Three distinct roles for TGF-beta during intercellular induction of apoptosis: A review

Anticancer Research

Volumn 19, Issue 1 A, 1999, Pages 105-111

  Häufel, Thomas ^a   Dormann, Sabine ^a   Hanusch, Jörg ^a   Schwieger, Agnes ^a   Bauer, Georg ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Apoptosis survival factor; TGF beta

Indexed keywords

FIBROBLAST GROWTH FACTOR; TRANSFORMING GROWTH FACTOR BETA;

APOPTOSIS; ARTICLE; CELL SURVIVAL; CELL TRANSFORMATION; FIBROBLAST; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN SECRETION; TUMOR CELL;

ANIMALS; APOPTOSIS; CELL TRANSFORMATION, NEOPLASTIC; HUMANS; REACTIVE OXYGEN SPECIES; TRANSFORMING GROWTH FACTOR BETA;

EID: 0344507146     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (61)

1. Roberts AB, Anzano MA, Lamb LC, Smith JM and Sporn MB: New class of transforming growth factors potentiated by epidermal growth factor: isolation from non-neoplastic tissues. Proc Natl Acad Sci USA 78: 5339-5343, 1981.
2. Bauer G, Höfler P and zur Hausen H: Epstein-Barr virus induction by a serum factor. I. Induction and cooperation with additional inducers. Virology 121: 184-194, 1982.
3. Bauer G, Hofler P and Simon M: Epstein-Barr virus induction by a serum factor. II. Purification of a high molecular weight protein that is responsible for induction. J Biol Chem 257: 11405-11410, 1982.
4. Bauer G, Höfler P and Simon M: Epstein-Barr virus induction by a serum factor. III. Characterization of the purified molecule and the mechanism of its activation. J Biol Chem 257: 11411-11415, 1982.
5. Roberts AB, Anzano MA, Wakefield LM, Roche NS, Stern DF and Sporn MB: Type β transforming growth factor: a bifunctional regulator of cell growth. Proc Natl Acad Sci USA 82: 119-123, 1985.
6. Barnard JA, Lyons RM and Moses HL: The cell biology of transforming growth factor beta. Biochim Biophys Acta 1032: 79-87, 1990.
7. Massagué J: The transforming growth factor-beta family. Annu Rev Cell Biol 6: 597-641, 1990.
8. Roberts AB and Sporn MB: The transforming growth factor-betas. In: Peptide Growth Factors and Their Receptors. Sporn MB and Roberts AB, eds. (Heidelberg: Springer-Verlag), 1990.
9. Gressner AM, Lahme B, Mannherz HG and Polzar B: TGF-beta-mediated hepatocellular apoptosis by rat and human hepatoma cells and primary rat hepatocytes. J Hepatology 26: 1079-1092, 1997.
10. Inayat Hussain SH, Couet C, Cohen GM and Cain K: Processing/ activation of CPP32-like proteases is involved in transforming growth factor beta-1-induced apoptosis in rat hepatocytes. Hepatology 25: 1516-1526, 1997.
11. Mullauer L, Grasl Kraupp B, Bursch W, and Schulte Hermann R: Transforming growth factor beta-1-induced cell death in preneoplastic foci of rat liver and sensitization by the antiestrogen tamoxifen. Hepatology 23: 840-847, 1996.
12. Oberhammer FA, Pavelka M, Sharma S, Tiefenbacher R, Purchio AF, Bursch W and Schulte Hermann R: Induction of apoptosis in cultured hepatocytes and in regressing liver by transforming growth factor beta-1. Proc Natl Acad Sci USA 89: 5408-5412, 1992.
13. Sanchez A, Alvarez AM, Benito M and Fabregat I: Apoptosis induced by transforming growth factor-beta in fetal hepatocyte primary cultures: Involvement of reactive oxygen intermediates. J Biol Chem 271: 7416-7422, 1996.
14. Antoshina E and Ostrowski LE: TGF-beta-1 induces growth arrest and apoptosis but not ciliated cell differentiation in rat tracheal epithelial cell cultures. In Vitro Cellular and Developmental Biology 33: 212-217, 1997.
15. Xiao BG, Bai XF, Zhang GX, and Link H: Transforming growth factor beta-1 induces apoptosis of rat microglia without relation to bcl-2 oncoprotein expression. Neuroscience Letters 226: 71-74, 1997.
16. Marushige K and Marushige Y: Induction of apoptosis by transforming growth factor beta-1 in glioma and trigeminal neurinoma cells. Anticancer Res 14: 2419-2424, 1994.
17. Buske C, Becker D, Feuring Buske M, Hannig H, Wulf G, Schaefer C, Hiddenmann W and Woermann B: TGF-beta inhibits growth and induces apoptosis in leukemic B cell precursors. Leukemia 11: 386-392, 1997.
18. Hsing AY, Kadomatsu K, Bonham MJ, and Danielpour D: Regulation of apoptosis induced by transforming growth factor-beta-1 in nontumorigenic and tumorigenic rat prostatic epithelial cell lines. Cancer Res 56: 5146-5149, 1996.
19. Yanagihara K and Tsumuraya M: Transforming growth factor beta-1 induces apoptotic cell death in human gastric carcinoma cells. Cancer Res 52: 4042-4045, 1992.
20. Yamamoto M, Maehara Y, Sakaguchi Y, Kusumoto T, Ichiyoshi Y and Sugimachi K: Transforming growth factor-beta-1 induces apoptosis in gastric cancer cells through a p53-independent pathway. Cancer 77: 1628-1633, 1996.
21. Wang CY, Eshleman JR, Willson JKV and Markovitz S: Both transforming growth factor beta and substrate release are inducers of apoptosis in a human colon adenoma cell line. Cancer Res 55: 5101-5105, 1995.
22. Lafron C, Mathieu C, Guerrin M, Pierre O, Vidal S and Valette A: Transforming growth factor beta-1-induced apoptosis in human ovarian carcinoma cells: Protection by the antioxidant N-acetylcysteine and bcl-2. Cell Growth and Differentiation 7: 1095-1104, 1996.
23. Moulton BC: Transforming growth factor beta stimulates endometrial stromal apoptosis in vitro. Endocrinology 134: 1055-1060, 1994.
24. Bauer G (Invited Review): Elimination of transformed cells by normal cells: a novel concept for the control of carcinogenesis. Histol Histopathol 11: 237-255, 1996.
25. Gentry LE, Lioubin MN, Purchio T and Marquardt H: Molecular events in the processing of recombinant type 1 pre-pro-transforming growth factor beta to the mature polypeptide. Mol Cell Biol 8: 4162-4168, 1988.
26. Gentry LE and Nash BW: The pro domain of pre-pro-transforming growth factor β1 when independently expressed is a functional binding protein for the mature growth factor. Biochemistry 29: 6851-6857, 1990.
27. Wakefield LM, Smith DM, Flanders KC and Sporn MB: Latent transforming growth factor from human platelets. A high molecular weight complex containing precursor sequences. J Biol Chem 263: 7646-7654, 1988.
28. Miyazono K, Hellman U, Wernstedt C and Heldin CH: Latent high molecular weight complex of transforming growth factor beta 1. Purification from human platelets and structural characterization. J Biol Chem 263: 6407-6415, 1988.
29. Miyazono K and Heldin CH: Latent forms of TGF-β: molecular structure and mechanisms of activation. In: Spron MB, Roberts AB (eds): Clinical applications of TGF-β. Wiley, Chichester, U.K., pp 81-92, 1991.
30. Brown PD, Wakefield LM, Levinson AD and Sporn MB: Physicochemical activation of recombinant latent transforming growth factor-beta s 1, 2 and 3. Growth Factors 3: 35-43, 1990.
31. Lyons RM, Keski-Oja J and Moses HL: Proteolytic activation of latent transforming growth factor-β from fibroblast conditioned medium. J Cell Biol 106: 1659-1665, 1988.
32. Miyazono K and Heldin CH: Role of carbohydrate structures in TGF-β latency. Nature 338: 158-160, 1989.
33. Schultz-Cherry S and Murphy-Ullrich JE: Thrombospondin causes activation of latent transforming growth factor-β secreted by endothelial cells by a novel mechanism. J Cell Biol 122: 923-932, 1993.
34. Barcellos Hoff MH and Dix TA: Redox-mediated activation of latent transforming growth factor-beta-1. Molecular Endocrinol 10: 1077-1083, 1996.
35. Coffey RJ, Goustin AS, Mangelsdorf Soderquist A, Shipley G, Wolfshohl J, Carpenter G and Moses HL: Tranforming growth factor alpha and beta expression in human colon cancer lines: implications for an autocrine model. Cancer Res 47: 4590-4594, 1987.
36. Levine AE and Lewis LR: Transforming growth factor-beta 2 is an autocrine growth inhibitory factor for the Moser human colon carcinoma cell line. Cancer Lett 68: 33-41, 1993.
37. Vossbeck H, Strahm B, Höfler P, and Bauer G: Direct transforming activity of TGF-β on rat fibroblasts. Int J Cancer 61: 92-97, 1995.
38. Dichgans C, P. Hofler and G. Bauer: Transformation of rat fibroblasts by TGF-β: restriction to a minor subpopulation, rather than a rare event. Int J Oncol 7: 1367-1371, 1995.
39. Nugent MA, Lane EA, Keski-Oja J, Moses HL and Newman MJ: Growth stimulation, altered regulation of epidermal growth factor receptors, and autocrine transformation of spontaneously transformed normal rat kidney cells by transforming growth factor β. Cancer Res 49: 3884-3890, 1989.
40. 2 are potential growth regulators for low-grade and malignant gliomas in vitro, evidence in support of an autocrine hypothesis. Int J Cancer 49: 129-139, 1991.
41. Wehrle I, Jakob A, Höfler P and Bauer G: Transformation of murine fibroblasts by UV light and TGF-β: establishment of an autocrine TGF-β loop. Int J Oncology 5: 1341-1346, 1994.
42. Bauer G and Höfler P: Epstein-Barr virus inducing factor (EIF) exhibits tumor promoting activity in vitro. J Cancer Res Clin Oncology 109(2): A 49, 1985.
43. Hamel E, Katoh F, Mueller G, Birchmaier W and Yamasaki H: Transforming growth factor β is a potent promoter in two stage Balb/c 3T3 cell transformation. Cancer Res 48: 2832-2836, 1988.
44. Fürstenberger G, Rogers M, Schnapke R, Bauer G, Hofler P and Marks F: Stimulatory role of transforming growth factors in multistage skin carcinogenesis: possible explanation for the tumor-inducing effect of wound healing in initiated NMRI mouse skin. Int J Cancer 43: 915-921, 1989.
45. Sieweke MH, Thompson NL, Sporn MB, and Bissell MJ: Mediation of wound-related Rous Sarcoma Virus tumorigencsis by TGF-β. Science 248: 1656-1660, 1990.
46. Bauer G, Götschl M and Höfler P: Tumor-promoting activity of Epstein-Barr-Virus-Inducing Factor/Transforming Growth Factor Type beta (EIF/TGF-beta 1) is due to the induction of irreversible transformation. Int J Cancer 47: 881-888, 1991.
47. Jürgensmeier J, Viesel E, Höfler P and Bauer G: TGF-β-treated normal fibroblasts eliminate transformed fibroblasts by induction of apoptosis. Cancer Res 54: 393-398, 1994.
48. Langer C, Jürgensmeier JM and Bauer G: Reactive oxygen species act both at TGF-β-dependent and -independent steps during induction of apoptosis of transformed cells by normal cells. Exp Cell Res 222: 117-124, 1996.
49. Panse J, Hipp ML and Bauer G: Fibroblasts transformed by chemical carcinogens are sensitive for intercellular induction of apoptosis: implications for the control of oncogenesis. Carcinogenesis 18: 259-264, 1997.
50. Beck E, Schafer R and Bauer G: Sensitivity of transformed fibroblasts for intercellular induction of apoptosis is determined by their transformed phenotype. Exp Cell Res 234: 47-56, 1997.
51. Hipp ML and Bauer G: Intercellular induction of apoptosis in transformed cells does not depend on p53. Oncogene 15: 791-797, 1997.
52. Geiser AG, Kim SJ, Roberts AB and Sporn MB: Characterization of the mouse transforming growth factor-beta-1 promoter and activation by the Ha-ras oncogene. Mol Cell Biol 11: 84-92, 1991.
53. Owen RD and Ostrowski MC: Transcriptional activation of a conserved sequence element by ras requires a nuclear factor distinct from c-fos or cjun. Proc Natl Acad Sci USA 87: 3866-3870, 1990.
54. Ishizaki Y, Cheng L, Mudge AW, and Raff MC: Programmed cell death by default in embryonic cells, fibroblasts, and cancer cells. Mol Biol Cell 6: 1443-1458, 1995.
55. Weil M, Jacobson MD, Coles H S R, Davies T J, Gardner R L, Raff KD and Raff MC: Constitutive expression of the machinery for programmed cell death. J Cell Biology 133: 1053-1059, 1996.
56. Wittung P and Malmstrom BG: Redox-linked conformational changes in cytochrom c oxidase. FEBS Letters 388: 47-49, 1996.
57. Schreck R, Riever P and Bauerle PA: Reactive oxygen intermediates as apparently widely used messengers in activation of the NF-kappa B transcription factor and HIV-1. EMBO J 10: 2247-2258, 1991.
58. Huang RP, Wu JX, Fan Y and Adamson ED: UV activates growth factor receptors via reactive oxygen intermediates. J Cell Biol 133: 211-220, 1996.
59. Hainaut P and Milner J: Redox modulation of p53 conformation and sequence-specific DNA binding in vitro. Cancer Res 53: 4469-4473, 1993.
60. Rainwater R, Parks D, Anderson ME, Tegtmeyer P and Mann K: Role of cysteine residues in regulation of p53 function. Mol Cell Biol 15: 3892-3903, 1995.
61. Eckert S and Bauer G: TGF-β isoforms and fibroblast growth factor exhibit analogous indirect antioncogenic activity through triggering of intercellular induction of apoptosis. Anticancer Res 18: 45-52, 1998.