Role of Janus kinase-2 in insulin-mediated phosphorylation and inactivation of protein phosphatase-2A and its impact on upstream insulin signalling components

Biochemical Journal

Volumn 344, Issue 3, 1999, Pages 895-901

  Begum, Najma ^a,b   Ragolia, Louis ^a  

^a WINTHROP UNIVERSITY HOSPITAL   (United States)

^b STONY BROOK UNIVERSITY   (United States)

Author keywords

Insulin resistance; IRS 1; PI 3 kinase; TNF

Indexed keywords

ENZYME INHIBITOR; INSULIN; JANUS KINASE; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOPROTEIN PHOSPHATASE 2A; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INACTIVATION; IMMUNOPRECIPITATION; INSULIN RESISTANCE; MUSCLE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; SKELETAL MUSCLE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADIPOCYTES; ANIMALS; CELL LINE; CYCLIC AMP; ENZYME ACTIVATION; ENZYME INHIBITORS; INSULIN; JANUS KINASE 2; MUSCLE, SKELETAL; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHORYLATION; PRECIPITIN TESTS; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; RATS; SIGNAL TRANSDUCTION; TYRPHOSTINS;

EID: 0033572997     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3440895     Document Type: Article

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