Phenylalanine in the second membrane-spanning domain of α(1A)- adrenergic receptor determines subtype selectivity of dihydropyridine antagonists

Biochemistry

Volumn 35, Issue 45, 1996, Pages 14312-14317

  Hamaguchi, Nobuko ^a   True, Timothy A ^a   Saussy Jr , David L ^a   Jeffs, Peter W ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; DIHYDROPYRIDINE; PHENYLALANINE; RECEPTOR SUBTYPE;

ADRENERGIC SYSTEM; AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; CARDIOVASCULAR DISEASE; DRUG RECEPTOR BINDING; HUMAN; LIGAND BINDING; PRIORITY JOURNAL; SEQUENCE HOMOLOGY;

ADRENERGIC ALPHA-ANTAGONISTS; AMINO ACID SEQUENCE; ANIMALS; COS CELLS; HUMANS; MEMBRANE GLYCOPROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PHENYLALANINE; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, ADRENERGIC, ALPHA; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0029807131     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi961024e     Document Type: Article

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