-
1
-
-
0028361220
-
Search for sepsis drugs goes on despite past failures
-
Stone, R. 1994. Search for sepsis drugs goes on despite past failures. Science 264:365.
-
(1994)
Science
, vol.264
, pp. 365
-
-
Stone, R.1
-
2
-
-
0017737597
-
Delayed hypersensitivity: Indicator of acquired failure of host defenses in sepsis and trauma
-
Meakins, J. L., J. B. Pietsch, O. Bubenick, R. Kelly, H. Rode, J. Gordon, and L. D. MacClean. 1977. Delayed hypersensitivity: indicator of acquired failure of host defenses in sepsis and trauma. Ann. Surg. 186:241.
-
(1977)
Ann. Surg.
, vol.186
, pp. 241
-
-
Meakins, J.L.1
Pietsch, J.B.2
Bubenick, O.3
Kelly, R.4
Rode, H.5
Gordon, J.6
MacClean, L.D.7
-
3
-
-
0028223194
-
Sepsis-induced apoptosis of the thymocytes in mice
-
Wang, S. D., K. J. Huang, Y. S. Lin, and H. Y. Lei. 1994. Sepsis-induced apoptosis of the thymocytes in mice. J. Immunol. 152:5014.
-
(1994)
J. Immunol.
, vol.152
, pp. 5014
-
-
Wang, S.D.1
Huang, K.J.2
Lin, Y.S.3
Lei, H.Y.4
-
4
-
-
0029880871
-
Differential induction of apoptosis in lymphoid tissue during sepsis: Variation in onset, frequency and nature of the mediators
-
Ayala, A., C. Herndon, D. Lehman, and I. H. Chaudry. 1996. Differential induction of apoptosis in lymphoid tissue during sepsis: variation in onset, frequency and nature of the mediators. Blood 87:4261.
-
(1996)
Blood
, vol.87
, pp. 4261
-
-
Ayala, A.1
Herndon, C.2
Lehman, D.3
Chaudry, I.H.4
-
5
-
-
0030739250
-
Apoptosis in lymphoid and parenchymal cells during sepsis: Findings in normal and T- and B-cell deficient mice
-
Hotchkiss, R. S., P. E. Swanson, J. P. Cobb, A. Jacobson, T. G. Buchman, and I. E. Karl. 1997. Apoptosis in lymphoid and parenchymal cells during sepsis: findings in normal and T- and B-cell deficient mice. Crit. Care Med. 25:1298.
-
(1997)
Crit. Care Med.
, vol.25
, pp. 1298
-
-
Hotchkiss, R.S.1
Swanson, P.E.2
Cobb, J.P.3
Jacobson, A.4
Buchman, T.G.5
Karl, I.E.6
-
6
-
-
0031170830
-
Mechanism of intestinal mucosal immune dysfunction following trauma-hemorrhage: Increased apoptosis associated with elevated Fas expression in peyer's patches
-
Xu, Y. X., A. Ayala, B. Monfils, W. G. Cioffi, and I. H. Chaudry. 1997. Mechanism of intestinal mucosal immune dysfunction following trauma-hemorrhage: increased apoptosis associated with elevated Fas expression in peyer's patches. J. Surg. Res. 70:55.
-
(1997)
J. Surg. Res.
, vol.70
, pp. 55
-
-
Xu, Y.X.1
Ayala, A.2
Monfils, B.3
Cioffi, W.G.4
Chaudry, I.H.5
-
7
-
-
0032770246
-
Apoptotic cell death in patients with sepsis, shock, and multiple organ dysfunction
-
Hotchkiss, R. S., P. E. Swanson, B. D. Freeman, K. W. Tinsley, J. P. Cobb, G. M. Matuschak, T. G. Buchman, and I. E. Karl. 1999. Apoptotic cell death in patients with sepsis, shock, and multiple organ dysfunction. Crit. Care Med. 27:1230.
-
(1999)
Crit. Care Med.
, vol.27
, pp. 1230
-
-
Hotchkiss, R.S.1
Swanson, P.E.2
Freeman, B.D.3
Tinsley, K.W.4
Cobb, J.P.5
Matuschak, G.M.6
Buchman, T.G.7
Karl, I.E.8
-
8
-
-
3643052918
-
Is Fas ligand or endotoxin responsible for mucosal lymphocyte apoptosis in sepsis?
-
Chung, C., X. X. Ying, W. Wang, I. H. Chaudry, and A. Ayala. 1998. Is Fas ligand or endotoxin responsible for mucosal lymphocyte apoptosis in sepsis? Arch. Surg. 133:1213.
-
(1998)
Arch. Surg.
, vol.133
, pp. 1213
-
-
Chung, C.1
Ying, X.X.2
Wang, W.3
Chaudry, I.H.4
Ayala, A.5
-
9
-
-
0033120115
-
Overexpression of BCL-2 in transgenic mice decreases apoptosis and improves survival in sepsis
-
Hotchkiss, R. S., P. E. Swanson, C. M. Knudson, K. C. Chang, J. P. Cobb, D. F. Osborne, K. M. Zollner, T. G. Buchman, S. J. Korsmeyer, and I. E. Karl. 1999. Overexpression of BCL-2 in transgenic mice decreases apoptosis and improves survival in sepsis. J. Immunol. 162:4148.
-
(1999)
J. Immunol.
, vol.162
, pp. 4148
-
-
Hotchkiss, R.S.1
Swanson, P.E.2
Knudson, C.M.3
Chang, K.C.4
Cobb, J.P.5
Osborne, D.F.6
Zollner, K.M.7
Buchman, T.G.8
Korsmeyer, S.J.9
Karl, I.E.10
-
10
-
-
0027477302
-
Aberrant transcription caused by the insertion of an early transposable element in an intron of the Fas antigen gene of lpr mice
-
Adachi, M., R. Watanabe-Fukunaga, and S. Nagata. 1993. Aberrant transcription caused by the insertion of an early transposable element in an intron of the Fas antigen gene of lpr mice. Proc. Natl. Acad. Sci. USA 90:1756.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 1756
-
-
Adachi, M.1
Watanabe-Fukunaga, R.2
Nagata, S.3
-
11
-
-
0028980902
-
Fas and Fas ligand: lpr and gld mutations
-
Nagata, S., and T. Suda. 1995. Fas and Fas ligand: lpr and gld mutations. Immunol. Today 16:39.
-
(1995)
Immunol. Today
, vol.16
, pp. 39
-
-
Nagata, S.1
Suda, T.2
-
12
-
-
0027319521
-
p53 is required for radiation-induced apoptosis in mouse thymocytes
-
Lowe, S. W., E. M. Schmitt, S. W. Smith, B. A. Osborne, and T. Jacks. 1993. p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 362:847.
-
(1993)
Nature
, vol.362
, pp. 847
-
-
Lowe, S.W.1
Schmitt, E.M.2
Smith, S.W.3
Osborne, B.A.4
Jacks, T.5
-
13
-
-
0030930366
-
A model for p53-induced apoptosis
-
Polyak, K., Y. Xia, J. L. Zweier, K. W. Kinzler, and B. Vogelstein. 1997. A model for p53-induced apoptosis. Nature 389:300.
-
(1997)
Nature
, vol.389
, pp. 300
-
-
Polyak, K.1
Xia, Y.2
Zweier, J.L.3
Kinzler, K.W.4
Vogelstein, B.5
-
14
-
-
0032500793
-
Cell surface trafficking of Fas: A rapid mechanism of p53-mediated apoptosis
-
Bennett, M., K. Macdonald, S. Chan, J. P. Luzio, R. Simari, and P. Weissberg. 1998. Cell surface trafficking of Fas: a rapid mechanism of p53-mediated apoptosis. Science 282:290.
-
(1998)
Science
, vol.282
, pp. 290
-
-
Bennett, M.1
Macdonald, K.2
Chan, S.3
Luzio, J.P.4
Simari, R.5
Weissberg, P.6
-
15
-
-
0031743648
-
p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs
-
Muller, M., S. Wilder, D. Bannasch, D. Israeli, K. Lehlbach, M. Li-Weber, S. L. Friedman, P. R. Galle, W. Stremmel, M. Oren, and P. H. Krammer. 1998. p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs. J. Exp. Med. 188:2033.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 2033
-
-
Muller, M.1
Wilder, S.2
Bannasch, D.3
Israeli, D.4
Lehlbach, K.5
Li-Weber, M.6
Friedman, S.L.7
Galle, P.R.8
Stremmel, W.9
Oren, M.10
Krammer, P.H.11
-
16
-
-
0020520054
-
Evaluation of factors affecting mortality rate after sepsis in a murine cecal ligation and puncture model
-
Baker, C. C., I. H. Chaudry, H. O. Gaines, and A. E. Baue. 1983. Evaluation of factors affecting mortality rate after sepsis in a murine cecal ligation and puncture model. Surgery 94:331.
-
(1983)
Surgery
, vol.94
, pp. 331
-
-
Baker, C.C.1
Chaudry, I.H.2
Gaines, H.O.3
Baue, A.E.4
-
17
-
-
0002449876
-
T cell maturation in the thymus
-
Saunders, Philadelphia
-
Abbas, A. K., A. H. Lichtman, and J. S. Pober. 1997. T cell maturation in the thymus. In Cellular and Molecular Immunology, 3rd Ed. Saunders, Philadelphia, p.174.
-
(1997)
Cellular and Molecular Immunology, 3rd Ed.
, pp. 174
-
-
Abbas, A.K.1
Lichtman, A.H.2
Pober, J.S.3
-
18
-
-
0031577506
-
Clues in the p53 murder mystery
-
Wylie, A. 1997. Clues in the p53 murder mystery. Nature 389:237.
-
(1997)
Nature
, vol.389
, pp. 237
-
-
Wylie, A.1
-
19
-
-
0029958381
-
Reactive oxygen species are downstream mediators of p53-dependent apoptosis
-
Johnson, T. M., V. J. Ferrans, R. A. Lowenstein, and T. Finkel. 1996. Reactive oxygen species are downstream mediators of p53-dependent apoptosis. Proc. Natl. Acad. Sci. USA 93:11848.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 11848
-
-
Johnson, T.M.1
Ferrans, V.J.2
Lowenstein, R.A.3
Finkel, T.4
-
20
-
-
0033946085
-
The role of CuZn superoxide dismutase in regulating lymphocyte apoptosis during sepsis
-
In press
-
Freeman, B. D., A. G. Reaume, P. E. Swanson, C. J. Epstein, E. J. Carlson, T. G. Buchman, I. E. Karl, and R. S. Hotchkiss. 1999 The role of CuZn superoxide dismutase in regulating lymphocyte apoptosis during sepsis. Crit. Care Med., In press.
-
(1999)
Crit. Care Med.
-
-
Freeman, B.D.1
Reaume, A.G.2
Swanson, P.E.3
Epstein, C.J.4
Carlson, E.J.5
Buchman, T.G.6
Karl, I.E.7
Hotchkiss, R.S.8
-
21
-
-
0031758328
-
p53, bax, and bcl-2 in vivo expression in the murine thymus after apoptogenic treatments
-
Denis, G., C. Humblet, M. Verlaet, J. Boniver, and M. P. Defresne. 1998. p53, bax, and bcl-2 in vivo expression in the murine thymus after apoptogenic treatments. Anticancer Res. 18:3315.
-
(1998)
Anticancer Res.
, vol.18
, pp. 3315
-
-
Denis, G.1
Humblet, C.2
Verlaet, M.3
Boniver, J.4
Defresne, M.P.5
-
22
-
-
0033086953
-
Does Fas ligand or endotoxin contribute to thymic apoptosis during polymicrobial sepsis?
-
Ayala, A., Y. X. Xu, C. S. Chung, and I. H. Chaudry. 1999. Does Fas ligand or endotoxin contribute to thymic apoptosis during polymicrobial sepsis? Shock 11:211.
-
(1999)
Shock
, vol.11
, pp. 211
-
-
Ayala, A.1
Xu, Y.X.2
Chung, C.S.3
Chaudry, I.H.4
-
23
-
-
0031110570
-
Cecal ligation and puncture (CLP) induces apoptosis in thymus, spleen, lung, and gut by an endotoxin and TNF-independent pathway
-
Hiramatsu, M., R. S. Hotchkiss, I. E. Karl, and T. G. Buchman. 1997. Cecal ligation and puncture (CLP) induces apoptosis in thymus, spleen, lung, and gut by an endotoxin and TNF-independent pathway. Shock 7:247.
-
(1997)
Shock
, vol.7
, pp. 247
-
-
Hiramatsu, M.1
Hotchkiss, R.S.2
Karl, I.E.3
Buchman, T.G.4
-
24
-
-
2642599034
-
Increased mucosal B-lymphocyte apoptosis during polymicrobial sepsis is a Fas ligand but not an endotoxin-mediated process
-
Ayala, A., Y. X. Xu, C. A. Ayala, D. E. Sonefeld, S. M. Karr, T. A. Evans, and I. H. Chaudry. 1998. Increased mucosal B-lymphocyte apoptosis during polymicrobial sepsis is a Fas ligand but not an endotoxin-mediated process. Blood 91: 1362.
-
(1998)
Blood
, vol.91
, pp. 1362
-
-
Ayala, A.1
Xu, Y.X.2
Ayala, C.A.3
Sonefeld, D.E.4
Karr, S.M.5
Evans, T.A.6
Chaudry, I.H.7
-
25
-
-
0032811068
-
Genetic models of abnormal apoptosis in lymphocytes
-
Refaeli, Y., L. V. Parijs, and A. K. Abbas. 1999. Genetic models of abnormal apoptosis in lymphocytes. Immunol. Rev. 169:273.
-
(1999)
Immunol. Rev.
, vol.169
, pp. 273
-
-
Refaeli, Y.1
Parijs, L.V.2
Abbas, A.K.3
-
26
-
-
0031948286
-
p53 in tumor progression: Life, death, and everything
-
Mowat, M. R. 1998. p53 in tumor progression: life, death, and everything. Adv. Cancer Res. 74:25.
-
(1998)
Adv. Cancer Res.
, vol.74
, pp. 25
-
-
Mowat, M.R.1
-
27
-
-
0032575688
-
The Bcl-2 protein family: Arbiters of cell survival
-
Adams, J. M., and S. Cory. 1998. The Bcl-2 protein family: arbiters of cell survival. Science 281:1322.
-
(1998)
Science
, vol.281
, pp. 1322
-
-
Adams, J.M.1
Cory, S.2
-
28
-
-
0033431682
-
Prevention of lymphocyte cell death in sepsis improves survival in mice
-
Hotchkiss, R. S., K. W. Tinsley, P. E. Swanson, K. C. Chang, J. P. Cobb, T. G. Buchman, S. J. Korsmeyer, and I. E. Karl. 1999. Prevention of lymphocyte cell death in sepsis improves survival in mice. Proc. Natl. Acad. Sci. USA 96: 14541.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 14541
-
-
Hotchkiss, R.S.1
Tinsley, K.W.2
Swanson, P.E.3
Chang, K.C.4
Cobb, J.P.5
Buchman, T.G.6
Korsmeyer, S.J.7
Karl, I.E.8
-
29
-
-
0033628936
-
Caspases -2,-3,-6, and -9, but not caspase-1, are activated in sepsis-induced thymocyte apoptosis
-
Tinsley, K. W., S. L. Cheng, T. G. Buchman, K. C. Chang, J. J. Hui, P. E. Swanson, I. E. Karl, and R. S. Hotchkiss. 2000. Caspases -2,-3,-6, and -9, but not caspase-1, are activated in sepsis-induced thymocyte apoptosis. Shock. 13:1.
-
(2000)
Shock
, vol.13
, pp. 1
-
-
Tinsley, K.W.1
Cheng, S.L.2
Buchman, T.G.3
Chang, K.C.4
Hui, J.J.5
Swanson, P.E.6
Karl, I.E.7
Hotchkiss, R.S.8
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