Chromosomal instability and its relationship to other end points of genomic instability

Cancer Research

Volumn 57, Issue 24, 1997, Pages 5557-5563

  Limoli, Charles L ^a   Kaplan, Mark I ^a,b   Corcoran, James ^a   Meyers, Mark ^d   Boothman, David A ^d   Morgan, William F ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^d UNIVERSITY OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CELL DEATH; CHROMOSOME ABERRATION; CONTROLLED STUDY; DNA DAMAGE; GENE AMPLIFICATION; GENETIC STABILITY; HUMAN CELL; MOLECULAR CLONING; MUTATION; NONHUMAN; PRIORITY JOURNAL; RADIATION EXPOSURE; RADIATION INJURY; X RAY;

NON-PROGRAMMATIC;

ANIMALS; CELL DEATH; CHO CELLS; CHROMOSOME ABERRATIONS; CHROMOSOMES, HUMAN, PAIR 4; CRICETINAE; DNA REPAIR; GENE AMPLIFICATION; GENOME; HUMANS; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MUTATION; PHENOTYPE; SISTER CHROMATID EXCHANGE; X-RAYS;

EID: 0031457070     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (52)

1. Morgan, W. F., Day, J. P., Kaplan, M. I., McGhee, E. M., and Limoli, C. L. Genomic instability induced by ionizing radiation. Radiat. Res., 146: 247-258, 1996.
2. Nowell, P. C. The clonal evolution of tumor cell populations. Science (Washington DC), 194: 23-28, 1976.
3. Loeb, L. A. Mutator phenotype may be required for multistage carcinogenesis. Cancer Res., 51: 3075-3079, 1991.
4. Kadhim, M. A., MacDonald, D. A., Goodhead, D. T., Lorimore, S. A., Marsden, S. J., and Wright, E. G. Transmission of chromosomal instability after plutonium alphaparticle irradiation. Nature (Lond.), 355: 738-740, 1992.
5. Holmberg, K., Fait, S., Johansson, A., and Lambert, B. Clonal chromosome aberrations and genomic instability in X-irradiated human T-lymphocyte cultures. Mutat. Res., 286: 321-330, 1993.
6. Martins, M. B., Sabatier, L., Ricoul, M., Pinton, A., and Dutrillaux, B. Specific chromosome instability induced by heavy ions: a step towards transformation of human fibroblasts? Mutat. Res., 285: 229-237, 1993.
7. Marder, B. A., and Morgan, W. F. Delayed chromosomal instability induced by DNA damage. Mol. Cell. Biol., 13: 6667-6677, 1993.
8. Kadhim, M. A., Lorimore, S. A., Hepburn, M. D., Goodhead, D. T., Buckle, V. J., and Wright, E. G. α-Particle-induced chromosomal instability in human bone marrow cells. Lancet, 344: 987-988, 1994.
9. Sabatier, L., Lebeau, J., and Dutrillaux, B. Chromosomal instability and alterations of telomeric repeats in irradiated human fibroblasts. Int. J. Radiat. Biol., 66: 611-613, 1994.
10. Mitelman, F. Catalog of Chromosome Aberrations in Cancer, Ed. 4. New York: Wiley-Liss, 1991.
11. Loeb, L. A. Microsatellite instability: marker of a mutator phenotype in cancer. Cancer Res., 54: 5059-5063, 1994.
12. Morgan, W. F., and Murnane, J. P. A role for genomic instability in cellular radioresistance? Cancer Metastasis Rev., 14: 49-58, 1995.
13. Chang, W. P., and Little, J. B. Persistently elevated frequency of spontaneous mutations in progeny of CHO clones surviving X-irradiation: association with delayed reproductive death phenotype. Mutat. Res., 270: 191-199, 1992.
14. Fishel, R., Lescoe, M. K., Rao, M. R. S., Copeland, N. G., Jenkins, N. A., Garber, J., Kane, M., and Kolodner, R. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer [published erratum appears in Cell, 77: 167, 1994]. Cell, 75: 1027-1038, 1993.
15. Leach, F. S., Nicolaides, N. C., Papadopoulos, N., Liu, B., Jen, J., Parsons, R., Peltomaki, P., Sistonen, P., Aaltonen, L. A., Nystrom-Lahti, M., Guan, X-Y., Zhang, J., Meltzer, P. S., Yu, J-W., Kao, F-T., Chen, D. J., Cerosaletti, K. M., Fournier, R. E. K., Todd, S., Lewis, T., Leach, R. J., Naylor, S. L., Weissenbach, J., Mecklin, J-P., Jarvinen, H., Petersen, G. M., Hamilton, S. R., Green, J., Jass, J., Watson, P., Lynch, H. T., Trent, J. M., de la Chapelle, A., Kinzler, K, W., and Vogelstein, B. Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer. Cell, 75: 1215-1225, 1993.
16. Ionov, Y., Peinado, M. A., Malkhosyan, S., Shibata, D., and Perucho, M. Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonie carcinogenesis. Nature (Lond.), 363: 558-561, 1993.
17. Peltomaki, P., Lothe, R. A., Aaltonen, L. A., Pylkkanen, L., Nystrom-Lahti, M., Seruca, R., David, L., Holm, R., Ryberg, D., Haugen, A,. Brogger, A., Borresen, A-L., and de la Chapelle, A. Microsatellite instability is associated with tumors that characterize the hereditary non-polyposis colorectal carcinoma syndrome. Cancer Res., 53: 5853-5855, 1993.
18. Papadopoulos, N., Nicolaides, N. C., Wei, Y-F., Ruben, S. M., Carter, K. C., Rosen, C. A., Haseltine, W. A., Fleischmann, R. D., Fraser, C. M., Adams, M. D., Venter, J. C., Hamilton, S. R., Petersen, G. M., Watson, P., Lynch, H. T., Peltomaki, P., Mecklin, J-P., de la Chapelle, A., Kinzler, K. W., and Vogelstein, B. Mutation of a mutL homolog in hereditary colon cancer. Science (Washington DC), 263: 1625-1629, 1994.
19. Little, J. B. Changing views of cellular radiosensitivity. Radiat. Res., 140: 299-311, 1994.
20. de Wind, N., Dekker, M., Berns, A., Radman, M., and te Riele, H. Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer. Cell, 82: 321-330, 1995.
21. Hendry, J. H., and West, C. M. Implications of delayed reproductive cell death (lethal mutations/genomic instability) for the interpretation of tissue responses. Int. J. Radiat. Biol., 68: 363-367, 1995.
22. Chang, W. P., and Little, J. B. Delayed reproductive death in X-irradiated Chinese hamster ovary cells. Int. J. Radiat. Biol., 60: 483-496, 1991.
23. Chang, W. P., and Little, J. B. Evidence that DNA double-strand breaks initiate the phenotype of delayed reproductive death in Chinese hamster ovary cells. Radiat. Res., 131: 53-59, 1992.
24. Chang, W. P., and Little, J. B. Delayed reproductive death as a dominant phenotype in cell clones surviving X-irradiation. Carcinogenesis (Lond.), 13: 923-928, 1992.
25. Cheng, K. C., and Loeb, L. A. Genomic instability and tumor progression: mechanistic considerations. Adv. Cancer Res., 60: 121-156, 1993.
26. Mendonca, M. S., Antoniono, R. J., and Redpath, J. L. Delayed heritable damage and epigenetics in radiation-induced neoplastic transformation of human hybrid cells. Radiat. Res., 134: 209-216, 1993.
27. Mendonca, M. S., Fasching, C. L., Srivatsan, E. S., Stanbridge, E. J., and Redpath, J. L. Loss of a putative tumor suppressor locus after gamma-ray-induced neoplastic transformation of HeLa X skin fibroblast human cell hybrids. Radiat. Res., 143: 34-44, 1995.
28. Tucker, J. D., Morgan, W. F., Awa, A. A., Bauchinger, M., Blakey, D., Cornforth, M. N., Littlefield, L. G., Natarajan, A. T., and Shasserre, C. A proposed system for scoring structural aberrations detected by chromosome painting. Cytogenet. Cell Genet., 68: 211-221, 1995.
29. Schaefer, D. I. Livanos, E. M., White, A. E., and Tlsty, T. D. Multiple mechanisms of N-(phosphonacetyl)-L-aspartate drug resistance in SV4Q-infected precrisis human fibroblasts. Cancer Res., 53: 4946-4951, 1993.
30. Morgan, W. F., Schwartz, J. L., Murnane, J. P., and Wolff, S. Effect of 3-aminobenzamide on sister chromatid exchange frequency in X-irradiated cells. Radiat. Res., 93: 567-571, 1983.
31. Morgan, W. F., Fero, M. L., Land, M. C., and Winegar, R. A. Inducible expression and cytogenetic effects of the EcoRI restriction endonuclease in Chinese hamster ovary cells. Mol. Cell. Biol., 8: 4204-4211, 1988.
32. Perry, P., and Wolff, S. New Geimsa method tor the differential staining of sister chromatids. Nature (Lond.), 251: 156-158, 1974.
33. Jiricny, J., Hughes, M., Corman, N., and Rudkin, B. B. A human 200-kDa protein binds selectively to DNA fragments containing GT mismatches. Proc. Natl. Acad. Sci. USA, 85: 8860-8864, 1988.
34. Luke, W., Hoefer, K., Moosmayer, D., Nickel, P., Hunsmann, G., and Jentsch, K-D. Partial purification and characterization of the reverse transcriptase of the simian immunodeficiency virus TYO-7 isolated from an African green monkey. Biochemistry, 29: 1764-1769, 1990.
35. Bradford, M. M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem., 72: 248-254, 1976.
36. Stephenson, C., and Karran, P. Selective binding to DNA base pair mismatches by proteins from human cells. J. Biol. Chem., 264: 21177-21182, 1989.
37. Meyers, M., Theodosiou, M., Acharya, S., Odegaard, E., Wilson, T., Lewis, J. E., Davis, T. W., Wilson-Van Patten, C. Fishel, R., and Boothman, D. A. Cell cycle regulation of the human DNA mismatch repair genes hMSH2, hMLH1, and hPMS2. Cancer Res., 57: 206-208, 1997.
38. Glantz, S. A. Primer of Biostatistics, pp. 88-89. New York: McGraw-Hill, 1987.
39. Aquilina, G., Hess, P., Branch, P., MacGeoch, C., Casciano, L, Karran, P., and Bignami, M. A mismatch recognition defect in colon carcinoma confers DNA microsatellite instability and a mutator phenotype. Proc. Natl. Acad. Sci. USA, 91: 8905-8909, 1994.
40. Alvarez, L., Evans, J. W., Wilks, R., Lucas, J. N., Brown, J. M., and Giaccia, A. J. Chromosomal radiosensitivity at intrachromosomal telomeric sites. Genes Chromosomes Cancer, 8: 8-14, 1993.
41. Ashley, T., Cacheiro, N. L. A., Russell, L. B., and Ward, D. C. Molecular characterization of a pericemric inversion in mouse chromosome 8 implicates telomeres as promoters of meiotic recombination. Chromosoma, 102: 112-120, 1993.
42. Ashley, T., and Ward, D. C. A. "Hot spot" of recombination coincides with an interstitial telomeric sequence in the Armenian hamster. Cytogenet. Cell Genet., 62: 169-171, 1993.
43. Day, J. P., Marder, B. A., and Morgan, W. F. Telomeres and their possible role in chromosome stabilization. Environ. Mol. Mutagen., 22: 245-249, 1993.
44. Seymour, C. B., Mothersill, C., and Alper, T. High yields of lethal mutations in somatic mammalian cells that survive ionizing radiation. Int. J. Radiat. Biol., 50: 167-179, 1986.
45. Mothersill, C., and Seymour, C. The influence of lethal mutations on the quantification of radiation transformation frequencies. Int. J. Radiat. Biol., 51: 723-729, 1987.
46. Hahn, P., Morgan, W. F., and Painter, R. B. The role of acentric chromosome fragments in gene amplification. Somat. Cell Mol. Genet., 13: 597-608, 1987.
47. Ruiz, J. C., and Wahl, G. M. Chromosomal destabilization during gene amplification. Mol. Cell. Biol., 10: 3056-3066, 1990.
48. Windle, B., Draper, B. W., Yin, Y. X., O'Gorman, S., and Wahl, G. M. A cenlral role for chromosome breakage in gene amplification, deletion formation, and amplicon integration. Genes Dev., 5: 160-174, 1991.
49. Poupon, M-F., Smith, K. A., Chernova, O. B., Gilbert, C., and Stark, G. R. Inefficient growth arrest in response to dNTP starvation stimulates gene amplification through bridge-breakage-fusion cycles. Mol. Biol. Cell., 7: 345-354, 1996.
50. Sancar, A., and Hearst, J. E. Molecular matchmakers. Science (Washington DC), 259: 1415-1420, 1993.
51. Karran, P., and Bignami, M. DNA damage tolerance, mismatch repair and genome instability. BioEssays, 16: 833-839, 1994.
52. Modrich, P. Mismatch repair, genetic stability, and cancer. Science (Washington DC), 266: 1959-1960, 1994.