The role of p53 in regulating antiviral T cell responses

Journal of Immunology

Volumn 167, Issue 3, 2001, Pages 1333-1337

  Grayson, J M ^a   Lanier, J G ^a   Altman, J D ^a   Ahmed, R ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53;

ANIMAL CELL; ANTIGEN SPECIFICITY; ANTIVIRAL ACTIVITY; APOPTOSIS; ARTICLE; CELL DEATH; CELL PROLIFERATION; EFFECTOR CELL; GENE MUTATION; HELPER CELL; IMMUNE RESPONSE; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MAJOR HISTOCOMPATIBILITY COMPLEX; MEMORY CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SUPPRESSOR CELL; VIRUS INFECTION;

EID: 0035421702     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.167.3.1333     Document Type: Article

References (30)

1. Apoptosis in cancer
2. Apoptosis and neurologic disease
3. p53: Death star
4. T antigen is bound to a host protein in SV40-transformed cells
5. Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
6. p53 mutations in human cancers
7. Identification of p53 as a sequence-specific DNA-binding protein
8. The p53 proto-oncogene can act as a suppressor of transformation
9. Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6
10. Counting antigen-specific CD8 T cells: A reevaluation of bystander activation during viral infection
11. Persistence of memory CD8 T cells in MHC class I-deficient mice
12. + T cells after antigen challenge in the absence of Fas (CD95)
13. Immune down-regulation and peripheral deletion of CD8 T cells does not require TNF receptor ligand interactions nor CD95 (Fas, APO-1)
14. TNF receptor 1 (TNFR1) and CD95 are not required for T cell deletion after virus infection but contribute to peptide-induced deletion under limited conditions
15. Selection of genetic variants of lymphocytic choriomeningitis virus in spleens of persistently infected mice: Role in suppression of cytotoxic T lymphocyte response and viral persistence
16. Evolution of the T cell repertoire during primary, memory, and recall responses to viral infection
17. p53, the cellular gatekeeper for growth an division
18. Cutting edge: Naive T cells masquerading as memory cells
19. + T cells in primary and secondary influenza pneumonia
20. Accelerated development and aging of the immune system in p53-deficient mice
21. p53 is required for radiation-induced apoptosis in mouse thymocytes
22. TCR-mediated death of mature T lymphocytes occurs in the absence of p53
23. The p53-dependent gamma ray response of GADD45
24. Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition
25. Ionizing radiation and chemotherapeutic drugs induce apoptosis in lymphocytes in the absence of Fas or FADD/MORT1 signaling: Implications for cancer therapy
26. p53-dependent and -independent pathways of apoptotic cell death in sepsis
27. Viral immune evasion due to persistence of activated T cells without effector function
28. + T cell clones in p53 mutant mice
29. Epstein-Barr virus infection and mitogen stimulation of normal B cells induces wild-type p53 without subsequent growth arrest or apoptosis
30. A common E2F-1 and p73 pathway mediates cell death induced by TCR activation