-
1
-
-
0024294392
-
Guanosine triphosphatase activating protein (GAP) interacts with the p21 ras effector binding domain
-
Adari H, Lowy DR, Willumsen BM, Der CJ and McCormick F (1988) Guanosine triphosphatase activating protein (GAP) interacts with the p21 ras effector binding domain. Science 240 518-21
-
(1988)
Science
, vol.240
, pp. 518-521
-
-
Adari, H.1
Lowy, D.R.2
Willumsen, B.M.3
Der, C.J.4
McCormick, F.5
-
2
-
-
0027931640
-
Membrane targeting of the nucleotide exchange factor sos is sufficient for activating the ras signaling pathway
-
Aronheim A, Engelberg D, Li NX, Alalawi N, Schlessinger J and Karin M (1994) Membrane targeting of the nucleotide exchange factor sos is sufficient for activating the ras signaling pathway. Cell 78 949-961
-
(1994)
Cell
, vol.78
, pp. 949-961
-
-
Aronheim, A.1
Engelberg, D.2
Li, N.X.3
Alalawi, N.4
Schlessinger, J.5
Karin, M.6
-
3
-
-
0025201012
-
The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins
-
Ballester R, Marchuk D, Boguski M et al (1990) The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins. Cell 63 851-859
-
(1990)
Cell
, vol.63
, pp. 851-859
-
-
Ballester, R.1
Marchuk, D.2
Boguski, M.3
-
5
-
-
0025226084
-
Caenorhabditis elegans ras gene let-60 acts as a switch in the pathway of vulval induction
-
Beitel GJ, Clark SG and Horvitz HR (1990) Caenorhabditis elegans ras gene let-60 acts as a switch in the pathway of vulval induction. Nature 348 503-509
-
(1990)
Nature
, vol.348
, pp. 503-509
-
-
Beitel, G.J.1
Clark, S.G.2
Horvitz, H.R.3
-
6
-
-
0026608238
-
The son of sevenless gene product: A putative activator of ras
-
Bonfini L, Karlovich CA, Dasgupta C and Banerjee U (1992) The son of sevenless gene product: a putative activator of ras. Science 255 603-606
-
(1992)
Science
, vol.255
, pp. 603-606
-
-
Bonfini, L.1
Karlovich, C.A.2
Dasgupta, C.3
Banerjee, U.4
-
7
-
-
0024376173
-
ras oncogenes in human cancer: A review
-
Bos JL (1989) ras oncogenes in human cancer: a review. Cancer Research 49 4682-4689
-
(1989)
Cancer Research
, vol.49
, pp. 4682-4689
-
-
Bos, J.L.1
-
9
-
-
0024602535
-
The C-terminal part of a gene partially homologous to CDC25 gene suppresses the cdc25-5 mutation in S. cerevisiae
-
Boy-Marcotte E, Damak F, Camonis J, Garreau H and Jacquet M (1989) The C-terminal part of a gene partially homologous to CDC25 gene suppresses the cdc25-5 mutation in S. cerevisiae. Gene 77 21-30
-
(1989)
Gene
, vol.77
, pp. 21-30
-
-
Boy-Marcotte, E.1
Damak, F.2
Camonis, J.3
Garreau, H.4
Jacquet, M.5
-
10
-
-
0023652371
-
The S. cerevisiae CDC25 gene product regulates the RAS/adenylate cyclase pathway
-
Broek D, Toda T, Michaeli T, Levin L et al (1987) The S. cerevisiae CDC25 gene product regulates the RAS/adenylate cyclase pathway. Cell 48 789-799
-
(1987)
Cell
, vol.48
, pp. 789-799
-
-
Broek, D.1
Toda, T.2
Michaeli, T.3
Levin, L.4
-
11
-
-
0025152970
-
Sequence homology shared by neurofibromatosis type-1 gene and IRA-1 and IRA-2 negative regulators of the RAS and cyclic AMP pathway
-
Buchberg AM, Cleveland LS, Jenkins NA and Copeland NG (1990) Sequence homology shared by neurofibromatosis type-1 gene and IRA-1 and IRA-2 negative regulators of the RAS and cyclic AMP pathway. Nature 347 291-294
-
(1990)
Nature
, vol.347
, pp. 291-294
-
-
Buchberg, A.M.1
Cleveland, L.S.2
Jenkins, N.A.3
Copeland, N.G.4
-
12
-
-
0027153103
-
EGF regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein and Sos nucleotide exchange factor
-
Buday L and Downward J (1993a) EGF regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein and Sos nucleotide exchange factor. Cell 73 611-620
-
(1993)
Cell
, vol.73
, pp. 611-620
-
-
Buday, L.1
Downward, J.2
-
13
-
-
0027465064
-
Epidermal growth factor regulates the exchange rate of guanine nucleotides on p21ras in fibroblasts
-
Buday L and Downward J (1993b) Epidermal growth factor regulates the exchange rate of guanine nucleotides on p21ras in fibroblasts. Molecular and Cellular Biology 13 1903-1910
-
(1993)
Molecular and Cellular Biology
, vol.13
, pp. 1903-1910
-
-
Buday, L.1
Downward, J.2
-
14
-
-
0028857006
-
Downregulation of the Ras activation pathway by MAP kinase phosphorylation of Sos
-
Buday L, Warne PH and Downward J (1995) Downregulation of the Ras activation pathway by MAP kinase phosphorylation of Sos. Oncogens 11 1327-1331
-
(1995)
Oncogens
, vol.11
, pp. 1327-1331
-
-
Buday, L.1
Warne, P.H.2
Downward, J.3
-
15
-
-
0027501802
-
cAMP antagonizes p21ras directed activation of extracellular signal-regulated kinase 2 and phosphorylation of mSos nucleotide exchange factor
-
Burgering BMT, Pronk GJ, van Weeren PC, Chardin P and Bos JL (1993) cAMP antagonizes p21ras directed activation of extracellular signal-regulated kinase 2 and phosphorylation of mSos nucleotide exchange factor. EMBO Journal 12 4211-4220
-
(1993)
EMBO Journal
, vol.12
, pp. 4211-4220
-
-
Burgering, B.M.T.1
Pronk, G.J.2
Van Weeren, P.C.3
Chardin, P.4
Bos, J.L.5
-
16
-
-
0024280502
-
The cytoplasmic protein GAP is implicated as the target for regulation by the ras gene product
-
Cales C, Hancock JF, Marshall CJ and Hall A (1988) The cytoplasmic protein GAP is implicated as the target for regulation by the ras gene product. Nature 332 548-551
-
(1988)
Nature
, vol.332
, pp. 548-551
-
-
Cales, C.1
Hancock, J.F.2
Marshall, C.J.3
Hall, A.4
-
17
-
-
0027304731
-
Human Sos1 a guanine nucleotide exchange factor for Ras that binds to Grb2
-
Chardin P, Camonis JH, Gale NW et al (1993) Human Sos1 a guanine nucleotide exchange factor for Ras that binds to Grb2. Science 260 1338-1343
-
(1993)
Science
, vol.260
, pp. 1338-1343
-
-
Chardin, P.1
Camonis, J.H.2
Gale, N.W.3
-
18
-
-
0027365376
-
A murine CDC25/ras-GRF-related protein implicated in Ras regulation
-
Chen L, Zhang LJ, Greer P, Tung PS and Moran MF (1993) A murine CDC25/ras-GRF-related protein implicated in Ras regulation. Developmental Genetics 14 339-346
-
(1993)
Developmental Genetics
, vol.14
, pp. 339-346
-
-
Chen, L.1
Zhang, L.J.2
Greer, P.3
Tung, P.S.4
Moran, M.F.5
-
20
-
-
0025365849
-
Enhancement of the GDP-GTP exchange of RAS proteins by the carboxyl-terminal domain of SCD25
-
Crechet J-B, Poullet P, Mistou M-Y et al (1990) Enhancement of the GDP-GTP exchange of RAS proteins by the carboxyl-terminal domain of SCD25. Science 248 866-868
-
(1990)
Science
, vol.248
, pp. 866-868
-
-
Crechet, J.-B.1
Poullet, P.2
Mistou, M.-Y.3
-
21
-
-
0029112873
-
Identification of a specific Ins(1,3,4,5)P4-binding protein as a member of the GAP1 family
-
Cullen PJ, Hsuan JJ, Truong O et al (1995) Identification of a specific Ins(1,3,4,5)P4-binding protein as a member of the GAP1 family. Nature 376 527-530
-
(1995)
Nature
, vol.376
, pp. 527-530
-
-
Cullen, P.J.1
Hsuan, J.J.2
Truong, O.3
-
22
-
-
0023117310
-
Insulin induction of Xenopus laevis oocyte maturation is inhibited by monoclonal antibody against p21 ras protein
-
Deshpande AK and Kung H-F (1987) Insulin induction of Xenopus laevis oocyte maturation is inhibited by monoclonal antibody against p21 ras protein. Molecular and Cellular Biology 7 1285-1288
-
(1987)
Molecular and Cellular Biology
, vol.7
, pp. 1285-1288
-
-
Deshpande, A.K.1
Kung, H.-F.2
-
24
-
-
0027339729
-
Identification of the SH3 domain of GAP as an essential sequence for Ras-GAP mediated signaling
-
Duchesne M, Schweighoffer F, Parker F et al (1993) Identification of the SH3 domain of GAP as an essential sequence for Ras-GAP mediated signaling. Science 259 525-528
-
(1993)
Science
, vol.259
, pp. 525-528
-
-
Duchesne, M.1
Schweighoffer, F.2
Parker, F.3
-
25
-
-
0027910431
-
Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation
-
Egan SE, Giddings BW, Brooks MW, Buday L, Sizeland AM and Weinberg RA (1993) Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation. Nature 363 45-51
-
(1993)
Nature
, vol.363
, pp. 45-51
-
-
Egan, S.E.1
Giddings, B.W.2
Brooks, M.W.3
Buday, L.4
Sizeland, A.M.5
Weinberg, R.A.6
-
26
-
-
0025177324
-
Phosphorylation of GAP-associated proteins by transforming and mitogenic tyrosine kinases
-
Ellis C, Moran M, McCormick F and Pawson T (1990) Phosphorylation of GAP-associated proteins by transforming and mitogenic tyrosine kinases. Nature 343 377-381
-
(1990)
Nature
, vol.343
, pp. 377-381
-
-
Ellis, C.1
Moran, M.2
McCormick, F.3
Pawson, T.4
-
27
-
-
0029098537
-
Calcium activation of Ras mediated by neuronal exchange factor Ras-GRF
-
Farnsworth CL, Freshney NW, Rosen LB, Ghosh A, Greenberg ME and Feig LA (1995) Calcium activation of Ras mediated by neuronal exchange factor Ras-GRF. Nature 376 524-527
-
(1995)
Nature
, vol.376
, pp. 524-527
-
-
Farnsworth, C.L.1
Freshney, N.W.2
Rosen, L.B.3
Ghosh, A.4
Greenberg, M.E.5
Feig, L.A.6
-
28
-
-
0029991920
-
Blocked Ras activation in anergic CD4+ T cells
-
Fields PE, Gajewski TF and Fitch FW (1996) Blocked Ras activation in anergic CD4+ T cells. Science 271 1276-1278
-
(1996)
Science
, vol.271
, pp. 1276-1278
-
-
Fields, P.E.1
Gajewski, T.F.2
Fitch, F.W.3
-
29
-
-
0026575220
-
Signalling by the sevenless protein tyrosine kinase is mimicked by rasl action
-
Fortini ME, Simon MA and Rubin GM (1992) Signalling by the sevenless protein tyrosine kinase is mimicked by rasl action. Nature 355 559-561
-
(1992)
Nature
, vol.355
, pp. 559-561
-
-
Fortini, M.E.1
Simon, M.A.2
Rubin, G.M.3
-
30
-
-
0019958484
-
Monoclonal antibodies to the p21 products of the transforming gene of Harvey murine sarcoma virus and of the cellular ras gene family
-
Furth ME, Davis LJ, Fleurdelys B and Scolnick EM (1982) Monoclonal antibodies to the p21 products of the transforming gene of Harvey murine sarcoma virus and of the cellular ras gene family. Journal of Virology 43 294-304
-
(1982)
Journal of Virology
, vol.43
, pp. 294-304
-
-
Furth, M.E.1
Davis, L.J.2
Fleurdelys, B.3
Scolnick, E.M.4
-
31
-
-
0023062991
-
G proteins: Transducers of receptor-generated signals
-
Gilman AG (1987) G proteins: transducers of receptor-generated signals. Annual Reviews of Biochemistry 56 615-649
-
(1987)
Annual Reviews of Biochemistry
, vol.56
, pp. 615-649
-
-
Gilman, A.G.1
-
32
-
-
0023107398
-
Sevenless, a cell-specific homeotic gene of Drosophila, encodes a putative transmembrane receptor with a tyrosine kinase domain
-
Hafen E, Basler K, Edstroem J-E and Rubin GM (1987) Sevenless, a cell-specific homeotic gene of Drosophila, encodes a putative transmembrane receptor with a tyrosine kinase domain. Science 236 55-63
-
(1987)
Science
, vol.236
, pp. 55-63
-
-
Hafen, E.1
Basler, K.2
Edstroem, J.-E.3
Rubin, G.M.4
-
33
-
-
0022602017
-
Inhibition of growth factor-induced differentiation of PC12 cells by microinjection of antibody to ras p21
-
Hagag N, Halegoua S and Viola M (1986) Inhibition of growth factor-induced differentiation of PC12 cells by microinjection of antibody to ras p21. Nature 319 680-682
-
(1986)
Nature
, vol.319
, pp. 680-682
-
-
Hagag, N.1
Halegoua, S.2
Viola, M.3
-
34
-
-
0022930104
-
The effect of Mg2+ on the guanine nucleotide exchange rate of p21N-ras
-
Hall A and Self AJ (1986) The effect of Mg2+ on the guanine nucleotide exchange rate of p21N-ras. Journal of Biological Chemistry 261 10963-10965
-
(1986)
Journal of Biological Chemistry
, vol.261
, pp. 10963-10965
-
-
Hall, A.1
Self, A.J.2
-
35
-
-
0025633434
-
Let-60, a gene that specifies cell fates during C. elegans vulval induction, encodes a ras protein
-
Han M and Sternberg PW (1990) let-60, a gene that specifies cell fates during C. elegans vulval induction, encodes a ras protein. Cell 63 921-931
-
(1990)
Cell
, vol.63
, pp. 921-931
-
-
Han, M.1
Sternberg, P.W.2
-
36
-
-
0024406286
-
All ras proteins are polyisoprenylated but only some are palmitoylated
-
Hancock JF, Magee AI, Childs JE and Marshall CJ (1989) All ras proteins are polyisoprenylated but only some are palmitoylated. Cell 57 1167-1177
-
(1989)
Cell
, vol.57
, pp. 1167-1177
-
-
Hancock, J.F.1
Magee, A.I.2
Childs, J.E.3
Marshall, C.J.4
-
37
-
-
0025013547
-
A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane
-
Hancock JF, Paterson H and Marshall CJ (1990) A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane. Cell 63 133-139
-
(1990)
Cell
, vol.63
, pp. 133-139
-
-
Hancock, J.F.1
Paterson, H.2
Marshall, C.J.3
-
38
-
-
0028788570
-
Vascular system defects and neuronal apoptosis in mice lacking ras GTPase-activating protein
-
Henkemeyer M, Rossi DJ, Holmyard D et al (1995) Vascular system defects and neuronal apoptosis in mice lacking ras GTPase-activating protein. Nature 377 695-701
-
(1995)
Nature
, vol.377
, pp. 695-701
-
-
Henkemeyer, M.1
Rossi, D.J.2
Holmyard, D.3
-
39
-
-
0030030357
-
Insulin stimulation of a mek-dependent but erk-independent sos protein-kinase
-
Holt KH, Kasson BG and Pessin JE (1996) Insulin stimulation of a mek-dependent but erk-independent sos protein-kinase. Molecular and Cellular Biology 16 577-583
-
(1996)
Molecular and Cellular Biology
, vol.16
, pp. 577-583
-
-
Holt, K.H.1
Kasson, B.G.2
Pessin, J.E.3
-
40
-
-
0028307836
-
Tumour predisposition in mice heterozygous for a targeted mutation in NF1
-
Jacks T, Shih TS, Schmitt EM, Bronson RT, Bernards A and Weinberg RA (1994) Tumour predisposition in mice heterozygous for a targeted mutation in NF1. Nature Genetics 7 353-361
-
(1994)
Nature Genetics
, vol.7
, pp. 353-361
-
-
Jacks, T.1
Shih, T.S.2
Schmitt, E.M.3
Bronson, R.T.4
Bernards, A.5
Weinberg, R.A.6
-
41
-
-
0027986765
-
Ral-gds family members interact with the effector loop of ras p21
-
Kikuchi A, Demo SD, Ye ZH, Chen YW and Williams LT (1994) Ral-gds family members interact with the effector loop of ras p21. Molecular and Cellular Biology 14 7483-7491
-
(1994)
Molecular and Cellular Biology
, vol.14
, pp. 7483-7491
-
-
Kikuchi, A.1
Demo, S.D.2
Ye, Z.H.3
Chen, Y.W.4
Williams, L.T.5
-
42
-
-
0028874343
-
Divergent mechanisms for homologous desensitization of p21ras by insulin and growth factors
-
Klarlund JK, Cherniack AD and Czech MP (1995) Divergent mechanisms for homologous desensitization of p21ras by insulin and growth factors. Journal of Biological Chemistry 270 23421-23428
-
(1995)
Journal of Biological Chemistry
, vol.270
, pp. 23421-23428
-
-
Klarlund, J.K.1
Cherniack, A.D.2
Czech, M.P.3
-
43
-
-
0028606468
-
Four proline-rich sequences of the guanine-nucleotide exchange factor C3G bind with unique specificity to the first Src homology 3 domain of Crk
-
Knudsen BS, Feller SM and Hanafusa H (1994) Four proline-rich sequences of the guanine-nucleotide exchange factor C3G bind with unique specificity to the first Src homology 3 domain of Crk. Journal of Biological Chemistry 269 32781-32787
-
(1994)
Journal of Biological Chemistry
, vol.269
, pp. 32781-32787
-
-
Knudsen, B.S.1
Feller, S.M.2
Hanafusa, H.3
-
44
-
-
0023182603
-
Ras p21 as a potential mediator of insulin action in Xenopus oocytes
-
Kom LJ, Siebel CW, McCormick F and Roth RA (1987) Ras p21 as a potential mediator of insulin action in Xenopus oocytes. Science 236 840-843
-
(1987)
Science
, vol.236
, pp. 840-843
-
-
Kom, L.J.1
Siebel, C.W.2
McCormick, F.3
Roth, R.A.4
-
45
-
-
0027312272
-
Guanine nucleotide releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling
-
Li N, Batzer A, Daly R et al (1993) Guanine nucleotide releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling. Nature 363 85-88
-
(1993)
Nature
, vol.363
, pp. 85-88
-
-
Li, N.1
Batzer, A.2
Daly, R.3
-
47
-
-
0026523616
-
Cloning by functional complementation of a mouse cDNA encoding a homologue of CDC25, a Saccharomyces cerevisiae ras activator
-
Martegani E, Vanoni M, Zippel R et al (1992) Cloning by functional complementation of a mouse cDNA encoding a homologue of CDC25, a Saccharomyces cerevisiae ras activator. EMBO Journal 6 2151-2157
-
(1992)
EMBO Journal
, vol.6
, pp. 2151-2157
-
-
Martegani, E.1
Vanoni, M.2
Zippel, R.3
-
48
-
-
0025251137
-
The GAP-related domain of the neurofibromatosis type 1 gene product interacts with ras p21
-
Martin GA, Viskochil D, Bollag G et al (1990) The GAP-related domain of the neurofibromatosis type 1 gene product interacts with ras p21. Cell 63 843-849
-
(1990)
Cell
, vol.63
, pp. 843-849
-
-
Martin, G.A.1
Viskochil, D.2
Bollag, G.3
-
49
-
-
0026778344
-
GTPase activating protein SH2-SH3 domains induce gene expression in a ras-dependent fashion
-
Medema RH, de Laat WL, Martin GA, McCormick F and Bos JL (1992) GTPase activating protein SH2-SH3 domains induce gene expression in a ras-dependent fashion. Molecular Cellular Biology 12 3425-3430
-
(1992)
Molecular Cellular Biology
, vol.12
, pp. 3425-3430
-
-
Medema, R.H.1
De Laat, W.L.2
Martin, G.A.3
McCormick, F.4
Bos, J.L.5
-
50
-
-
0025117674
-
Molecular switch for signal transduction: Structural differences between active and inactive forms of protooncogenic ras proteins
-
Milburn MV, Tong L, deVos AM et al (1990) Molecular switch for signal transduction: structural differences between active and inactive forms of protooncogenic ras proteins. Science 247 939-945
-
(1990)
Science
, vol.247
, pp. 939-945
-
-
Milburn, M.V.1
Tong, L.2
DeVos, A.M.3
-
52
-
-
0025967106
-
Protein tyrosine kinases regulate the phosphorylation, protein interactions, subcellular distribution and activity of p21ras GTPase activating protein
-
Moran MF, Polakis P, McCormick F, Pawson T and Ellis C (1991) Protein tyrosine kinases regulate the phosphorylation, protein interactions, subcellular distribution and activity of p21ras GTPase activating protein. Molecular and Cellular Biology 11 1804-1812
-
(1991)
Molecular and Cellular Biology
, vol.11
, pp. 1804-1812
-
-
Moran, M.F.1
Polakis, P.2
McCormick, F.3
Pawson, T.4
Ellis, C.5
-
53
-
-
0021970413
-
Requirement for ras proto-oncogene function during serum-stimulated growth of NIH 3T3 cells
-
Mulcahy LS, Smith MR and Stacey DW (1985) Requirement for ras proto-oncogene function during serum-stimulated growth of NIH 3T3 cells. Nature 313 241-243
-
(1985)
Nature
, vol.313
, pp. 241-243
-
-
Mulcahy, L.S.1
Smith, M.R.2
Stacey, D.W.3
-
54
-
-
0027468233
-
A Drosophila SH2-SH3 adaptor protein implicated in coupling the sevenless tyrosine kinase to an activator of Ras guanine nucleotide exchange, Sos
-
Olivier JP, Raabe T, Henkemeyer M et al (1993) A Drosophila SH2-SH3 adaptor protein implicated in coupling the sevenless tyrosine kinase to an activator of Ras guanine nucleotide exchange, Sos. Cell 73 179-191
-
(1993)
Cell
, vol.73
, pp. 179-191
-
-
Olivier, J.P.1
Raabe, T.2
Henkemeyer, M.3
-
56
-
-
0028074316
-
Phosphatidylinositol-3-OH kinase as a direct target of Ras
-
Rodriguez-Viciana P, Warne PH et al (1994) Phosphatidylinositol-3-OH kinase as a direct target of Ras. Nature 370 527-532
-
(1994)
Nature
, vol.370
, pp. 527-532
-
-
Rodriguez-Viciana, P.1
Warne, P.H.2
-
57
-
-
0027294981
-
The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1
-
Rozakis Adcock M, Femley R, Wade J, Pawson T and Bowtell D (1993) The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1. Nature 363 83-85
-
(1993)
Nature
, vol.363
, pp. 83-85
-
-
Rozakis Adcock, M.1
Femley, R.2
Wade, J.3
Pawson, T.4
Bowtell, D.5
-
58
-
-
0028789820
-
MAP kinase phosphorylation of mSos1 promotes dissociation of mSos1-Shc and mSos1-EGF receptor complexes
-
Rozakis-Adcock M, van der Geer P, Mbamalu G and Pawson T (1995) MAP kinase phosphorylation of mSos1 promotes dissociation of mSos1-Shc and mSos1-EGF receptor complexes. Oncogene 11 1417-1426
-
(1995)
Oncogene
, vol.11
, pp. 1417-1426
-
-
Rozakis-Adcock, M.1
Van Der Geer, P.2
Mbamalu, G.3
Pawson, T.4
-
59
-
-
0024973845
-
Development of the Drosophila retina: Inductive events studied at single cell resolution
-
Rubin GM (1989) Development of the Drosophila retina: inductive events studied at single cell resolution. Cell 57 519-520
-
(1989)
Cell
, vol.57
, pp. 519-520
-
-
Rubin, G.M.1
-
60
-
-
0025275582
-
Time-resolved X-ray crystallographic study of the conformational change in Ha-Ras p21 protein on GTP hydrolysis
-
Schlichting I, Almo SC, Rapp G et al (1990) Time-resolved X-ray crystallographic study of the conformational change in Ha-Ras p21 protein on GTP hydrolysis. Nature 345 309-315
-
(1990)
Nature
, vol.345
, pp. 309-315
-
-
Schlichting, I.1
Almo, S.C.2
Rapp, G.3
-
61
-
-
0026587137
-
Implication of GAP in Ras-dependent transactivation of a polyoma enhancer sequence
-
Schweighoffer F, Barlat I, Chevalier-Multon M-C and Tocque B (1992) Implication of GAP in Ras-dependent transactivation of a polyoma enhancer sequence. Science 256 825-827
-
(1992)
Science
, vol.256
, pp. 825-827
-
-
Schweighoffer, F.1
Barlat, I.2
Chevalier-Multon, M.-C.3
Tocque, B.4
-
62
-
-
0026740716
-
Molecular cloning of cDNAs encoding the GAP-associated protein p190: Implications for a signalling pathway from ras to the nucleus
-
Settleman J, Narasimhan V, Foster LC and Weinberg RA (1992) Molecular cloning of cDNAs encoding the GAP-associated protein p190: implications for a signalling pathway from ras to the nucleus. Cell 69 539-549
-
(1992)
Cell
, vol.69
, pp. 539-549
-
-
Settleman, J.1
Narasimhan, V.2
Foster, L.C.3
Weinberg, R.A.4
-
63
-
-
0026659515
-
Molecular cloning of cDNAs encoding a guanine-nucleotide releasing factor for ras-p21
-
Shou C, Farnsworth CL, Neel BG and Feig LA (1992) Molecular cloning of cDNAs encoding a guanine-nucleotide releasing factor for ras-p21. Nature 358 351-354
-
(1992)
Nature
, vol.358
, pp. 351-354
-
-
Shou, C.1
Farnsworth, C.L.2
Neel, B.G.3
Feig, L.A.4
-
64
-
-
0025997867
-
Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase
-
Simon MA, Bowtell DDL, Dodson GS, Laverty TR and Rubin GM (1991) Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase. Cell 67 701-716
-
(1991)
Cell
, vol.67
, pp. 701-716
-
-
Simon, M.A.1
Bowtell, D.D.L.2
Dodson, G.S.3
Laverty, T.R.4
Rubin, G.M.5
-
65
-
-
0027404990
-
An SH3-SH2-SH3 protein is required for p21Ras1 activation and binds to sevenless and Sos proteins in vitro
-
Simon MA, Dodson GS and Rubin GM (1993) An SH3-SH2-SH3 protein is required for p21Ras1 activation and binds to sevenless and Sos proteins in vitro. Cell 73 169-177
-
(1993)
Cell
, vol.73
, pp. 169-177
-
-
Simon, M.A.1
Dodson, G.S.2
Rubin, G.M.3
-
66
-
-
0022472990
-
Requirement for c-ras proteins during viral oncogene transformation
-
Smith MR, DeGudicibus SJ and Stacey DW (1986) Requirement for c-ras proteins during viral oncogene transformation. Nature 320 540-543
-
(1986)
Nature
, vol.320
, pp. 540-543
-
-
Smith, M.R.1
DeGudicibus, S.J.2
Stacey, D.W.3
-
67
-
-
0025021774
-
Identifying tumor suppressor genes in human colorectal cancer
-
Stanbridge EJ (1990) Identifying tumor suppressor genes in human colorectal cancer. Science 247 12-13
-
(1990)
Science
, vol.247
, pp. 12-13
-
-
Stanbridge, E.J.1
-
68
-
-
0028264812
-
C3g, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the src homology-3 domains of crk and grb2 ash proteins
-
Tanaka S, Morishita T, Hashimoto Y et al (1994) C3g, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the src homology-3 domains of crk and grb2 ash proteins. Proceedings of the National Academy of Sciences of the USA 91 3443-3447
-
(1994)
Proceedings of the National Academy of Sciences of the USA
, vol.91
, pp. 3443-3447
-
-
Tanaka, S.1
Morishita, T.2
Hashimoto, Y.3
-
70
-
-
0023619575
-
A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect oncogenic mutants
-
Trahey M and McCormick F (1987) A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect oncogenic mutants. Science 238 542-545
-
(1987)
Science
, vol.238
, pp. 542-545
-
-
Trahey, M.1
McCormick, F.2
-
71
-
-
0024212303
-
Molecular cloning of two types of GAP complementary DNA from human placenta
-
Trahey M, Wong G, Halenbeck R et al (1988) Molecular cloning of two types of GAP complementary DNA from human placenta. Science 242 1697-700
-
(1988)
Science
, vol.242
, pp. 1697-1700
-
-
Trahey, M.1
Wong, G.2
Halenbeck, R.3
-
72
-
-
0023681723
-
Cloning of bovine GAP and its interaction with oncogenic ras p21
-
Vogel US, Dixon RA, Schaber MD, Diehl RE, Marshall MS, Scolnick EM, Sigal IS and Gibbs JB (1988) Cloning of bovine GAP and its interaction with oncogenic ras p21. Nature 335 90-93
-
(1988)
Nature
, vol.335
, pp. 90-93
-
-
Vogel, U.S.1
Dixon, R.A.2
Schaber, M.D.3
Diehl, R.E.4
Marshall, M.S.5
Scolnick, E.M.6
Sigal, I.S.7
Gibbs, J.B.8
-
73
-
-
0025297599
-
Type 1 neurofibromatosis gene: Identification of a large transcript disrupted in three NF1 patients
-
Wallace MR, Marchuk DA, Andersen LB et al (1990) Type 1 neurofibromatosis gene: identification of a large transcript disrupted in three NF1 patients. Science 249 181-186
-
(1990)
Science
, vol.249
, pp. 181-186
-
-
Wallace, M.R.1
Marchuk, D.A.2
Andersen, L.B.3
-
74
-
-
0029130317
-
Desensitization of Ras activation by a feedback disassociation of the SOS-Grb2 complex
-
Waters SB, Holt KH, Ross SE et al (1995a) Desensitization of Ras activation by a feedback disassociation of the SOS-Grb2 complex. Journal of Biological Chemistry 270 20883-20886
-
(1995)
Journal of Biological Chemistry
, vol.270
, pp. 20883-20886
-
-
Waters, S.B.1
Holt, K.H.2
Ross, S.E.3
-
76
-
-
0028033549
-
Identification of a human rasGAP-related protein containing calmodulin-binding motifs
-
Weissbach L, Settleman J, Kalady MF et al (1994) Identification of a human rasGAP-related protein containing calmodulin-binding motifs. Journal of Biological Chemistry 269 20517-20521
-
(1994)
Journal of Biological Chemistry
, vol.269
, pp. 20517-20521
-
-
Weissbach, L.1
Settleman, J.2
Kalady, M.F.3
-
78
-
-
0025091465
-
The neurofibromatosis type 1 gene encodes a protein related to GAP
-
Xu G, O'Connell P, Viskochil D et al (1990) The neurofibromatosis type 1 gene encodes a protein related to GAP. Cell 62 599-608
-
(1990)
Cell
, vol.62
, pp. 599-608
-
-
Xu, G.1
O'Connell, P.2
Viskochil, D.3
-
79
-
-
0025324939
-
Ras p21 and GAP inhibit coupling of muscarinic receptors to atrial K+ channels
-
Yatani A, Okabe K, Polakis P, Halenbeck R, McCormick F and Brown AM (1990) Ras p21 and GAP inhibit coupling of muscarinic receptors to atrial K+ channels. Cell 61 769-776
-
(1990)
Cell
, vol.61
, pp. 769-776
-
-
Yatani, A.1
Okabe, K.2
Polakis, P.3
Halenbeck, R.4
McCormick, F.5
Brown, A.M.6
-
80
-
-
0023864810
-
Cellular ras activity and phospholipid metabolism
-
Yu CL, Tsai MH and Stacey DW (1988) Cellular ras activity and phospholipid metabolism. Cell 52 63-71
-
(1988)
Cell
, vol.52
, pp. 63-71
-
-
Yu, C.L.1
Tsai, M.H.2
Stacey, D.W.3
|