Expression of Bcl-X(L) restores cell survival, but not proliferation and effector differentiation, in CD28-deficient T lymphocytes

Journal of Experimental Medicine

Volumn 191, Issue 12, 2000, Pages 2031-2037

  Dahl, A Maria ^a   Klein, Christoph ^b   Andres, Pietro G ^a,c   London, Cheryl A ^a   Lodge, Michael P ^a,d   Mulligan, Richard C ^b   Abbas, Abul K ^a,c,e  

^a HARVARD MEDICAL SCHOOL   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Bone marrow reconstitution; CD4+ T lymphocyte; Costimulation; Retrovirus mediated gene transfer; Th2 differentiation

Indexed keywords

CD28 ANTIGEN; PROTEIN BCL X;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL SURVIVAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE EXPRESSION; GENE TRANSFER; HEMATOPOIETIC STEM CELL; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RETROVIRUS; T LYMPHOCYTE; TRANSGENIC MOUSE;

ANIMALS; ANTIGENS, CD28; BCL-X PROTEIN; BONE MARROW TRANSPLANTATION; CELL DIFFERENTIATION; CELL DIVISION; CELL SURVIVAL; GENE TRANSFER TECHNIQUES; GENETIC COMPLEMENTATION TEST; LYMPHOCYTE ACTIVATION; MICE; MICE, TRANSGENIC; PROTO-ONCOGENE PROTEINS C-BCL-2; RADIATION CHIMERA; RETROVIRIDAE; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TH2 CELLS;

EID: 0034686446     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.191.12.2031     Document Type: Article

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