메뉴 건너뛰기




Volumn 19, Issue 6, 2001, Pages 217-222

Proteomics: A technology-driven and technology-limited discovery science

Author keywords

[No Author keywords available]

Indexed keywords

DNA SEQUENCES; ELECTROPHORESIS; GENES; MASS SPECTROMETRY; METABOLITES; PROTEINS; RNA;

EID: 0035371837     PISSN: 01677799     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0167-7799(01)01639-0     Document Type: Article
Times cited : (101)

References (42)
  • 1
    • 0034659898 scopus 로고    scopus 로고
    • Genomics, gene expression and DNA arrays
    • Lockhart, D. and Winzeler, E. (2000) Genomics, gene expression and DNA arrays. Nature 405, 827-836
    • (2000) Nature , vol.405 , pp. 827-836
    • Lockhart, D.1    Winzeler, E.2
  • 2
    • 0033664358 scopus 로고    scopus 로고
    • RNA expression analysis using a 30 base pair resolution Escherichia coli genome array
    • Selinger, D. et al. (2000) RNA expression analysis using a 30 base pair resolution Escherichia coli genome array Nat. Biotechnol. 18, 1262-1268
    • (2000) Nat. Biotechnol. , vol.18 , pp. 1262-1268
    • Selinger, D.1
  • 3
    • 0030895921 scopus 로고    scopus 로고
    • A comparison of selected mRNA and protein abundances in human liver
    • Anderson, L. and Seilhamer, J. (1997) A comparison of selected mRNA and protein abundances in human liver. Electrophoresis 18, 533-537
    • (1997) Electrophoresis , vol.18 , pp. 533-537
    • Anderson, L.1    Seilhamer, J.2
  • 4
    • 0033016717 scopus 로고    scopus 로고
    • Correlation between protein and mRNA abundance in yeast
    • Gygi, S.P. et al. (1999) Correlation between protein and mRNA abundance in yeast. Mol. Cell. Biol. 19, 1720-1730
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 1720-1730
    • Gygi, S.P.1
  • 5
    • 0033206211 scopus 로고    scopus 로고
    • Dynamical analysis of gene networks requires both mRNA and protein expression information
    • Hatzimanikatis, V. and Lee, K.H. (1999) Dynamical analysis of gene networks requires both mRNA and protein expression information. Metabolic Eng. 1, 275-281
    • (1999) Metabolic Eng. , vol.1 , pp. 275-281
    • Hatzimanikatis, V.1    Lee, K.H.2
  • 6
    • 0029033175 scopus 로고
    • Progress with gene-product mapping of the Mollicutes: Mycoplasma genitalium
    • Wasinger, V. et al. (1995) Progress with gene-product mapping of the Mollicutes: Mycoplasma genitalium. Electrophoresis 16, 1090-1094
    • (1995) Electrophoresis , vol.16 , pp. 1090-1094
    • Wasinger, V.1
  • 7
    • 0016711037 scopus 로고
    • High resolution two-dimensional electrophoresis of proteins
    • O'Farrell, P. (1975) High resolution two-dimensional electrophoresis of proteins. J. Biol. Chem. 250, 4007-4021
    • (1975) J. Biol. Chem. , vol.250 , pp. 4007-4021
    • O'Farrell, P.1
  • 8
    • 0034076276 scopus 로고    scopus 로고
    • A comparison of three commercially available isoelectric focusing units for proteome analysis: The Multiphor, the IPGphor and the Protean IEF Cell
    • Choe, L.H. and Lee, K.H. (2000) A comparison of three commercially available isoelectric focusing units for proteome analysis: the Multiphor, the IPGphor and the Protean IEF Cell. Electrophoresis 21, 993-1000
    • (2000) Electrophoresis , vol.21 , pp. 993-1000
    • Choe, L.H.1    Lee, K.H.2
  • 9
    • 0027763435 scopus 로고
    • A nonlinear wide-range immobilized pH gradient for two-dimensional electrophoresis and its definition in a relevant pH scale
    • Bjellqvist, B. et al. (1993) A nonlinear wide-range immobilized pH gradient for two-dimensional electrophoresis and its definition in a relevant pH scale. Electrophoresis 14, 1357-1365
    • (1993) Electrophoresis , vol.14 , pp. 1357-1365
    • Bjellqvist, B.1
  • 10
    • 0033672478 scopus 로고    scopus 로고
    • A turning point in proteome analysis: Sample prefractionation via multicompartment electrolyzers with isoelectric membranes
    • Herbert, B. and Righetti, P.G. (2000) A turning point in proteome analysis: sample prefractionation via multicompartment electrolyzers with isoelectric membranes. Electrophoresis 21, 3639-3648
    • (2000) Electrophoresis , vol.21 , pp. 3639-3648
    • Herbert, B.1    Righetti, P.G.2
  • 11
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, U.K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 12
    • 0018648853 scopus 로고
    • Trace polypeptides in cellular extracts and human body fluids detected by two-dimensional electrophoresis and a highly sensitive silver stain
    • Merrill, C.M. et al. (1979) Trace polypeptides in cellular extracts and human body fluids detected by two-dimensional electrophoresis and a highly sensitive silver stain. Proc. Natl. Acad. Sci. U.S.A. 76, 4335-4339
    • (1979) Proc. Natl. Acad. Sci. U.S.A. , vol.76 , pp. 4335-4339
    • Merrill, C.M.1
  • 13
    • 0034075850 scopus 로고    scopus 로고
    • Making blind robots see: The synergy between fluorescent dyes and imaging devices in automated proteomics
    • Patton, W.F. (2000) Making blind robots see: the synergy between fluorescent dyes and imaging devices in automated proteomics. BioTechniques 28, 944-957
    • (2000) BioTechniques , vol.28 , pp. 944-957
    • Patton, W.F.1
  • 14
    • 0032694167 scopus 로고    scopus 로고
    • A sampling of the yeast proteome
    • Futcher, B. et al. (1999) A sampling of the yeast proteome. Mol. Cell. Biol. 19, 7357-7368
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 7357-7368
    • Futcher, B.1
  • 15
    • 0034097324 scopus 로고    scopus 로고
    • Proteomics: Capacity versus utility
    • Harry, J.L. et al. (2000) Proteomics: capacity versus utility. Electrophoresis 21, 1071-1081
    • (2000) Electrophoresis , vol.21 , pp. 1071-1081
    • Harry, J.L.1
  • 16
    • 0034662907 scopus 로고    scopus 로고
    • Evaluation of two-dimensional gel electrophoresis-based proteome analysis technology
    • Gygi, S.P. et al. (2000) Evaluation of two-dimensional gel electrophoresis-based proteome analysis technology. Proc. Natl. Acad. Sci. U. S. A. 17, 9390-9395
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.17 , pp. 9390-9395
    • Gygi, S.P.1
  • 17
    • 0023430927 scopus 로고
    • Internal amino acid sequence analysis of proteins separated by one- Or two-dimensional gel electrophoresis
    • Aebersold, R.H. et al. (1987) Internal amino acid sequence analysis of proteins separated by one- or two-dimensional gel electrophoresis. Proc. Natl. Acad. Sci. U. S. A. 84, 6970-6974
    • (1987) Proc. Natl. Acad. Sci. U. S. A. , vol.84 , pp. 6970-6974
    • Aebersold, R.H.1
  • 18
    • 0033918391 scopus 로고    scopus 로고
    • Mass spectrometry: A tool for the identification of proteins separated by gels
    • Lahm, H. and Langen, H. (2000) Mass spectrometry: a tool for the identification of proteins separated by gels. Electrophoresis 21, 2105-2114
    • (2000) Electrophoresis , vol.21 , pp. 2105-2114
    • Lahm, H.1    Langen, H.2
  • 19
    • 0033904796 scopus 로고    scopus 로고
    • Proteomics: The industrialization of protein chemistry
    • Patterson, S.D. (2000) Proteomics: the industrialization of protein chemistry. Curr. Opin. Biotechnol. 11, 413-418
    • (2000) Curr. Opin. Biotechnol. , vol.11 , pp. 413-418
    • Patterson, S.D.1
  • 20
    • 0343674504 scopus 로고    scopus 로고
    • Protein arrays for gene expression and molecular interaction screening
    • Walter, G. et al. (2000) Protein arrays for gene expression and molecular interaction screening. Curr. Opin. Microbiol. 3, 298-302
    • (2000) Curr. Opin. Microbiol. , vol.3 , pp. 298-302
    • Walter, G.1
  • 21
    • 0034425742 scopus 로고    scopus 로고
    • Antibody arrays for high-throughput screening of antibody-antigen interactions
    • De Wildt, R.M.T. et al. (2000) Antibody arrays for high-throughput screening of antibody-antigen interactions. Nat. Biotechnol. 18, 989-994
    • (2000) Nat. Biotechnol. , vol.18 , pp. 989-994
    • De Wildt, R.M.T.1
  • 22
    • 0033562573 scopus 로고    scopus 로고
    • Protein microarrays for gene expression and antibody screening
    • Lueking, A. et al. (1999) Protein microarrays for gene expression and antibody screening. Anal. Biochem. 270, 103-111
    • (1999) Anal. Biochem. , vol.270 , pp. 103-111
    • Lueking, A.1
  • 23
    • 0002118614 scopus 로고    scopus 로고
    • Protein microarrays for highly parallel detection and quantitation of specific proteins and antibodies in complex solutions
    • Haab, B.B. et al. (2000) Protein microarrays for highly parallel detection and quantitation of specific proteins and antibodies in complex solutions. Genome Biology 1, 0004.1-0004.13.
    • (2000) Genome Biology , vol.1
    • Haab, B.B.1
  • 24
    • 0034622925 scopus 로고    scopus 로고
    • Printing proteins as microarrays for high-throughput function determination
    • MacBeath, G. and Schreiber, S.L. (2000) Printing proteins as microarrays for high-throughput function determination. Science 289, 1760-1763
    • (2000) Science , vol.289 , pp. 1760-1763
    • MacBeath, G.1    Schreiber, S.L.2
  • 25
    • 0033175822 scopus 로고    scopus 로고
    • Fingerprinting disease with protein chip arrays
    • Senior, K. (1999) Fingerprinting disease with protein chip arrays. Mol. Med. Today 5, 326-327
    • (1999) Mol. Med. Today , vol.5 , pp. 326-327
    • Senior, K.1
  • 26
    • 0034013944 scopus 로고    scopus 로고
    • Recent advances in surface-enhanced laser desorption/ionization-time of flight mass spectrometry
    • Merchant, M. and Weinberger, S.R. (2000) Recent advances in surface-enhanced laser desorption/ionization-time of flight mass spectrometry. Electrophoresis 21, 1164-1177
    • (2000) Electrophoresis , vol.21 , pp. 1164-1177
    • Merchant, M.1    Weinberger, S.R.2
  • 27
    • 0034042053 scopus 로고    scopus 로고
    • Generation of a baculovirus recombinant prostate-specific membrane antigen and its use in the development of a novel protein biochip quantitative immunoassay
    • Xiao, Z. et al. (2000) Generation of a baculovirus recombinant prostate-specific membrane antigen and its use in the development of a novel protein biochip quantitative immunoassay. Protein Expres. Purif. 19, 12-21
    • (2000) Protein Expres. Purif. , vol.19 , pp. 12-21
    • Xiao, Z.1
  • 28
    • 0034063779 scopus 로고    scopus 로고
    • Rapid protein display profiling of cancer progression directly from human tissue using a protein biochip
    • Paweletz, C.P. et al. (2000) Rapid protein display profiling of cancer progression directly from human tissue using a protein biochip. Drug Dev. Res. 49, 34-42
    • (2000) Drug Dev. Res. , vol.49 , pp. 34-42
    • Paweletz, C.P.1
  • 29
    • 0034012952 scopus 로고    scopus 로고
    • Biosensor chip mass spectrometry: A chip-based proteomics approach
    • Nelson, R.W. et al. (2000) Biosensor chip mass spectrometry: a chip-based proteomics approach. Electrophoresis 21, 1155-1163
    • (2000) Electrophoresis , vol.21 , pp. 1155-1163
    • Nelson, R.W.1
  • 30
    • 0033987862 scopus 로고    scopus 로고
    • An enhanced microfluidic chip coupled to an electrospray Qstar mass spectrometer for protein identification
    • Pinto, D. et al. (2000) An enhanced microfluidic chip coupled to an electrospray Qstar mass spectrometer for protein identification. Electrophoresis 21, 181-190
    • (2000) Electrophoresis , vol.21 , pp. 181-190
    • Pinto, D.1
  • 31
    • 0034307403 scopus 로고    scopus 로고
    • Electrophoretic separation of proteins on a microchip with noncovalent, postcolumn labeling
    • Liu, Y. et al. (2000) Electrophoretic separation of proteins on a microchip with noncovalent, postcolumn labeling. Anal. Chem. 72, 4608-4613
    • (2000) Anal. Chem. , vol.72 , pp. 4608-4613
    • Liu, Y.1
  • 32
    • 0034604760 scopus 로고    scopus 로고
    • Integrated microchip-device for the digestion, separation and postcolumn labeling of proteins and peptides
    • Gottschlich, N. et al. (2000) Integrated microchip-device for the digestion, separation and postcolumn labeling of proteins and peptides. J. Chromatogr. B 745, 243-249
    • (2000) J. Chromatogr. B , vol.745 , pp. 243-249
    • Gottschlich, N.1
  • 33
    • 0034282965 scopus 로고    scopus 로고
    • Nanoliter liquid metering in microchannels using hydrophobic patterns
    • Handique, K. et al. (2000) Nanoliter liquid metering in microchannels using hydrophobic patterns. Anal. Chem. 72, 4100-4109
    • (2000) Anal. Chem. , vol.72 , pp. 4100-4109
    • Handique, K.1
  • 34
    • 0033868723 scopus 로고    scopus 로고
    • Integration of immobilized trypsin bead beds for protein digestion within a microfluidic chip incorporating capillary electrophoresis separations and an electrospray mass spectrometry interface
    • Wang, C. et al. (2000) Integration of immobilized trypsin bead beds for protein digestion within a microfluidic chip incorporating capillary electrophoresis separations and an electrospray mass spectrometry interface. Rapid Commun. Mass Spectrom. 14, 1377-1383
    • (2000) Rapid Commun. Mass Spectrom. , vol.14 , pp. 1377-1383
    • Wang, C.1
  • 35
    • 0033964118 scopus 로고    scopus 로고
    • High-throughput and ultra-high-throughput screening: Solution- And cell-based approaches
    • Sundberg, S.A. (2000) High-throughput and ultra-high-throughput screening: solution- and cell-based approaches. Curr. Opin. Biotech. 11, 47-53
    • (2000) Curr. Opin. Biotech. , vol.11 , pp. 47-53
    • Sundberg, S.A.1
  • 36
    • 0032875697 scopus 로고    scopus 로고
    • Quantitative analysis of complex protein mixtures using isotope-coded affinity tags
    • Gygi, S.P. et al. (1999) Quantitative analysis of complex protein mixtures using isotope-coded affinity tags. Nat. Biotechnol. 17, 994-998
    • (1999) Nat. Biotechnol. , vol.17 , pp. 994-998
    • Gygi, S.P.1
  • 37
    • 0033230904 scopus 로고    scopus 로고
    • Toward a clinical molecular scanner for proteome research: Parallel protein chemical processing before and during Western blot
    • Bienvenut, W.V. et al. (1999) Toward a clinical molecular scanner for proteome research: parallel protein chemical processing before and during Western blot. Anal. Chem. 71, 4800-4807
    • (1999) Anal. Chem. , vol.71 , pp. 4800-4807
    • Bienvenut, W.V.1
  • 38
    • 0041939641 scopus 로고    scopus 로고
    • A molecular scanner to automate proteomics research and to display proteome images
    • Binz, P. et al. (1999) A molecular scanner to automate proteomics research and to display proteome images. Anal. Chem. 71, 4981-4988
    • (1999) Anal. Chem. , vol.71 , pp. 4981-4988
    • Binz, P.1
  • 39
    • 0034659815 scopus 로고    scopus 로고
    • Proteomics to study genes and genomes
    • Pandey, A. and Mann, M. (2000) Proteomics to study genes and genomes. Nature 405, 837-846
    • (2000) Nature , vol.405 , pp. 837-846
    • Pandey, A.1    Mann, M.2
  • 41
    • 0033919787 scopus 로고    scopus 로고
    • Proteomics: Applications and opportunities in preclinical drug development
    • Steiner, S. and Witzmann, F.A. (2000) Proteomics: applications and opportunities in preclinical drug development Electrophoresis 21, 2099-2104
    • (2000) Electrophoresis , vol.21 , pp. 2099-2104
    • Steiner, S.1    Witzmann, F.A.2
  • 42
    • 0031092897 scopus 로고    scopus 로고
    • The coming Kuhnian revolution in biology
    • Strohman, R.C. (1997) The coming Kuhnian revolution in biology. Nat. Biotechnol. 15, 194-200
    • (1997) Nat. Biotechnol. , vol.15 , pp. 194-200
    • Strohman, R.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.