Suppression by a sesquiterpene lactone from Carpesium divaricatum of inducible nitric oxide synthase by inhibiting nuclear factor-κB activation

Biochemical Pharmacology

Volumn 61, Issue 7, 2001, Pages 903-910

  Ju Kim, Eun ^a   Jin, Hye Kyoung ^a   Kim, Yong Kee ^a   Lee, Hoi Young ^b   Lee, Seok Yong ^a   Lee, Kang Ro ^a   Zee, Ok Pyo ^a   Han, Jeung Whan ^a   Lee, Hyang Woo ^a  

^a Sungkyunkwan University   (South Korea)

^b Konyang University   (South Korea)

Author keywords

I B; Inducible nitric oxide synthase; NF B; Sesquiterpene lactone

Indexed keywords

2 BETA,5 EPOXY 5,10 DIHYDROXY 6 ALPHA ANGELOYLOXY 9 BETA ISOBUTYLOXY GERMACRAN 8 ALPHA,12 OLIDE; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; SESQUITERPENE LACTONE; SYNAPTOTAGMIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIOSYNTHESIS; CELL LEVEL; CELL NUCLEUS; CELL VIABILITY; CONTROLLED STUDY; DNA BINDING; DRUG EFFECT; ENZYME ACTIVITY; ENZYME INDUCTION; GENE EXPRESSION; IC 50; MITOCHONDRIAL RESPIRATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION;

ANIMALS; BIOLOGICAL TRANSPORT; CATALYSIS; CELL NUCLEUS; CELL SURVIVAL; CELLS, CULTURED; DNA-BINDING PROTEINS; ENZYME REPRESSION; I-KAPPA B PROTEINS; INTERFERON TYPE II; LIGASES; LIPOPOLYSACCHARIDES; MICE; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; NITRITES; PHYTOTHERAPY; PLANTS, MEDICINAL; RNA, MESSENGER; SESQUITERPENES;

EID: 0035313242     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(01)00538-X     Document Type: Article

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