit hearts
38. Changes in the xanthine dehydrogenase/xanthine oxidase ratio in the rat kidney subjected to ischemia-reperfusion stress: Preventive effect of some flavonoids
39. Effects of flavonoids on xanthine oxidation as well as on cytochrome C reduction by milk xanthine oxidase
40. Effect of flavonoids on the outcome of myocardial mitochondrial ischemia/reperfusion injury
41. L-NAME-induced hypertension: Possibilities of its prevention and regression
42. Mechanism of endothelial nitric oxide-dependent vasorelaxation induced by wine polyphenols in rat thoracic aorta
43. Inhibitory effects of phloretin on histamine release from isolated rat mast cells
44. Quercetin: An inhibitor of antigen-induced human basophil histamine release
45. Endothelial NO release caused by red wine polyphenols
46. 2+ increase and nitric oxide production in vascular endothelial cells: Involvement of phospholipase C, tyrosine kinase and G proteins
47. Endothelial NO release caused by red wine polyphenols with specific structure
48. Natural dietary polyphenolic compounds caused endothelium-dependent vasorelaxation in rat thoracic aorta
49. Myocardial effects of flavonoids from Crataegus species
50. Vasorelaxant effect of purified green tea epicatechin derivatives in rat mesenteric artery
51. Structure/activity studies of flavonoids as inhibitors of cyclic AMP phosphodiesterase and relationship to quantum chemical indices
52. Regression of L-NAME-induced hypertension by red wine polyphenol compounds
53. Extract of wine phenolics improves aortic biomechanical properties in stroke-prone spontaneously hypertensive rats (SHRSP)
54. The effect of tea polyphenols on cardiovascular disease
55. Wine polyphenols decrease blood pressure, improve NO vasodilatation and induce gene expression
56. Reduction of chronic psychosocial hypertension in mice by decaffeinated tea