Theoretical evidence of a salt bridge disruption as the initiating process for the α1d-adrenergic receptor activation: A molecular dynamics and docking study

Proteins: Structure, Function and Genetics

Volumn 43, Issue 4, 2001, Pages 382-394

  Carrieri, A ^a   Centeno, N B ^b   Rodrigo, J ^b   Sanz, F ^b   Carotti, A ^a  

^a UNIVERSITY OF BARI   (Italy)

^b UNIVERSITAT POMPEU FABRA   (Spain)

Author keywords

Conformational analysis; Discretamine; G protein coupled receptors; Molecular modeling; Noradrenaline

Indexed keywords

ALPHA 1D ADRENERGIC RECEPTOR; DISCRETAMINE; G PROTEIN COUPLED RECEPTOR; NORADRENALIN; RHODOPSIN;

ARTICLE; BINDING SITE; CRYOELECTRON MICROSCOPY; MOLECULAR DYNAMICS; MOLECULAR MODEL; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STRUCTURE; RAT; RECEPTOR BINDING; RECEPTOR INTRINSIC ACTIVITY; STRUCTURE ANALYSIS; THREE DIMENSIONAL IMAGING;

AMINO ACID SEQUENCE; ANIMALS; BERBERINE ALKALOIDS; BINDING SITES; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NOREPINEPHRINE; PROTEIN BINDING; PROTEIN CONFORMATION; RATS; RECEPTORS, ADRENERGIC, ALPHA-1; RECEPTORS, CELL SURFACE; RECEPTORS, G-PROTEIN-COUPLED; SACCHAROMYCES CEREVISIAE PROTEINS; SALTS; SOLUBILITY;

EID: 0035371114     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/prot.1051     Document Type: Article

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