Striated muscle-specific β(1D)-integrin and FAK are involved in cardiac myocyte hypertrophic response pathway

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 279, Issue 6 48-6, 2000, Pages

  Pham, Can G ^a   Harpf, Alice E ^a   Keller, Rebecca S ^b   Vu, Hoa T ^a   Shai, Shaw Yung ^a   Loftus, Joseph C ^b   Ross, Robert S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b MAYO CLINIC   (United States)

Author keywords

Cell signaling; Extracellular matrix; Focal adhesion kinase; Heart; Neonatal rat ventricular myocytes

Indexed keywords

ATRIAL NATRIURETIC FACTOR; BETA1 INTEGRIN; BETA1D INTEGRIN; BIOLOGICAL MARKER; FOCAL ADHESION KINASE; LUCIFERASE; PROTEIN KINASE P60; UNCLASSIFIED DRUG;

ALPHA ADRENERGIC STIMULATION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL ADHESION; CELL GROWTH; CELL SIZE; CONTROLLED STUDY; ENZYME BINDING; ENZYME PHOSPHORYLATION; EXTRACELLULAR MATRIX; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; SIGNAL TRANSDUCTION; TISSUE CULTURE;

EID: 0034533580     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.2000.279.6.h2916     Document Type: Article

References (70)

1. Regulation of development and differentiation by the extracellular matrix
2. Transmembrane signal transduction by integrin cytoplasmic domains expressed in single-subunit chimeras
3. 1 exon D define distinct roles for integrin splice variants in heart function and embryonic development
4. Beta(1D) integrin inhibits cell cycle progression in normal myoblasts and fibroblasts
5. Muscle beta(1D) integrin reinforces the cytoskeleton-matrix link: Modulation of integrin adhesive function by alternative splicing
6. Differential onset of expression of alpha 7 and beta 1D integrins during mouse heart and skeletal muscle development
7. Melusin is a new muscle-specific interactor for beta(1) integrin cytoplasmic domain
8. 1 integrin
9. 'Inside-out' signal transduction inhibited by isolated integrin cytoplasmic domains
10. Integrins and signal transduction pathways: The road taken
11. Signal transduction by integrin receptors for extracellular matrix: Cooperative processing of extracellular information
12. Novel functions for calreticulin: Interaction with integrins and modulation of gene expression?
13. Integrins and signal transduction
14. Endothelin-induced cardiac myocyte hypertrophy: Role for focal adhesion kinase
15. Fibronectin expression during physiological and pathological cardiac growth
16. Differentiation and integrity of cardiac muscle cells are impaired in the absence of beta 1 integrin
17. Alternatively spliced variants: A new view of the integrin cytoplasmic domain
18. Mechanical loading regulates expression of talin and its mRNA, which are concentrated at myotendinous junctions
19. Oncogenic src, raf, and ras stimulate a hypertrophic pattern of gene expression and increase cell size in neonatal rat ventricular myocytes
20. Fibronectins are essential for heart and blood vessel morphogenesis but are dispensable for initial specification of precursor cells
21. The mitogen-activated protein kinase kinase MEK1 stimulates a pattern of gene expression typical of the hypertrophic phenotype in rat ventricular cardiomyocytes
22. Cellular mechanisms of cardiac hypertrophy
23. Adenovirus-mediated transfer of the muscle glycogen phosphorylase gene into hepatocytes confers altered regulation of glycogen metabolism
24. Manipulation of adenovirus vectors
25. A simplified system for generating recombinant adenoviruses
26. Regulation of cell adhesion receptors by transforming growth factor-beta. Concomitant regulation of integrins that share a common beta 1 subunit
27. The role of beta 1 integrin in spreading and myofibrillogenesis in neonatal rat cardiomyocytes in vitro
28. Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress
29. 1 and laminin can serve as components of attachment complex mediating contraction force transmission from cardiomyocytes to extracellular matrix
30. Integrins as mechanochemical transducers
31. Cellular basis of mechanotransduction
32. Coregulation of the atrial natriuretic factor and cardiac myosin light chain-2 genes during alpha-adrenergic stimulation of neonatal rat ventricular cells. Identification of cis sequences within an embryonic and a constitutive contractile protein gene which mediate inducible expression
33. Stretching cardiac myocytes stimulates protooncogene expression
34. Association of tyrosine-phosphorylated c-Src with the cytoskeleton of hypertrophying myocardium
35. G(q)- and ras-dependent pathways mediate hypertrophy of neonatal rat ventricular myocytes following alpha 1-adrenergic stimulation
36. 1 integrin binding protein (MIBP) that modulates myogenic differentiation
37. Fluid shear stress activation of focal adhesion kinase. Linking to mitogen-activated protein kinases
38. Rack1, a receptor for activated protein kinase C, interacts with integrin beta subunit
39. Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2C
40. Cell anchorage permits efficient signal transduction between ras and its downstream kinases
41. Insulin-like growth factor II induces DNA synthesis in fetal ventricular myocytes in vitro
42. Integrin-mediated cell adhesion: The extracellular face
43. Transition from hypertrophy to failure
44. Protein measurement with the Folin phenol reagent
45. Disruption of integrin function and induction of tyrosine phosphorylation by the autonomously expressed beta 1 integrin cytoplasmic domain
46. Transforming growth factor-beta response elements of the skeletal alpha-actin gene. Combinatorial action of serum response factor, YY1, and the SV40 enhancer-binding protein, TEF- 1
47. Switching from differentiation to growth in hepatocytes: Control by extracellular matrix
48. Outside-in signaling of fibronectin stimulates cardiomyocyte hypertrophy in cultured neonatal rat ventricular myocytes
49. Integrin-linked kinase and the LIM-only protein PINCH, interact to regulate cardiac expression of skeletal alpha-actin
50. Integrin beta cytoplasmic domains differentially bind to cytoskeletal proteins
51. 1 integrins participate in the hypertrophic response of rat ventricular myocytes
52. Load effects on gene expression during cardiac hypertrophy
53. Mechanotransduction in stretch-induced hypertrophy of cardiac myocytes
54. 1-adrenergic receptor signaling in cardiomyocytes. Dissociation of Ras and Rho pathways
55. Autonomous expression of a noncatalytic domain of the focal adhesion-associated protein tyrosine kinase pp125FAK
56. Signaling through focal adhesion kinase
57. Evidence for in vivo phosphorylation of the Grb2 SH2-domain binding site on focal adhesion kinase by Src-family protein-tyrosine kinases
58. Hypoxia induces activation and subcellular translocation of focal adhesion kinase [p125(FAK)] in cultured rat cardiac myocytes
59. Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration
60. 'Stress-responsive' mitogen-activated protein kinases (c-Jun N-terminal kinases and p38 mitogen-activated protein kinases) in the myocardium
61. Molecular mechanisms of myocardial remodeling
62. Vascular endothelial growth factor induces activation and subcellular translocation of focal adhesion kinase [p125(FAK)] in cultured rat cardiac myocytes
63. Expression of collagen binding integrins during cardiac development and hypertrophy
64. MAP kinase- and Rho-dependent signals interact to regulate gene expression but not actin morphology in cardiac muscle cells
65. Spatial and temporal expression of the beta(1D) integrin during mouse development
66. A novel beta 1 integrin isoform produced by alternative splicing: Unique expression in cardiac and skeletal muscle
67. Molecular mechanism of cardiac cellular hypertrophy by mechanical stress
68. Mechanical loading activates mitogen-activated protein kinase and S6 peptide kinase in cultured rat cardiac myocytes
69. A role for the p38 mitogen-activated protein kinase pathway in myocardial cell growth, sarcomeric organization, and cardiac-specific gene expression
70. Novel isoform of beta 1 integrin expressed in skeletal and cardiac muscle